Sophora Flavescens | List of Frontiers open access articles

Original Research

Published on 14 Oct 2021

Construction of a “Bacteria-Metabolites” Co-Expression Network to Clarify the Anti–Ulcerative Colitis Effect of Flavonoids of Sophora flavescens Aiton by Regulating the “Host–Microbe” Interaction

in Ethnopharmacology

Jing Shao
Zhaocheng Li
Yanping Gao
Kairui Zhao
Minling Lin
Yadi Li
Shumei Wang
Yi Liu
Lei Chen

Frontiers in Pharmacology

doi 10.3389/fphar.2021.710052

8,231 views
47 citations

Systematic Review

Published on 19 Nov 2024

Meta-analysis of the effect of sophora flavescens on tumor metastasis-induced bone neuropathic pain

in Ethnopharmacology

Cheng Chang
Di Sun
Zhilei Zhang
Lei He
Qiang Wang
Yingchao Shen
Hengzhou Zhu
Donghua Fan

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1474982

2,077 views

Review

Published on 07 May 2020

Matrine: A Promising Natural Product With Various Pharmacological Activities

in Ethnopharmacology

Hong Zhang
Linlin Chen
Xipeng Sun
Quanjun Yang
Lili Wan
Cheng Guo

Frontiers in Pharmacology

doi 10.3389/fphar.2020.00588

27,946 views
133 citations

Original Research

Published on 10 Jul 2024

Prenylated flavonoids from Sophora flavescens inhibit mushroom tyrosinase activity and modulate melanogenesis in murine melanoma cells and zebrafish

in Ethnopharmacology

Fenling Fan
Lanqing Chen
Caihong Chen
Song Ang
Justin Gutkowski
Navindra P. Seeram
Hang Ma
Dongli Li

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1422310

2,921 views
1 citation

Original Research

Published on 24 Sep 2024

Comparative genomics and transcriptomics analysis of the bHLH gene family indicate their roles in regulating flavonoid biosynthesis in Sophora flavescens

in Plant Metabolism and Chemodiversity

Ake Liu
Junjie Lu
Huifang Song
Xi Wang
Mingyang Wang
Zhenhong Lei
Huixuan Liu
Haiying Lei
Tianzeng Niu

Frontiers in Plant Science

doi 10.3389/fpls.2024.1445488

2,182 views
6 citations

Review

Published on 29 Apr 2024

A review on the pharmacology, pharmacokinetics and toxicity of sophocarpine

in Ethnopharmacology

Shichao Wei
Junshen Xiao
Feng Ju
Jin Liu
Zhaoyang Hu

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1353234

4,873 views
12 citations

Original Research

Published on 14 Jan 2016

The Extract of Roots of Sophora flavescens Enhances the Recovery of Motor Function by Axonal Growth in Mice with a Spinal Cord Injury

in Ethnopharmacology

Norio Tanabe
Tomoharu Kuboyama
Kohei Kazuma
Katsuhiro Konno
Chihiro Tohda

Frontiers in Pharmacology

doi 10.3389/fphar.2015.00326

9,066 views
20 citations

Original Research

Published on 14 Dec 2021

Taxonomic Structure of Rhizosphere Bacterial Communities and Its Association With the Accumulation of Alkaloidal Metabolites in Sophora flavescens

in Terrestrial Microbiology

Jie Chen
Na Li
Jiayu Chang
Kaida Ren
Jiangtao Zhou
Guan’e Yang

Frontiers in Microbiology

doi 10.3389/fmicb.2021.781316

3,448 views
11 citations

Original Research

Published on 26 Apr 2019

Effect of Compound Kushen Injection, a Natural Compound Mixture, and Its Identified Chemical Components on Migration and Invasion of Colon, Brain, and Breast Cancer Cell Lines

in Pharmacology of Anti-Cancer Drugs

Saeed Nourmohammadi
Thazin Nwe Aung
Jian Cui
Jinxin V. Pei
Michael Lucio De Ieso
Yuka Harata-Lee
Zhipeng Qu
David L. Adelson
Andrea J. Yool

Frontiers in Oncology

doi 10.3389/fonc.2019.00314

9,390 views
52 citations

Original Research

Published on 23 Dec 2024

Genome-wide identification and expression analysis of the WRKY gene family in Sophora flavescens during tissue development and salt stress

in Functional and Applied Plant Genomics

Jin Li
Xi Wang
Junjie Lu
Huifang Song
Haiying Lei
Tianzeng Niu
Ake Liu

Frontiers in Plant Science

doi 10.3389/fpls.2024.1520786

1,591 views
1 citation

Original Research

Published on 16 Nov 2021

A System Pharmacology Model for Decoding the Synergistic Mechanisms of Compound Kushen Injection in Treating Breast Cancer

in Pharmacology of Anti-Cancer Drugs

Yi Li
Kexin Wang
Yupeng Chen
Jieqi Cai
Xuemei Qin
Aiping Lu
Daogang Guan
Genggeng Qin
Weiguo Chen

