About this Research Topic
Cancer biologists have the advantage of being able to measure, in exquisite detail, the genetic and protein structure of individual cells and analyze with the full range of tools of bioinformatics. Ecologists generally lack the resources and tools to measure individuals with this resolution, but have the advantage of being able to visit and manipulate their living field site and have thus developed a set of experimental and modeling tools for understanding complex dynamics that far exceed those in cancer biology. These complementary skills point the way to a synthesis of ways to understand the complex ecology of self-organized systems, and this Research Topic will be a chance for ecologists to take the lead in creating this synthesis and open new doors for unified ecological thinking.
This Research Topic seeks to reach across many approaches to show how the successes and failures of cancer biology in using vast quantities of data to understand and predict outcomes has begun to informs multiple fields of ecology:
• the community ecology of diversity and the maintenance and role of heterogeneity in tumors,
• the evolutionary ecology of life history and defensive tradeoffs,
• metabolic and physiological ecology of tumors as consumers of space and resources
• the paleoecology of tumors and the consequences of their distinct modes of evolution.
Keywords: Cancer evolution, Evolutionary ecology, Tumor heterogeneity, Community genetics, Community ecology, Cancer ecology, Tumor evolution, Tumor ecosystem, Population dynamics, Tumor microenvironment
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.