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About this Research Topic

Manuscript Submission Deadline 31 May 2023

Mycotoxins are the toxic secondary metabolites produced by fungi. Twenty-five percent of the global crops are contaminated with mycotoxins before harvesting or during transportation, processing, and storage. Commonly seen foodborne mycotoxins include Aflatoxin, ochratoxin A, patulin, fumonisin, zearalenone, and deoxynivalenol. These mycotoxins contaminate grains, fruits, and their products. Therefore, they harm human health and livestock through daily food and feed intake. The main toxic effects of mycotoxins are immunotoxicity, genotoxicity, carcinogenic teratogenicity, metabolic disorders, damage to intestinal health, and organ damage or functional losses.

This Research Topic will focus on the toxicity of mycotoxins on the immune, metabolic, and gut health of humans and livestock and the in vivo detoxification of mycotoxins. For example, exploring the toxicity and mechanisms of mycotoxins in healthy or diseased individuals and those in specific life stages (such as pregnancy) are welcomed. We also look forward to research achievements on the in vivo detoxification by natural products, nanomaterials, nutritional supplements, or probiotics on mycotoxins from immunity, metabolism, and gut health. We encourage the use of animal tests, in vitro cell experiments, or population investigations.

We accept research articles and reviews on mycotoxins toxicity and in vivo detoxification concerning immune, metabolic, and gut health. We encourage submissions on low-dose mycotoxins safety evaluation modeling and innovative research outcomes that contribute to public health or livestock production such as:

1. Studies on health issues concerning immune, metabolic, and gut health about mycotoxins and their therapies.

2. Establishing connections between target organs when exposed to mycotoxins (e.g., gut-liver axis, gut-brain axis).

3. Studies on toxicity of mycotoxins in specific physiological or diseased populations.

4. Studies on detoxification by natural products, nanomaterials, nutritional supplements, or probiotics on mycotoxins from immunity, metabolism, and gut health mechanism.

Keywords: Mycotoxins, Toxicity, Metabolism, Immunity, Intestinal microorganism, Risk assessment


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

Mycotoxins are the toxic secondary metabolites produced by fungi. Twenty-five percent of the global crops are contaminated with mycotoxins before harvesting or during transportation, processing, and storage. Commonly seen foodborne mycotoxins include Aflatoxin, ochratoxin A, patulin, fumonisin, zearalenone, and deoxynivalenol. These mycotoxins contaminate grains, fruits, and their products. Therefore, they harm human health and livestock through daily food and feed intake. The main toxic effects of mycotoxins are immunotoxicity, genotoxicity, carcinogenic teratogenicity, metabolic disorders, damage to intestinal health, and organ damage or functional losses.

This Research Topic will focus on the toxicity of mycotoxins on the immune, metabolic, and gut health of humans and livestock and the in vivo detoxification of mycotoxins. For example, exploring the toxicity and mechanisms of mycotoxins in healthy or diseased individuals and those in specific life stages (such as pregnancy) are welcomed. We also look forward to research achievements on the in vivo detoxification by natural products, nanomaterials, nutritional supplements, or probiotics on mycotoxins from immunity, metabolism, and gut health. We encourage the use of animal tests, in vitro cell experiments, or population investigations.

We accept research articles and reviews on mycotoxins toxicity and in vivo detoxification concerning immune, metabolic, and gut health. We encourage submissions on low-dose mycotoxins safety evaluation modeling and innovative research outcomes that contribute to public health or livestock production such as:

1. Studies on health issues concerning immune, metabolic, and gut health about mycotoxins and their therapies.

2. Establishing connections between target organs when exposed to mycotoxins (e.g., gut-liver axis, gut-brain axis).

3. Studies on toxicity of mycotoxins in specific physiological or diseased populations.

4. Studies on detoxification by natural products, nanomaterials, nutritional supplements, or probiotics on mycotoxins from immunity, metabolism, and gut health mechanism.

Keywords: Mycotoxins, Toxicity, Metabolism, Immunity, Intestinal microorganism, Risk assessment


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

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