Rasrafmekerk Pathway | List of Frontiers open access articles

Review

Published on 24 Jun 2014

Ras/Raf/MEK/ERK Pathway Activation in Childhood Acute Lymphoblastic Leukemia and Its Therapeutic Targeting

in Pediatric Oncology

Thomas Knight
Julie Anne Elizabeth Irving

Frontiers in Oncology

doi 10.3389/fonc.2014.00160

22,536 views
133 citations

Original Research

Published on 10 Jul 2025

A diaryl urea derivative, SMCl inhibits cell proliferation through the RAS/RAF/MEK/ERK pathway in hepatocellular carcinoma

in Experimental Pharmacology and Drug Discovery

Yue Fu
Weiyue Fang
Fuqiang Qiu
Juncai Lai
Yangjin Xu
Bin Chen
Yang Li
Xiaohui Zhu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1605515

1,342 views

Original Research

Published on 20 May 2022

Design, Synthesis, and Antileukemic Evaluation of a Novel Mikanolide Derivative Through the Ras/Raf/MEK/ERK Pathway

in Pharmacology of Anti-Cancer Drugs

Qing Rao
Kaiqiang Xie
Krishnapriya M. Varier
Lei Huang
Jingrui Song
Jue Yang
Jianfei Qiu
Yubing Huang
Yan Li
Babu Gajendran

Frontiers in Pharmacology

doi 10.3389/fphar.2022.809551

3,709 views
1 citation

Review

Published on 06 Oct 2021

Everything Old Is New Again: Drug Repurposing Approach for Non-Small Cell Lung Cancer Targeting MAPK Signaling Pathway

in Cancer Molecular Targets and Therapeutics

Anisha S. Jain
Ashwini Prasad
Sushma Pradeep
Chandan Dharmashekar
Raghu Ram Achar
Ekaterina Silina
Victor Stupin
Raghavendra G. Amachawadi
Shashanka K. Prasad
R Pruthvish

Frontiers in Oncology

doi 10.3389/fonc.2021.741326

16,193 views
38 citations

Mini Review

Published on 15 Nov 2013

Toward a Molecular Classification of Colorectal Cancer: The Role of BRAF

in Gastrointestinal Cancers

Alexandra Thiel
Ari Ristimäki

Frontiers in Oncology

doi 10.3389/fonc.2013.00281

15,705 views
56 citations

Original Research

Published on 08 Apr 2019

A YWHAZ Variant Associated With Cardiofaciocutaneous Syndrome Activates the RAF-ERK Pathway

in Developmental Physiology

Ivan K. Popov
Susan M. Hiatt
Sandra Whalen
Boris Keren
Claudia Ruivenkamp
Arie van Haeringen
Mei-Jan Chen
Gregory M. Cooper
Bruce R. Korf
Chenbei Chang

Frontiers in Physiology

doi 10.3389/fphys.2019.00388

8,945 views
36 citations

Articles

Ras/Raf/MEK/ERK Pathway Activation in Childhood Acute Lymphoblastic Leukemia and Its Therapeutic Targeting

A diaryl urea derivative, SMCl inhibits cell proliferation through the RAS/RAF/MEK/ERK pathway in hepatocellular carcinoma

Design, Synthesis, and Antileukemic Evaluation of a Novel Mikanolide Derivative Through the Ras/Raf/MEK/ERK Pathway

Everything Old Is New Again: Drug Repurposing Approach for Non-Small Cell Lung Cancer Targeting MAPK Signaling Pathway

Toward a Molecular Classification of Colorectal Cancer: The Role of BRAF

A YWHAZ Variant Associated With Cardiofaciocutaneous Syndrome Activates the RAF-ERK Pathway