Biology of Brain Disorders

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Editorial

21 November 2017

Editorial: Biology of Brain Disorders

Daniela Tropea

and

Andrew Harkin

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3 citations

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2

Daniela Tropea

Trinity College Dublin

Andrew Harkin

Trinity College Dublin

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Brain disorders, including neurological and neuropsychiatric conditions, represent a challenge for public health systems and society at large. The limited knowledge of their biology hampers the development of diagnostic tools and effective therapeutics. A clear understanding of the mechanisms that underlie the onset and progression of brain disorders is required in order to identify new avenues for therapeutic intervention.

Overlapping genetic risk factors across different brain disorders suggest common linkages and pathophysiological mechanisms that underlie brain disorders. Methodological and technological advances are leading to new insights that go beyond traditional hypotheses. Taking account of underlying molecular, cellular and systems biology underlying brain function will play an important role in the classification of brain disorders in future.

In this Research Topic the latest advances in our understanding of biological mechanisms across different brain disorders will be presented. The areas covered include developments in neurogenetics, epigenetics, plasticity, glial cell biology, neuroimmune interactions and new technologies associated with the study of brain function. Examples of how understanding of biological mechanisms are translating into research strategies that aim to advance diagnoses and treatment of brain disorders will be discussed.

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Editors

Daniela Tropea

Trinity College Dublin

Andrew Harkin

Trinity College Dublin

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423,683 Total views

328,954 Article views

79,931 Article downloads

14,798 Topic views

Published In

Frontiers in Cellular Neuroscience

Cellular Neuroscience Archive, Non-Neuronal Cells, Cellular Neurophysiology, Cellular Neuropathology

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Neuroendocrine Science

Frontiers in Molecular Neuroscience

Molecular Neuroscience Archive, Brain Disease Mechanisms, Molecular Signalling and Pathways, Methods and Model Organisms, Neuroplasticity and Development

Frontiers in Genetics

Neurogenomics, Systems Biology Archive

Frontiers in Neuroscience

Neurogenomics, Neurogenesis, Neurodegeneration, Neuroendocrine Science, Neuroenergetics and Brain Health, Systems Biology Archive

Frontiers in Aging Neuroscience

Neuroinflammation and Neuropathy, Alzheimer's Disease and Related Dementias, Neurocognitive Aging and Behavior, Cellular and Molecular Mechanisms of Brain-aging, Parkinson’s Disease and Aging-related Movement Disorders, Aging Neuroscience Archive

Frontiers in Psychiatry

Neurodegeneration, Systems Biology Archive

Frontiers in Neurology

Neurodegeneration, Neurogenomics

Frontiers in Physiology

Systems Biology Archive

Frontiers in Bioengineering and Biotechnology

Systems Biology Archive

Frontiers in Cell and Developmental Biology

Systems Biology Archive

Frontiers in Applied Mathematics and Statistics

Systems Biology Archive

Frontiers in Nutrition

Neuroenergetics and Brain Health

Frontiers in Integrative Neuroscience

Frontiers in Neural Circuits

Frontiers in Synaptic Neuroscience

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