Ifn Signature | List of Frontiers open access articles

Original Research

Published on 23 Sep 2022

Assessment of type I interferon signatures in undifferentiated inflammatory diseases: A Japanese multicenter experience

in Autoimmune and Autoinflammatory Disorders

Takayuki Miyamoto
Yoshitaka Honda
Kazushi Izawa
Nobuo Kanazawa
Saori Kadowaki
Hidenori Ohnishi
Masakazu Fujimoto
Naotomo Kambe
Naoya Kase
Takeshi Shiba

Frontiers in Immunology

doi 10.3389/fimmu.2022.905960

10,127 views
18 citations

Original Research

Published on 28 Aug 2023

Transcriptomic profiling and longitudinal study reveal the relationship of anti-MDA5 titer and type I IFN signature in MDA5+ dermatomyositis

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Yan Wang
Hongxia Jia
Wei Li
Hongping Liu
Meng Tu
Jing Li
Jiuling Cheng
Guojun Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2023.1249844

3,756 views
6 citations

Original Research

Published on 20 Mar 2017

Type I Interferon Gene Response Is Increased in Early and Established Rheumatoid Arthritis and Correlates with Autoantibody Production

in Inflammation

Julio E. Castañeda-Delgado
Yadira Bastián-Hernandez
Noe Macias-Segura
David Santiago-Algarra
Jose D. Castillo-Ortiz
Ana L. Alemán-Navarro
Pedro Martínez-Tejada
Leonor Enciso-Moreno
Yolanda Garcia-De Lira
Diana Olguín-Calderón

Frontiers in Immunology

doi 10.3389/fimmu.2017.00285

12,097 views
62 citations

Original Research

Published on 06 Jun 2022

Dynamics of Type I and Type II Interferon Signature Determines Responsiveness to Anti-TNF Therapy in Rheumatoid Arthritis

in Autoimmune and Autoinflammatory Disorders

Takeshi Iwasaki
Ryu Watanabe
Hiromu Ito
Takayuki Fujii
Kenji Okuma
Takuma Oku
Yoshitaka Hirayama
Koichiro Ohmura
Koichi Murata
Kosaku Murakami

Frontiers in Immunology

doi 10.3389/fimmu.2022.901437

9,157 views
23 citations

Original Research

Published on 08 May 2024

Single-cell transcriptomic analysis of hematopoietic progenitor cells from patients with systemic lupus erythematosus reveals interferon-inducible reprogramming in early progenitors

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Anastasia Filia
Ioannis Mitroulis
Catherine Loukogiannaki
Maria Grigoriou
Aggelos Banos
George Sentis
Stavroula Giannouli
Vassiliki Karali
Emmanouil Athanasiadis
Ioannis Kokkinopoulos

Frontiers in Immunology

doi 10.3389/fimmu.2024.1383358

4,776 views
4 citations

Original Research

Published on 16 Jan 2018

Heterogeneity of the Type I Interferon Signature in Rheumatoid Arthritis: A Potential Limitation for Its Use As a Clinical Biomarker

in Molecular Innate Immunity

Javier Rodríguez-Carrio
Mercedes Alperi-López
Patricia López
Francisco J. Ballina-García
Ana Suárez

Frontiers in Immunology

doi 10.3389/fimmu.2017.02007

7,568 views
44 citations

Original Research

Published on 09 May 2023

Type 1 interferon signature in peripheral blood mononuclear cells and monocytes of idiopathic inflammatory myopathy patients with different myositis-specific autoantibodies

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Mengdi Li
Yusheng Zhang
Wenzhe Zhang
Jinlei Sun
Rui Liu
Zhou Pan
Panpan Zhang
Shengyun Liu

Frontiers in Immunology

doi 10.3389/fimmu.2023.1169057

5,542 views
10 citations

Original Research

Published on 31 Jan 2019

The Long Non-coding RNA NRIR Drives IFN-Response in Monocytes: Implication for Systemic Sclerosis

in Cytokines and Soluble Mediators in Immunity

Barbara Mariotti
Nila Hendrika Servaas
Marzia Rossato
Nicola Tamassia
Marco A. Cassatella
Marta Cossu
Lorenzo Beretta
Maarten van der Kroef
Timothy R. D. J. Radstake
Flavia Bazzoni

Frontiers in Immunology

doi 10.3389/fimmu.2019.00100

10,483 views
71 citations

Mini Review

Published on 13 Mar 2023

Targeting intracellular pathways in idiopathic inflammatory myopathies: A narrative review

in Rheumatology

Gaetano La Rocca
Francesco Ferro
Chiara Baldini
Alessandro Libra
Domenico Sambataro
Michele Colaci
Lorenzo Malatino
Stefano Palmucci
Carlo Vancheri
Gianluca Sambataro

