Multiple tissues can be damaged during trauma, including bone, muscle, cartilage, and skin, which provide support, stability, and movement to our body. Severe tissue defect has poor outcomes and current treatment options for tissue regeneration are limited. Nerve regeneration and endothelial regeneration play a critical role in tissue repair, and researchers have done a lot of research in enhancing nerve and vascular regeneration in previous studies. However, the crosstalk between the two in tissue repair and the dynamic changes of the crosstalk at different stages of repair is rarely reported. The major goal of this topic is to accumulate the latest information about neurocyte-endotheliocyte crosstalk during tissue regeneration. To achieve this, a detailed understanding of molecular mechanisms involved in cellular communication and cell differentiation in different research and clinical models is required.
In this research topic, we aim at comprehensive coverage of neurocyte-endotheliocyte crosstalk during tissue regeneration that contributes to cellular communication and cell differentiation. Any kind of articles including research articles, reports, reviews, perspectives and methods potentially covering this intriguing field are welcome.
• New insight on the molecular mechanisms, mechanical stimuli, and bio-nanomaterials for the directional differentiation of stem cells for tissue regeneration
• New molecular mechanism of neurocyte-endotheliocyte crosstalk
• Small extracellular vesicles-based therapeutic strategies in tissue repair and regeneration
• Genetics and Epigenetics in neurocyte-endotheliocyte crosstalk
• The role of small extracellular vesicles in the neurocyte-endotheliocyte crosstalk
• System review of nerve regeneration and angiogenesis during tissue regeneration
Descriptive studies (e.g. gene expression profiles, or transcript, protein, or metabolite levels under particular conditions or in a particular cell type) and studies consisting solely of bioinformatic investigation of publicly available genomic / transcriptomic data do not fall within the scope of the journal unless they are expanded and provide significant biological or mechanistic insight into the process being studied.
Multiple tissues can be damaged during trauma, including bone, muscle, cartilage, and skin, which provide support, stability, and movement to our body. Severe tissue defect has poor outcomes and current treatment options for tissue regeneration are limited. Nerve regeneration and endothelial regeneration play a critical role in tissue repair, and researchers have done a lot of research in enhancing nerve and vascular regeneration in previous studies. However, the crosstalk between the two in tissue repair and the dynamic changes of the crosstalk at different stages of repair is rarely reported. The major goal of this topic is to accumulate the latest information about neurocyte-endotheliocyte crosstalk during tissue regeneration. To achieve this, a detailed understanding of molecular mechanisms involved in cellular communication and cell differentiation in different research and clinical models is required.
In this research topic, we aim at comprehensive coverage of neurocyte-endotheliocyte crosstalk during tissue regeneration that contributes to cellular communication and cell differentiation. Any kind of articles including research articles, reports, reviews, perspectives and methods potentially covering this intriguing field are welcome.
• New insight on the molecular mechanisms, mechanical stimuli, and bio-nanomaterials for the directional differentiation of stem cells for tissue regeneration
• New molecular mechanism of neurocyte-endotheliocyte crosstalk
• Small extracellular vesicles-based therapeutic strategies in tissue repair and regeneration
• Genetics and Epigenetics in neurocyte-endotheliocyte crosstalk
• The role of small extracellular vesicles in the neurocyte-endotheliocyte crosstalk
• System review of nerve regeneration and angiogenesis during tissue regeneration
Descriptive studies (e.g. gene expression profiles, or transcript, protein, or metabolite levels under particular conditions or in a particular cell type) and studies consisting solely of bioinformatic investigation of publicly available genomic / transcriptomic data do not fall within the scope of the journal unless they are expanded and provide significant biological or mechanistic insight into the process being studied.
