Exosomes - nano-sized extracellular vesicles - have emerged as powerful tools in biomedical research and therapeutics due to their ability to transfer specific cellular components to recipient cells.
Explore the following trending articles in Frontiers in Bioengineering and Biotechnology and Frontiers in Drug Delivery.
This article overviews exosomal properties, biogenesis, contents, and functions, outlines the conventional technologies and their clinical applications challenges, and reviews emerging exosomal isolation strategies.
This review article discusses the regulatory role of potential microRNA biomarkers and related therapeutic targets on the blood-brain barrier.
This research article investigates a treatment for retinitis pigmentosa using optogenetics and CRISPR/Cas technology to restore light sensitivity in remaining retinal cells.
Delivering the NR2B9c and N-dimer peptides to the brain could treat ischemic stroke, however it is challenging due to the blood-brain barrier. This study. This study focuses on finding a way to deliver them by attaching them to the Tat peptide.
This review discusses the blood–brain barrier structural and functional resistance, as well as potential avenues to overcome this challenge using extracellular vesicles as drug delivery vehicles into the brain.
Biologics are at the forefront of central nervous system disease treatment. This review discusses how biologics such as peptides and RNA interference agents interact with brain capillary endothelial cells to cross the blood-brain barrier.
Read other impactful articles published in Frontiers in Bioengineering and Biotechnology and Frontiers in Drug Delivery