Frontiers in Medicine

doi 10.3389/fmed.2023.1158768

5,255 views
9 citations

Original Research

Published on 07 Jan 2019

IRF4 and IRGs Delineate Clinically Relevant Gene Expression Signatures in Systemic Lupus Erythematosus and Rheumatoid Arthritis

in Molecular Innate Immunity

Javier Rodríguez-Carrio
Patricia López
Mercedes Alperi-López
Luis Caminal-Montero
Francisco J. Ballina-García
Ana Suárez

Frontiers in Immunology

doi 10.3389/fimmu.2018.03085

8,691 views
27 citations

Review

Published on 06 Sep 2013

The Role of Type 1 Interferon in Systemic Sclerosis

in Molecular Innate Immunity

Minghua Wu
Shervin Assassi

Frontiers in Immunology

doi 10.3389/fimmu.2013.00266

15,942 views
108 citations

Case Report

Published on 04 Feb 2025

Case report: Exploring efficacy of tofacitinib in modulating interferon response in five case of anti-MDA5+ dermatomyositis with interstitial lung disease

in Cytokines and Soluble Mediators in Immunity

Jie Zhao
Yan Bao
Ying Gao
Keliang Xie

Frontiers in Immunology

doi 10.3389/fimmu.2025.1515602

3,269 views

Original Research

Published on 24 Nov 2023

A zebrafish model of Ifih1-driven Aicardi–Goutières syndrome reproduces the interferon signature and the exacerbated inflammation of patients

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Beatriz Bernal-Bermúdez
Alicia Martínez-López
Francisco J. Martínez-Morcillo
Sylwia D. Tyrkalska
Teresa Martínez-Menchón
Pablo Mesa-del-Castillo
María L. Cayuela
Victoriano Mulero
Diana García-Moreno

Frontiers in Immunology

doi 10.3389/fimmu.2023.1294766

4,175 views
2 citations

Original Research

Published on 28 Jan 2022

High Interferon Signature Leads to Increased STAT1/3/5 Phosphorylation in PBMCs From SLE Patients by Single Cell Mass Cytometry

in Autoimmune and Autoinflammatory Disorders

Gloria Yiu
Tue Kruse Rasmussen
Brandon L. Tsai
Vivian K. Diep
David J. Haddon
Jennifer Tsoi
Gopika D. Miller
Begoña Comin-Anduix
Bent Deleuran
Gay M. Crooks

Frontiers in Immunology

doi 10.3389/fimmu.2022.833636

12,383 views
15 citations

Mini Review

Published on 15 Jul 2022

Type-I Interferons in Alzheimer's Disease and Other Tauopathies

in Non-Neuronal Cells

Sophie A. I. Sanford
William A. McEwan

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2022.949340

10,024 views
29 citations

Original Research

Published on 07 Apr 2025

Type I IFN receptor blockade alleviates liver fibrosis through macrophage-derived STAT3 signaling

in Mucosal Immunity

Soo-Jeung Park
Josefina Garcia Diaz
Tina Comlekoglu
Young S. Hahn

Frontiers in Immunology

doi 10.3389/fimmu.2025.1528382

4,056 views

Articles

Assessment of type I interferon signatures in undifferentiated inflammatory diseases: A Japanese multicenter experience

Transcriptomic profiling and longitudinal study reveal the relationship of anti-MDA5 titer and type I IFN signature in MDA5+ dermatomyositis

Type I Interferon Gene Response Is Increased in Early and Established Rheumatoid Arthritis and Correlates with Autoantibody Production

Dynamics of Type I and Type II Interferon Signature Determines Responsiveness to Anti-TNF Therapy in Rheumatoid Arthritis

Single-cell transcriptomic analysis of hematopoietic progenitor cells from patients with systemic lupus erythematosus reveals interferon-inducible reprogramming in early progenitors

Heterogeneity of the Type I Interferon Signature in Rheumatoid Arthritis: A Potential Limitation for Its Use As a Clinical Biomarker

Type 1 interferon signature in peripheral blood mononuclear cells and monocytes of idiopathic inflammatory myopathy patients with different myositis-specific autoantibodies

The Long Non-coding RNA NRIR Drives IFN-Response in Monocytes: Implication for Systemic Sclerosis

Targeting intracellular pathways in idiopathic inflammatory myopathies: A narrative review

IRF4 and IRGs Delineate Clinically Relevant Gene Expression Signatures in Systemic Lupus Erythematosus and Rheumatoid Arthritis

The Role of Type 1 Interferon in Systemic Sclerosis

Case report: Exploring efficacy of tofacitinib in modulating interferon response in five case of anti-MDA5+ dermatomyositis with interstitial lung disease

A zebrafish model of Ifih1-driven Aicardi–Goutières syndrome reproduces the interferon signature and the exacerbated inflammation of patients

High Interferon Signature Leads to Increased STAT1/3/5 Phosphorylation in PBMCs From SLE Patients by Single Cell Mass Cytometry

Type-I Interferons in Alzheimer's Disease and Other Tauopathies

Type I IFN receptor blockade alleviates liver fibrosis through macrophage-derived STAT3 signaling