Pharmacophore | List of Frontiers open access articles

Original Research

Published on 03 Nov 2025

Mechanism of active component β-sitosterol from Myristica fragrans inducing apoptosis in bladder cancer cells via regulating the BCL-2/BAX/caspase-3 pathway

in Pharmacology of Anti-Cancer Drugs

Yongkang Zhu
Zhao Tang
Zhaoyue Lu
Dongyang Gao
Hao Pan
Haozhe Jiang
Zhen Zhang
Huiqing Zhang

Frontiers in Oncology

doi 10.3389/fonc.2025.1698721

296 views

Original Research

Published on 03 Nov 2025

Psychological predictors of sports injuries in elite sky athletes: a multidimensional analysis of personality, anxiety, depression and inflexibility

in Sport Psychology

Sara Mogedano-Cruz
Vicente Javier Clemente-Suárez
Rafael Jácome-López
Fernando García-Sanz
Laura González-Fernández
Ángel González-de-la-Flor
Carlos Romero-Morales

Frontiers in Psychology

doi 10.3389/fpsyg.2025.1698313

408 views

Review

Published on 03 Nov 2025

Primary biliary cholangitis. Treatment options in 2025. A narrative review

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Maria Angelara
Klairi Papachristou
Margarita Papatheodoridi
Narjes Nasiri-Ansari
Dimitrios S. Karagiannakis
Theodoros Androutsakos

Frontiers in Immunology

doi 10.3389/fimmu.2025.1698833

481 views

Editorial

Published on 03 Nov 2025

Editorial: Women in malaria research

in Pathogenesis

Alena Pance
Elena Gómez-Díaz
Sarah Reece

Frontiers in Malaria

doi 10.3389/fmala.2025.1725748

672 views

Original Research

Published on 03 Nov 2025

The global burden, trends and cross-region inequities of non-communicable diseases attributed to ambient particulate matter pollution

in Environmental Health and Exposome

Songsong Wang
Hanpeng Lai

Frontiers in Public Health

doi 10.3389/fpubh.2025.1682574

250 views

Original Research

Published on 03 Nov 2025

Burden of chronic obstructive pulmonary disease in Ghana and globally from 1990 to 2021, with projections through 2050: a systematic analysis based on the Global Burden of Disease Study 2021

in Pulmonary Medicine

Emmanuel Mensah
Min Liu
Lingling Pan
Wei Lu
Susheng Zhou
Liqin Zhang
Yusheng Cheng
Shuoshuo Wei
Lei Zha

Frontiers in Medicine

doi 10.3389/fmed.2025.1681411

419 views

Original Research

Published on 03 Nov 2025

Understanding public awareness and knowledge of lung cancer screening practices: a cross-sectional study from the Asir region, Saudi Arabia

in Public Health Education and Promotion

Geetha Kandasamy
Khalid Orayj
Asma M. Alshahrani
Tahani S. Alanazi
Amjad Hmlan
Sitah Alharthi
Hanan Alyami
Arwa Khaled

Frontiers in Public Health

doi 10.3389/fpubh.2025.1678080

144 views

Original Research

Published on 03 Nov 2025

Drivers and impacts of changes in water quality behavior from the Hermit’s Peak—Calf Canyon wildfire

in Environmental Water Quality

Paige Tunby
David J. Van Horn
Ricardo González-Pinzón

Frontiers in Water

doi 10.3389/frwa.2025.1676600

379 views

Original Research

Published on 03 Nov 2025

Impact of different forest types on soil microbial biomass and microbial entropy in the karst region of southwestern China

in Functional Plant Ecology

Yan Wu
Xiaoli Zhong
Xun Liu
Bo Ding
Yunlin Zhang

Frontiers in Plant Science

doi 10.3389/fpls.2025.1678667

192 views

Case Report

Published on 03 Nov 2025

Case Report: Bilateral testicular teratoma in an infant with torsion of an intra-abdominal testis and contralateral testicular teratoma

