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REVIEW article
Front. Physiol.
Sec. Integrative Physiology
Volume 15 - 2024 |
doi: 10.3389/fphys.2024.1393000
This article is part of the Research Topic 73rd Annual Meeting of the Italian Society of Physiology: Advancement in Basic and Translational Physiology View all 5 articles
Intrinsic Organization of the Corpus Callosum
Provisionally accepted- 1 Marche Polytechnic University, Ancona, Marche, Italy
- 2 Marche University Hospital, Ancona, Marche, Italy
The corpus callosum - the largest commissural fiber system connecting the two hemispheres – is considered essential for bilateral sensory integration and higher cognitive functions. Most studies exploring the corpus callosum have examined either the anatomical, physiological and neurochemical organization of callosal projections or the functional and/or behavioral aspects of the callosal connections after complete/partial callosotomy or callosal lesion. There are no works addressing the intrinsic organization of the corpus callosum. We review the existing information on the activities that take place in the commissure in three sections: I) topographical and neurochemical organization of intracallosal fibers; II) role of glia in the corpus callosum; and III) role of intracallosal neurons.
Keywords: nNOS, NADPHd, NK1, aspartate, Glutamate, GluRs, GlutTs, VGLUTs
Received: 28 Feb 2024; Accepted: 16 May 2024.
Copyright: © 2024 Barbaresi, Fabri, Lorenzi, Sagrati and Morroni. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Paolo Barbaresi, Marche Polytechnic University, Ancona, 60121, Marche, Italy
Mara Fabri, Marche Polytechnic University, Ancona, 60121, Marche, Italy
Andrea Sagrati, Marche Polytechnic University, Ancona, 60121, Marche, Italy
Manrico Morroni, Marche University Hospital, Ancona, 60126, Marche, Italy
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