Research Topic

Quantitative Phase Imaging and Its Applications to Biophysics, Biology, and Medicine

About this Research Topic

Quantitative phase imaging (QPI) exploits the refractive index of biological cells and tissues for imaging, which enables label-free and quantitative assessment of various biological specimens. By addressing the morphology and dynamics of live biological samples with nanoscale sensitivity over temporal scales from milliseconds to days, QPI has shown increasing numbers of applications for the study of the pathophysiology of cells and tissues, with potentials for medical diagnosis as well as industrial applications.

We would like to welcome authors to submit papers for this Research Topic “Quantitative Phase Imaging and Its Applications to Biophysics, Biology, and Medicine”. Papers are solicited on methodologies and applications in the broad area of QPI. Reports on technology development are expected to advance the current state of the art in, for example: new imaging methods, spatial/temporal phase sensitivity, temporal/spatial resolution, tomographic reconstruction, spectroscopic content, throughput, phase reconstruction, phase unwrapping, image processing algorithms, user friendliness, etc.

Reports on applications are expected to target specific biological questions, including: quantifying, monitoring, and functionally assessing the normal and pathological states in live cells and tissues from subcellular to organ scales, encompassing various disciplines of biology and medicine including cell and developmental biology, infectious diseases, cancer biology, neuroscience, microbiology, pharmacology, and pathology.

Topic Editor Prof YongKeun (Paul) Park has financial interest in Tomocube, and Topic Editor Prof. Gabriel Popescu has financial interest in Phi Optics. Both companies commercialize QPI instruments. All other Topic Editors declare no competing interests with regards to the Research Topic subject.


Keywords: Quantitative Phase Imaging, label-free, microscopy, interferometric microscopy, holographic microscopy


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

Quantitative phase imaging (QPI) exploits the refractive index of biological cells and tissues for imaging, which enables label-free and quantitative assessment of various biological specimens. By addressing the morphology and dynamics of live biological samples with nanoscale sensitivity over temporal scales from milliseconds to days, QPI has shown increasing numbers of applications for the study of the pathophysiology of cells and tissues, with potentials for medical diagnosis as well as industrial applications.

We would like to welcome authors to submit papers for this Research Topic “Quantitative Phase Imaging and Its Applications to Biophysics, Biology, and Medicine”. Papers are solicited on methodologies and applications in the broad area of QPI. Reports on technology development are expected to advance the current state of the art in, for example: new imaging methods, spatial/temporal phase sensitivity, temporal/spatial resolution, tomographic reconstruction, spectroscopic content, throughput, phase reconstruction, phase unwrapping, image processing algorithms, user friendliness, etc.

Reports on applications are expected to target specific biological questions, including: quantifying, monitoring, and functionally assessing the normal and pathological states in live cells and tissues from subcellular to organ scales, encompassing various disciplines of biology and medicine including cell and developmental biology, infectious diseases, cancer biology, neuroscience, microbiology, pharmacology, and pathology.

Topic Editor Prof YongKeun (Paul) Park has financial interest in Tomocube, and Topic Editor Prof. Gabriel Popescu has financial interest in Phi Optics. Both companies commercialize QPI instruments. All other Topic Editors declare no competing interests with regards to the Research Topic subject.


Keywords: Quantitative Phase Imaging, label-free, microscopy, interferometric microscopy, holographic microscopy


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

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Submission Deadlines

30 January 2019 Manuscript

Participating Journals

Manuscripts can be submitted to this Research Topic via the following journals:

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Topic Editors

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Submission Deadlines

30 January 2019 Manuscript

Participating Journals

Manuscripts can be submitted to this Research Topic via the following journals:

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