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Gastric cancer (GC) represents a serious health problem on a global scale. Despite some recent advances in the field, the prognosis in GC remains poor. A better understanding of molecular biology, which would lead to improved treatment options, is needed. Many potential biomarkers of prognostic significance ...

Gastric cancer (GC) represents a serious health problem on a global scale. Despite some recent advances in the field, the prognosis in GC remains poor. A better understanding of molecular biology, which would lead to improved treatment options, is needed. Many potential biomarkers of prognostic significance have been identified. However, inhibition of only HER2 protein has led to a modest survival benefit. A deeper understanding of the pathogenesis and biological features of gastric cancer, including the identification and characterization of diagnostic, prognostic, predictive, and therapeutic biomarkers, hopefully will provide improved clinical outcomes.

This Research Topic aims to provide a comprehensive overview on recent progress in emerging molecular biomarkers for gastric cancer. We welcome the submission of Review and Original Research articles covering, but not limited to, the following topics:

1)Novel diagnostic molecules to improve the early detection rate for gastric cancer
2)Novel prognostic molecules to stratify gastric cancer patients into different risk
3)Novel therapeutic biomarker which could serve as target for treating gastric cancer
4)Novel biomarker to predict chemotherapy response of gastric cancer patients

Keywords: gastric cancer, diagnosis, prognosis, novel therapeutic targets, molecular biomarkers


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