Frontiers in Pharmacology

doi 10.3389/fphar.2021.723147

6,212 views
2 citations

Original Research

Published on 28 Nov 2019

Matrine Reverses the Warburg Effect and Suppresses Colon Cancer Cell Growth via Negatively Regulating HIF-1α

in Pharmacology of Anti-Cancer Drugs

Xiaoting Hong
Linhai Zhong
Yurou Xie
Kaifeng Zheng
Jinglong Pang
Yesen Li
Yifan Yang
Xiaolin Xu
Panying Mi
Hanwei Cao

Frontiers in Pharmacology

doi 10.3389/fphar.2019.01437

7,727 views
49 citations

Original Research

Published on 31 May 2021

Oxymatrine Attenuates Osteoclastogenesis via Modulation of ROS-Mediated SREBP2 Signaling and Counteracts Ovariectomy-Induced Osteoporosis

in Molecular and Cellular Pathology

Chao Jiang
Qingliang Ma
Shiyu Wang
Yang Shen
An Qin
Shunwu Fan
Zhiwei Jie

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2021.684007

5,456 views
18 citations

Review

Published on 16 Sep 2020

A Systematic Review of the Pharmacology, Toxicology and Pharmacokinetics of Matrine

in Ethnopharmacology

Longtai You
Chunjing Yang
Yuanyuan Du
Wenping Wang
Mingyi Sun
Jing Liu
Baorui Ma
Linnuo Pang
Yawen Zeng
Zhiqin Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2020.01067

15,309 views
92 citations

Original Research

Published on 13 Apr 2021

Neuroprotective Effects of Oxymatrine on PI3K/Akt/mTOR Pathway After Hypoxic-Ischemic Brain Damage in Neonatal Rats

in Neuropharmacology

Wei Wei
Min Lu
Xiao-bing Lan
Ning Liu
Wei-ke Su
Alexandr V. Dushkin
Jian-qiang Yu

Frontiers in Pharmacology

doi 10.3389/fphar.2021.642415

5,010 views
28 citations

Original Research

Published on 24 Apr 2018

Sophora flavescens Aiton Decreases MPP+-Induced Mitochondrial Dysfunction in SH-SY5Y Cells

in Cellular and Molecular Mechanisms of Brain-aging

Hee-Young Kim
Hyongjun Jeon
Hyungwoo Kim
Sungtae Koo
Seungtae Kim

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2018.00119

10,692 views
29 citations

Articles

Construction of a “Bacteria-Metabolites” Co-Expression Network to Clarify the Anti–Ulcerative Colitis Effect of Flavonoids of Sophora flavescens Aiton by Regulating the “Host–Microbe” Interaction

Meta-analysis of the effect of sophora flavescens on tumor metastasis-induced bone neuropathic pain

Matrine: A Promising Natural Product With Various Pharmacological Activities

Prenylated flavonoids from Sophora flavescens inhibit mushroom tyrosinase activity and modulate melanogenesis in murine melanoma cells and zebrafish

Comparative genomics and transcriptomics analysis of the bHLH gene family indicate their roles in regulating flavonoid biosynthesis in Sophora flavescens

A review on the pharmacology, pharmacokinetics and toxicity of sophocarpine

The Extract of Roots of Sophora flavescens Enhances the Recovery of Motor Function by Axonal Growth in Mice with a Spinal Cord Injury

Taxonomic Structure of Rhizosphere Bacterial Communities and Its Association With the Accumulation of Alkaloidal Metabolites in Sophora flavescens

Effect of Compound Kushen Injection, a Natural Compound Mixture, and Its Identified Chemical Components on Migration and Invasion of Colon, Brain, and Breast Cancer Cell Lines

Genome-wide identification and expression analysis of the WRKY gene family in Sophora flavescens during tissue development and salt stress

A System Pharmacology Model for Decoding the Synergistic Mechanisms of Compound Kushen Injection in Treating Breast Cancer

Matrine Reverses the Warburg Effect and Suppresses Colon Cancer Cell Growth via Negatively Regulating HIF-1α

Oxymatrine Attenuates Osteoclastogenesis via Modulation of ROS-Mediated SREBP2 Signaling and Counteracts Ovariectomy-Induced Osteoporosis

A Systematic Review of the Pharmacology, Toxicology and Pharmacokinetics of Matrine

Neuroprotective Effects of Oxymatrine on PI3K/Akt/mTOR Pathway After Hypoxic-Ischemic Brain Damage in Neonatal Rats

Sophora flavescens Aiton Decreases MPP+-Induced Mitochondrial Dysfunction in SH-SY5Y Cells