Ac2o | List of Frontiers open access articles

Review

Published on 07 Nov 2025

DNA methylation and immune regulation in osteoporosis: emerging epigenetic targets for drug discovery

in Experimental Pharmacology and Drug Discovery

Yingli Yang
Yao Yao
Xiaoyu Cai
Yaqi Tao
Zhengbing Zhuge
Jianhong Zhou
Caihong Zheng

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1688305

324 views

Original Research

Published on 07 Nov 2025

Impact of biologic therapy on blood cell indices and exacerbation risk in severe asthma: predictive value of the neutrophil-to-eosinophil ratio

in Mechanisms in Allergy

Mona Al-Ahmad
Asmaa Ali
Wafaa Talat

Frontiers in Allergy

doi 10.3389/falgy.2025.1691886

441 views

Original Research

Published on 07 Nov 2025

Composite shoreline-retreat workflow (CoShReW): a case study on the Andalusian coast

in Coastal Ocean Processes

Arnau Garcia Tort
Paula Gomes da Silva
Erica Pellón
Verónica Cánovas
Mauricio González
Raúl Medina
Antonio Henrique da Fontoura Klein

Frontiers in Marine Science

doi 10.3389/fmars.2025.1695289

814 views

Review

Published on 07 Nov 2025

Dysfunctions of sleep and the circadian rhythm in Huntington’s disease

in Dementia and Neurodegenerative Diseases

Paulina Kaczmarska
Monika Rudzińska-Bar

Frontiers in Neurology

doi 10.3389/fneur.2025.1693307

541 views

Brief Research Report

Published on 07 Nov 2025

Mindfulness training combined with cold water immersion effects on mood and perception of executive functioning in middle-aged and older adults: a pilot study

in Aging and Public Health

Ambra Gentile
Sara Vivirito
Musa Kirkar
Konstantinos Paschos
Luka Tuđan
Jakub Kulhánek
Pelin Öztürk
Marianna Alesi

Frontiers in Public Health

doi 10.3389/fpubh.2025.1693026

302 views

Original Research

Published on 07 Nov 2025

Impact of early vs. delayed intravenous magnesium sulfate on clinical outcomes in pediatric severe asthma: a retrospective cohort study

in Pediatric Emergency Medicine

Mohammid Alzain
Sajjad Alkhadem
Rafa Alotbi
Ibrahim Alammari
Norah Aljabri
Reem Almijlad
Shahd Abureesh
Hadeel Alharbi
Rawan Alrashed
Yara Algoraini

Frontiers in Disaster and Emergency Medicine

doi 10.3389/femer.2025.1689282

611 views

Original Research

Published on 07 Nov 2025

Biomechanical optimization study of posterior tilt extension stems in the repair of tibial plateau bone defects

in Biomechanics

Yong Wang
Ruihu Hao
Lin Guo
Xiaoyu Zhou

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1688915

225 views

Perspective

Published on 07 Nov 2025

The role of early human development and multidimensional enhancements in driving space adaptation and Universal Cognition

in Space Exploration

Marta Ferraz

Frontiers in Space Technologies

doi 10.3389/frspt.2025.1705650

625 views

Correction

Published on 07 Nov 2025

Correction: PFOA biomonitoring and kidney cancer risk: a meta-analysis of serum levels

in Cancer Epidemiology and Prevention

Francesca Spyrakis
Gioele Antonio Tiburtini
Stefania Bruno
Tommaso A. Dragani
Francesca Colombo

Frontiers in Oncology

doi 10.3389/fonc.2025.1705495

123 views

Original Research

Published on 07 Nov 2025

STAT3 as a critical target of Sijunzi Decoction in the treatment of gastric cancer: evidence from integrated network pharmacology and experimental validation

in Molecular Diagnostics and Therapeutics

XiaoYu Luo
GuiPing Xie
QianYing Tan
YaoHui Wang
HaiDan Wang
Jing Zhai

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1683806

350 views

Original Research

Published on 07 Nov 2025

Joint association of indoor allergens, endotoxins, heavy metals, and parabens with allergy-related outcomes in U. S. adults

in Environmental Health and Exposome

Min Xue
Xiaoling Wei
Yun Zhang
Xiang Ma

Frontiers in Public Health

doi 10.3389/fpubh.2025.1683381

519 views

Brief Research Report

Published on 07 Nov 2025

Neuro-functional correlates of personality dimensions in Parkinson’s disease

in Neuropharmacology

Mathilde Boussac
Estelle Harroch
Karel Joineau
Emeline Descamps
Christine Brefel-Courbon

