Genetics of Complex Traits & Diseases from Under-Represented Populations

52.5K

views

69

authors

11

articles

Genetics of Complex Traits & Diseases from Under-Represented Populations

52.5K

views

69

authors

11

articles

Editorial

17 January 2022

Editorial: Genetics of Complex Traits and Diseases From Under-Represented Populations

Segun Fatumo

,

Tinashe Chikowore

and

Karoline Kuchenbaecker

2,058 views

1 citations

Editors

3

Queen Mary University of London

Tinashe Chikowore

University of the Witwatersrand

Karoline Kuchenbaecker

University College London

Impact

About

Our genes play a role in the occurrence of diseases and the characteristics of complex traits. An understanding of the interplay of these genes and environmental factors is essential for the development of effective therapeutic approaches for the management of diseases. Unfortunately, the majority of the genetic studies have been performed in Europeans. The underrepresentation of ethnically diverse populations hinders our ability to completely comprehend the genetic architecture of complex traits and human disease, thereby worsening health inequalities in the underrepresented populations.

In this Research Topic, we are seeking high-quality Original Research and Review papers describing the genetics of diseases in understudied populations. These include African, Latin American, Indian and other indigenous populations. The specific themes of interest in this special issue include but not limited to:
- Genome-wide association studies;
- Gene-environment interactions;
- Polygenic/Genetic Risk Scores;
- Epigenetics;
- Pharmacogenomics;
- Microbiome studies.

Our genes play a role in the occurrence of diseases and the characteristics of complex traits. An understanding of the interplay of these genes and environmental factors is essential for the development of effective therapeutic approaches for the management of diseases. Unfortunately, the majority of the genetic studies have been performed in Europeans. The underrepresentation of ethnically diverse populations hinders our ability to completely comprehend the genetic architecture of complex traits and human disease, thereby worsening health inequalities in the underrepresented populations.

In this Research Topic, we are seeking high-quality Original Research and Review papers describing the genetics of diseases in understudied populations. These include African, Latin American, Indian and other indigenous populations. The specific themes of interest in this special issue include but not limited to:
- Genome-wide association studies;
- Gene-environment interactions;
- Polygenic/Genetic Risk Scores;
- Epigenetics;
- Pharmacogenomics;
- Microbiome studies.

Download ebook

Share

Editors

Queen Mary University of London

Tinashe Chikowore

University of the Witwatersrand

Karoline Kuchenbaecker

University College London

Impact

52,533 Total views

38,743 Article views

12,025 Article downloads

1,765 Topic views

Published In

Journal Thumbnail

Frontiers in Genetics

Genetics of Common and Rare Diseases

Journal Thumbnail

Frontiers in Pediatrics

Genetics of Common and Rare Diseases

About Frontiers Research Topics

With their unique mixes of varied contributions from Original Research to Review Articles, Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author.

Suggest a topic