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Review ARTICLE Provisionally accepted The full-text will be published soon. Notify me

Front. Integr. Neurosci. | doi: 10.3389/fnint.2019.00047

Effects of Acupuncture on Neurological disease in Clinical- and Animal-Based Research

Xiangyu Guo1 and  Tao Ma1*
  • 1Dongfang Hospital, China

Neurological disease, including Alzheimer’s disease (AD), Parkinson’s disease (PD), which were caused by abnormalities in the nervous system, involves the accumulation of false proteins, neurotransmitter abnormalities, neuronal apoptosis, etc. As an alternative supplementary medicine (ASM), acupuncture plays an important role in the treatment of neurological diseases. In this review, we summarized the current evidence for the treatment efficacy of acupuncture in AD and PD from the perspective of clinical trials and animal model. Acupuncture can inhibit the accumulation of toxic proteins in neurological diseases, modulate energy supply based on glucose metabolism, depress neuronal apoptosis, etc., and exert a wide range of neuroprotective effects.

Keywords: Neurological Disease, Alzheimer ' s disease, Parkinson ’s disease, Clinical Trial, animal model, Acupunture

Received: 31 May 2019; Accepted: 12 Aug 2019.

Edited by:

Xiaodong Liu, Beijing University of Chinese Medicine, China

Reviewed by:

Jinhai Huo, University of Florida, United States
Wensheng Zhang, Beijing Normal University, China
Chunhe Wang, Shanghai Institute of Materia Medica,Chinese Academy of Sciences, China  

Copyright: © 2019 Guo and Ma. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Mx. Tao Ma, Dongfang Hospital, Fengtai, 100078, Beijing, China, matao327@126.com