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1705937

2,214 views

Clinical Trial

Published on 07 Nov 2025

Evaluation of the pharmacokinetics, pharmacodynamics, and liver ultrasound imaging characteristics of a novel perfluoropropane microbubble in Chinese volunteers

in Drug Metabolism and Transport

Pengfei Li
Ping Du
Zhixia Zhao
Fei Jia
Weiyue Yu
Peng Qu
Jiangfan Li
Xuhong Wang
Lihong Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1704972

259 views

Mini Review

Published on 07 Nov 2025

Drug–herb interactions: a challenge and clinical concern in primary healthcare

in Family Medicine and Primary Care

Sujithra M.
Rammanohar Puthiyedath
Zeena S. Pillai

Frontiers in Medicine

doi 10.3389/fmed.2025.1657005

473 views

Original Research

Published on 07 Nov 2025

Postoperative outcomes in patients with COPD undergoing elective non-cardiac surgery: a propensity score-matched cohort study

in Intensive Care Medicine and Anesthesiology

Levan B. Berikashvili
Mariya M. Shemetova
Mikhail Ya Yadgarov
Kristina K. Kadantseva
Petr A. Polyakov
Alexey A. Yakovlev
Andrey G. Yavorovskiy
Valery V. Likhvantsev

Frontiers in Medicine

doi 10.3389/fmed.2025.1641613

480 views

Original Research

Published on 07 Nov 2025

Investigating the role of Akkermansia muciniphila Akk11 in modulating obesity and intestinal dysbiosis: a comparative study of live and pasteurized treatments

in Food Microbiology

Songhui Feng
Weitao Wang
Xin Zhang
Shimaa Elsayed Helal
Nan Peng
Zhenting Zhang

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1638771

961 views

Articles

DNA methylation and immune regulation in osteoporosis: emerging epigenetic targets for drug discovery

Impact of biologic therapy on blood cell indices and exacerbation risk in severe asthma: predictive value of the neutrophil-to-eosinophil ratio

Composite shoreline-retreat workflow (CoShReW): a case study on the Andalusian coast

Dysfunctions of sleep and the circadian rhythm in Huntington’s disease

Mindfulness training combined with cold water immersion effects on mood and perception of executive functioning in middle-aged and older adults: a pilot study

Impact of early vs. delayed intravenous magnesium sulfate on clinical outcomes in pediatric severe asthma: a retrospective cohort study

Biomechanical optimization study of posterior tilt extension stems in the repair of tibial plateau bone defects

The role of early human development and multidimensional enhancements in driving space adaptation and Universal Cognition

Correction: PFOA biomonitoring and kidney cancer risk: a meta-analysis of serum levels

STAT3 as a critical target of Sijunzi Decoction in the treatment of gastric cancer: evidence from integrated network pharmacology and experimental validation

Joint association of indoor allergens, endotoxins, heavy metals, and parabens with allergy-related outcomes in U. S. adults

Neuro-functional correlates of personality dimensions in Parkinson’s disease

Evaluation of the pharmacokinetics, pharmacodynamics, and liver ultrasound imaging characteristics of a novel perfluoropropane microbubble in Chinese volunteers

Drug–herb interactions: a challenge and clinical concern in primary healthcare

Postoperative outcomes in patients with COPD undergoing elective non-cardiac surgery: a propensity score-matched cohort study

Investigating the role of Akkermansia muciniphila Akk11 in modulating obesity and intestinal dysbiosis: a comparative study of live and pasteurized treatments