About this Research Topic
Type 2 diabetes accounts for 90 to 95% of all diagnosed cases of diabetes. According to WHO the prevalence of diabetes among adults has risen from 4.7% in 1980 to 8.5% in 2014. According to the CDC in 2012, 25 million American adults (12%) had diabetes and by 2050 the number of Americans with diabetes will jump to 33%. Prediabetes is a condition in which individuals have blood glucose levels that are higher than normal but not high enough to be classified as diabetes. The prevalence of prediabetes among US adults is estimated to be around 38% of the adult population. If diabetes is not controlled within the prediabetic population, this population will become diabetic patients.
Since type 2 diabetes is diet-linked disease, prevention of prediabetes progression to type 2 diabetes can be achieved by appropriate diet and lifestyle interventions. It is reported that plant-derived phytochemicals (such as phenolic compounds, fiber, oligosaccahrides and protein derivatives) may contribute towards type 2 diabetes management by various potential mechanisms. These include regulation of glucose uptake in the small intestine, increasing glucose utilization in the blood or affecting colonic microflora that is linked to high blood glucose levels.
For this Research Topic we welcome scientist to contribute either review or research articles describing the effect of natural products on potential prevention of type 2 diabetes. We welcome any manuscript type, including mechanistic in vitro, animal and clinical.
Keywords: diabetes, clinical, phytochemicals
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