Wound healing on the skin can be difficult for the aging population and patients with underlying conditions, (e.g. diabetes mellitus), as the healing process is significantly delayed. Although traditional drugs exhibit certain effectiveness, it is still far from reaching acceptable therapeutic efficacy. Recently, biomaterials (e.g., hyaluronic acid and collagen) and biotechnologies (e.g., 3D bioprinting, electrospinning) have demonstrated to be important in treating skin wounds, as they can facilitate the transdermal delivery of the drugs, prolong their therapeutic window, and ameliorate the wound microenvironment. Therefore, the development of advanced materials and technologies for effective wound healing has attracted increasing interest.
We aim to seek effective materials for skin treatment, such as targeted materials, intelligent stimuli-responsive materials, bioinspired and biomimetic materials, and to investigate the way they may benefit the skin wounds. Especially, the interaction at the interface between the materials and skin tissues will also be expected to be studied to find out the underlying mechanism of the materials in improving the wounds, which will guide the future design of more advanced materials for wound treatments. Moreover, we also seek advanced technologies, including 3D bioprinting, electrospinning, microfluidics, and microneedles, which are expected to work out the critical issues involved in the wound treatments such as the limitations in transdermal delivery, the lack of maintaining cell viability, the incapability for sustained drug release, and the limited understanding of cellular and molecular cues for wound repair. Therefore, a sufficient study that involves novel design for ideal materials or technologies, as well as the precise underlying mechanisms, will be highly encouraged.
- Advanced materials for skin treatment (e.g., stimuli-responsive materials, targeted materials, bioinspired materials, biomimetic materials)
- Advanced technologies for skin treatment (e.g., microneedle, microfluidics, electrospinning, 3D bioprinting, layer-by-layer strategy)
- Crosstalk between applied materials and skin components (cells, cytokines, ECM, etc.)
Full research articles, letters, highlights, reviews, and mini-reviews are all welcome contributions to this Research Topic.
Wound healing on the skin can be difficult for the aging population and patients with underlying conditions, (e.g. diabetes mellitus), as the healing process is significantly delayed. Although traditional drugs exhibit certain effectiveness, it is still far from reaching acceptable therapeutic efficacy. Recently, biomaterials (e.g., hyaluronic acid and collagen) and biotechnologies (e.g., 3D bioprinting, electrospinning) have demonstrated to be important in treating skin wounds, as they can facilitate the transdermal delivery of the drugs, prolong their therapeutic window, and ameliorate the wound microenvironment. Therefore, the development of advanced materials and technologies for effective wound healing has attracted increasing interest.
We aim to seek effective materials for skin treatment, such as targeted materials, intelligent stimuli-responsive materials, bioinspired and biomimetic materials, and to investigate the way they may benefit the skin wounds. Especially, the interaction at the interface between the materials and skin tissues will also be expected to be studied to find out the underlying mechanism of the materials in improving the wounds, which will guide the future design of more advanced materials for wound treatments. Moreover, we also seek advanced technologies, including 3D bioprinting, electrospinning, microfluidics, and microneedles, which are expected to work out the critical issues involved in the wound treatments such as the limitations in transdermal delivery, the lack of maintaining cell viability, the incapability for sustained drug release, and the limited understanding of cellular and molecular cues for wound repair. Therefore, a sufficient study that involves novel design for ideal materials or technologies, as well as the precise underlying mechanisms, will be highly encouraged.
- Advanced materials for skin treatment (e.g., stimuli-responsive materials, targeted materials, bioinspired materials, biomimetic materials)
- Advanced technologies for skin treatment (e.g., microneedle, microfluidics, electrospinning, 3D bioprinting, layer-by-layer strategy)
- Crosstalk between applied materials and skin components (cells, cytokines, ECM, etc.)
Full research articles, letters, highlights, reviews, and mini-reviews are all welcome contributions to this Research Topic.
