About this Research Topic
To commemorate the 100th anniversary of the discovery and successful purification of insulin at the University of Toronto by Banting, Best, Collip and McLeod in 1921 (earning the Nobel Prize to Banting and McLeod in 1923), Frontiers in Endocrinology is organizing a special collection related to insulin and insulin-like peptides, with Jeff M.P. Holly and Pierre De Meyts as supervisory editors. Over the last 100 years, the study of insulin has pioneered many of the important milestones of modern endocrinology. Insulin was not only the first hormone to be isolated but also the first to be measured by radioimmunoassay. It was also the first human protein to be sequenced, structurally characterized and then synthesized and manufactured for clinical use, affecting millions of lives. We aim to bring together a collection of articles to celebrate the anniversary and the continued breadth of studies of this remarkable hormone.
Each of the 17 Specialty Sections of Frontiers in Endocrinology is calling for papers (reviews and mini-reviews) within the scope of each Specialty, and manuscripts will be edited by the Specialty Chief Editor. In the end all published articles will be collected into a unique commemorative eBook. The Chief Editors are inviting potential contributors, but spontaneous submissions are also welcome and should be submitted to the section that best fits the scope of the submission.
Multiple aspects of insulin and insulin-like peptides will be considered, including but not limited to, structure, evolution, mechanism of action and signaling, role in physiology, metabolism, lifespan, CNS function, pathophysiology of metabolic diseases, cancer and neurodegenerative diseases, and therapeutic applications. Articles with an original historical insight are also welcome.
Keywords: Insulin, Insulin-like peptide
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.