Research Topic

Nanotoxicology: Challenges and Solutions to Safeguard Human Health and the Environment

About this Research Topic

Undoubtedly, nanotechnology is well established in everyday life as denoted by the great variety of products that contain engineered nanomaterials (ENMs). The release of ENMs and particles to different environmental matrices (water, air, soil) has been demonstrated during the life cycle of consumer products. ...

Undoubtedly, nanotechnology is well established in everyday life as denoted by the great variety of products that contain engineered nanomaterials (ENMs). The release of ENMs and particles to different environmental matrices (water, air, soil) has been demonstrated during the life cycle of consumer products. Consequently, both intentional and unintentional exposure to ENMs have raised concern about their potentially harmful effects on living organisms, including humans, from which emerged the recent research area of nanotoxicology. In this way, different characteristics of the ENMs (i.e. size, shape, charge, chemical composition) have been linked to toxicological effects. Moreover, ENMs can cause toxicity through different mechanisms, ranging from the simple physical adsorption, to the biological surface, to the triggering of complex processes that lead to oxidative stress. Recently, design approaches are gaining importance in the field of nanotechnology with the aim to develop safe and sustainable products.

This Research Topic aims to gather information on the challenges and solutions of the safety by design approach in nanotechnology, with particular emphasis on using nanotoxicology. Therefore, it is intended to present the latest advances to analyze and minimize any toxicological risk to humans and the environment, while maintaining all the properties and characteristics of the ENMs themselves. By bridging the gap between human and environmental nanotoxicology, this Research Topic aims to generate the basis of a reliable discussion of nanomaterial risk assessment along with different biological systems to ensure the safe use of nanotechnology.

This Research Topic welcomes papers on, but not limited to, the following topics:

• Nanotoxicology
• Safety by design approach in nanotechnology
• Harmful effects on living organisms including humans
• Nanoecotoxicology
• Nanomaterials risk assessment

Important Note: All submissions/contributions to this Research Topic must be in line with the scope of the journal/section they are submitted to. While authors are encouraged to draw from other disciplines to enrich their papers where relevant, they must ensure papers fall within the scope of the journal/section, as expressed in its mission statement.

Professor Martin Desimone holds several patent applications and is a founding member of the start-up enterprise Hybridon. All other Topic Editors declare no competing interests with regard to the Research Topic subject.


Keywords: Nanotoxicity, Human and Environmental Impacts, Nanosafety, Nanoecotoxicity, Safety by Design


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

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Submission Deadlines

15 May 2021 Manuscript

Participating Journals

Manuscripts can be submitted to this Research Topic via the following journals:

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Topic Editors

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Submission Deadlines

15 May 2021 Manuscript

Participating Journals

Manuscripts can be submitted to this Research Topic via the following journals:

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