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5 articles related to "Allosteric Drugs"

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Articles

Original Research

Published on 11 Jul 2022

PASSer2.0: Accurate Prediction of Protein Allosteric Sites Through Automated Machine Learning

in Molecular Recognition

Sian Xiao
Hao Tian
Peng Tao

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.879251

11,815 views
56 citations

Mini Review

Published on 16 Dec 2014

Allosteric modulation of Ras and the PI3K/AKT/mTOR pathway: emerging therapeutic opportunities

in Gastrointestinal Sciences

Paul A. Hubbard
Colleen L. Moody
Ramachandran Murali

Frontiers in Physiology

doi 10.3389/fphys.2014.00478

14,611 views
47 citations

Review

Published on 09 Jan 2023

Modulating brain integrative actions as a new perspective on pharmacological approaches to neuropsychiatric diseases

in Molecular and Structural Endocrinology

Manuela Marcoli
Luigi F. Agnati
Rafael Franco
Pietro Cortelli
Deanna Anderlini
Diego Guidolin
Chiara Cervetto
Guido Maura

Frontiers in Endocrinology

doi 10.3389/fendo.2022.1038874

3,138 views
8 citations

Original Research

Published on 14 Oct 2022

Exploring the druggability of the binding site of aurovertin, an exogenous allosteric inhibitor of FOF1-ATP synthase

in Experimental Pharmacology and Drug Discovery

Luis Fernando Cofas-Vargas
Paola Mendoza-Espinosa
Luis Pablo Avila-Barrientos
Diego Prada-Gracia
Héctor Riveros-Rosas
Enrique García-Hernández

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1012008

7,439 views
8 citations

Original Research

Published on 18 Mar 2022

Mechanistic Insights Into Co-Administration of Allosteric and Orthosteric Drugs to Overcome Drug-Resistance in T315I BCR-ABL1

in Pharmacology of Anti-Cancer Drugs

Hao Zhang
Mingsheng Zhu
Mingzi Li
Duan Ni
Yuanhao Wang
Liping Deng
Kui Du
Shaoyong Lu
Hui Shi
Chen Cai

Frontiers in Pharmacology

doi 10.3389/fphar.2022.862504

5,702 views
25 citations