Research Topic

Exercise Shapes up Brain Health

  • Submission closed.

About this Research Topic

Physical exercise (PE) is defined as any planned, structured, and repetitive physical activity that aims to improve or to maintain fitness. There is growing evidence that PE improves brain functions including cognition, memory, motor and emotional behavior. Moreover, PE has been envisioned as a ...

Physical exercise (PE) is defined as any planned, structured, and repetitive physical activity that aims to improve or to maintain fitness. There is growing evidence that PE improves brain functions including cognition, memory, motor and emotional behavior. Moreover, PE has been envisioned as a disease-modifying strategy in neurodegenerative disorders, including Parkinson's and Alzheimer's disease, and as a preventive strategy in age-related CNS maladaptations. Although the mechanisms whereby PE improves neuropsychiatric function are not yet fully understood, the following mechanisms were put forward: a) blunting effect on hormonal stress system (HPA), sympathetic nervous system and immune system; b) increase in number of circulating Tregs and reduction of pro-inflammatory monocytes and macrophages expressing Toll-like receptors; c) decrease of neuroinflammation; d) restoring neuroprotective glia phenotypes; e) increase in expression of neurotrophins and f) enhancing neural plasticity and neurogenesis. Overall, PE is a non-pharmacological intervention which appears to be a very promising approach to the treatment of illness and the promotion of central nervous system (CNS) health.

The current Research Topic focuses on the translational nature of physical exercise within the context of neuropsychiatric health. We are specifically seeking preclinical and translational articles and reviews focused on the involvement of physical exercise in the regulation of:

- Emotional behavior
- Cognition
- Neuroinflammation
- Neuroprotection
- Neurorepair
- Aging


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

Recent Articles

Loading..

About Frontiers Research Topics

With their unique mixes of varied contributions from Original Research to Review Articles, Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author.

Topic Editors

Loading..

Submission Deadlines

Submission closed.

Participating Journals

Loading..

Topic Editors

Loading..

Submission Deadlines

Submission closed.

Participating Journals

Loading..
Loading..

total views article views article downloads topic views

}
 
Top countries
Top referring sites
Loading..

Comments

Loading..

Add a comment

Add comment
Back to top