in Pediatric Oncology

Chaoyang Hua
Hongjie Fan
Zhan Guo
Xing Li
Yanfang Yang
Jianpeng Bi

Frontiers in Pediatrics

doi 10.3389/fped.2025.1680506

193 views

Original Research

Published on 03 Nov 2025

Parametrized statistical appearance and shape modelling strategy to predict proximal and diaphyseal femoral fractures

in Biomechanics

Özgür Cebeci
Duane S. Cronin
Sara Checa

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1693678

463 views

Review

Published on 03 Nov 2025

AI alignment is all your need for future drug discovery

in Medicine and Public Health

Chunyan Li

Frontiers in Artificial Intelligence

doi 10.3389/frai.2025.1668794

584 views

Original Research

Published on 03 Nov 2025

Family-based NGS panel testing of cardiopathies and arrhythmic syndromes

in Genetics of Common and Rare Diseases

Hana Hrazderova
Jana Petrkova
Anna Crhova
Klara Herkommerova
Kvetoslava Mahutova
Julie Nejezchlebova
Lenka Petrkova
Lubos Boucek
Arpad Boday
Spiros Tavandzis

Frontiers in Genetics

doi 10.3389/fgene.2025.1677311

452 views

Brief Research Report

Published on 03 Nov 2025

Correlations between biological markers of the perirenal adipose tissue and clinical features of patients with localized kidney cancer

in Pathology

Leonardo Rafael Romeo
Matías Nuñez
Matías Ferrando
Constanza Matilde López-Fontana
Rubén Walter Carón
Flavia Alejandra Bruna
Virginia Pistone-Creydt

Frontiers in Medicine

doi 10.3389/fmed.2025.1676630

290 views

Review

Published on 03 Nov 2025

Cost analysis and cost-effectiveness of traditional Chinese medicine in lung cancer: a scoping review

in Health Economics

Ran An
Gangqiang Su

Frontiers in Public Health

doi 10.3389/fpubh.2025.1669751

569 views

Original Research

Published on 03 Nov 2025

Real-world insights from acute management of potassium disorders in diabetic ketoacidosis

in Clinical Diabetes

Yue Zhang
Jing Li
Shanshan Deng
Yongjing Zhang
Manli Guo
Fangfang Jiang
Lingguang Luo
Yanqing He
Shaogang Ma
Yigen Peng

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1669400

457 views

Articles

Mechanism of active component β-sitosterol from Myristica fragrans inducing apoptosis in bladder cancer cells via regulating the BCL-2/BAX/caspase-3 pathway

Psychological predictors of sports injuries in elite sky athletes: a multidimensional analysis of personality, anxiety, depression and inflexibility

Primary biliary cholangitis. Treatment options in 2025. A narrative review

Editorial: Women in malaria research

The global burden, trends and cross-region inequities of non-communicable diseases attributed to ambient particulate matter pollution

Burden of chronic obstructive pulmonary disease in Ghana and globally from 1990 to 2021, with projections through 2050: a systematic analysis based on the Global Burden of Disease Study 2021

Understanding public awareness and knowledge of lung cancer screening practices: a cross-sectional study from the Asir region, Saudi Arabia

Drivers and impacts of changes in water quality behavior from the Hermit’s Peak—Calf Canyon wildfire

Impact of different forest types on soil microbial biomass and microbial entropy in the karst region of southwestern China

Case Report: Bilateral testicular teratoma in an infant with torsion of an intra-abdominal testis and contralateral testicular teratoma

Parametrized statistical appearance and shape modelling strategy to predict proximal and diaphyseal femoral fractures

AI alignment is all your need for future drug discovery

Family-based NGS panel testing of cardiopathies and arrhythmic syndromes

Correlations between biological markers of the perirenal adipose tissue and clinical features of patients with localized kidney cancer

Cost analysis and cost-effectiveness of traditional Chinese medicine in lung cancer: a scoping review

Real-world insights from acute management of potassium disorders in diabetic ketoacidosis