Mechanisms of Innate Neuroprotection

98.6K

views

60

authors

13

articles

Editorial

17 May 2016

Editorial: Mechanisms of Innate Neuroprotection

Giuseppe Pignataro

2,316 views

1 citations

Editors

1

Giuseppe Pignataro

University of Naples Federico II

Impact

About

As clinical trials of pharmacological neuroprotective strategies in stroke have been disappointing, attention has turned to the brain's own endogenous strategies for neuroprotection. Two endogenous mechanisms have been recently characterized, ischemic preconditioning and ischemic postconditioning. In the present topic newly characterized mechanisms involved in preconditioning- and postconditioning- neuroprotection will be discussed. The understanding of the mechanisms involved in the neuroprotective pathways induced by preconditioning and postconditioning will be clinically relevant for identifying new druggable target for neurodegenerative disorder therapy. Furthermore, the importance of these neuroprotective strategies resides in that it might be easily translatable into clinical practice. Therefore, the data presented here will highlight the capacity of ischemic preconditioning and postconditioning to be of benefit to humans.

Download ebook

PDF

EPUB

Share

Editors

Giuseppe Pignataro

University of Naples Federico II

Impact

98,617 Total views

70,913 Article views

24,596 Article downloads

3,108 Topic views

Published In

Frontiers in Neurology

Neurodegeneration

Frontiers in Neuroscience

Neurodegeneration

Frontiers in Psychiatry

Neurodegeneration

About Frontiers Research Topics

With their unique mixes of varied contributions from Original Research to Review Articles, Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author.

Suggest a topic