Binding Pockets | List of Frontiers open access articles

Original Research

Published on 03 Mar 2026

Long-term effects of rootstock and tree density on the economic profitability of ‘Delicious’ apple orchards in the Northeastern U.S

in Crop and Product Physiology

Luis Gonzalez Nieto
Stephen A. Hoying
Gemma Reig
Jaume Lordan
Poliana Francescatto
Michael J. Fargione
Gennaro Fazio
Terence L. Robinson

Frontiers in Plant Science

doi 10.3389/fpls.2026.1762635

Original Research

Published on 03 Mar 2026

Structural configuration and its controls on shale oil accumulation of the Wulalike formation at southern section of western margin, Ordos Basin

in Economic Geology

Jiayi Wei
Junfeng Ren
Xianghui Jing
Puyu Liu

Frontiers in Earth Science

doi 10.3389/feart.2026.1774568

236 views

Original Research

Published on 03 Mar 2026

Time-resolved transcriptomic analysis reveals key regulatory genes and auxin-responsive networks underlying axillary bud branching in Hippophae rhamnoides

in Plant Development and EvoDevo

Guozhen Yan
Qinggang Wei
Kaiwen Tan
Jin Lei
Junyang Wang
Cheng Tang
Feng Shi

Frontiers in Plant Science

doi 10.3389/fpls.2026.1746947

145 views

Original Research

Published on 03 Mar 2026

CD73 expression as a resistance mechanism in advanced EGFR-mutated non-small cell lung cancer

in Thoracic Oncology

Inger Johanne Zwicky Eide
Anne Pernille Harlem Dyrbekk
Ina Bisha
Thomas Haberichter
Sotirios Lakis
Jessica Chan
Arthur Lewis
Philip Martin
Zachary A. Cooper
Odd Terje Brustugun

Frontiers in Oncology

doi 10.3389/fonc.2026.1755595

139 views

Original Research

Published on 03 Mar 2026

Cognitive and emotional profiles in children with ASD, ADHD, and comorbid presentations: evidence for a distinct clinical phenotype

in Autism

Antonio Narzisi
Federica Barbetti
Maddalena Fabbri-Destro
Stefano Berloffa
Pamela Fantozzi
Valentina Viglione
Rosy Muccio
Elena Valente
Ilaria Accorinti
Elisa Foti

Frontiers in Psychiatry

doi 10.3389/fpsyt.2026.1765698

209 views

Original Research

Published on 03 Mar 2026

The role of hypothyroidism in the resilience against depressive episodes during covid pandemic in a cohort of old adults

in Mood Disorders

Alessandra Perra
Massimo Tusconi
Elisa Cantone
Michela Atzeni
Enzo Tramontano
Stefano Lorrai
Fabrizio Bert
Antonio E. Nardi
Mauro Giovanni Carta
Giulia Cossu

Frontiers in Psychiatry

doi 10.3389/fpsyt.2026.1603347

267 views

Correction

Published on 03 Mar 2026

Correction: MaxEnt model-based prediction of potential suitable habitats of three Trichosanthes L. species in China under future climate change scenarios

in Functional Plant Ecology

Xiaomeng Wang
Yuanyuan Ding
Chunfeng Duan
Yunchuan Xu
Chen Zhang
Zihan Wang

Frontiers in Plant Science

doi 10.3389/fpls.2026.1810021

Review

Published on 03 Mar 2026

Multiscale computational genomics in Wilson disease: from atomic dynamics to clinical prediction

in Computational Genomics

Moujun Luan
Qingkai Xue
Yujie Cao
Gangli Cheng
Xingxing Huo

Frontiers in Genetics

doi 10.3389/fgene.2026.1766223

116 views

Original Research

Published on 03 Mar 2026

A comprehensive evaluation of non-vascular prepontine cistern anatomy influencing trigeminal nerve vulnerability using machine learning-based morphometric analysis

in Precision Medicine

Akçay Övünç Karadaş
Gokalp Tulum
Ömer Karadaş
Muhammet İkbal Işık
Ferhat Cüce
Onur Osman
Zehra Şimşek
Necibe Sare Mert
Niray Baş
Berza Özcan

Frontiers in Medicine

doi 10.3389/fmed.2026.1745815

Case Report

Published on 03 Mar 2026

Targeted and immunotherapy based on tissue of origin in carcinoma of unknown primary: a two-case report and literature review

in Cancer Molecular Targets and Therapeutics

Mei Wang
DongYue Yan
Wen Sun
Jingshan Liang

Frontiers in Oncology

doi 10.3389/fonc.2026.1741467

120 views

Systematic Review

Published on 03 Mar 2026

Association between diabetes mellitus and risk of Alzheimer’s disease: a meta-analysis and systematic review

in Clinical Diabetes

Ju Wu
Jin Li
Xiaolan Qin
Weiping Chen

Frontiers in Endocrinology

doi 10.3389/fendo.2026.1736410

194 views

Review

Published on 03 Mar 2026

Spatiotemporal control of immunogenic cell death: rewiring tumor-immune dialogues for next-generation immunotherapy

in Cancer Immunity and Immunotherapy

Chengbin Li
Lu Zhu
Yubing Wang
Lei Zhao
Xing Lin
Zhixian Sun
Tingxi Yan
Yingduo Wang
Junjie Piao
Aihua Jin

Frontiers in Immunology

doi 10.3389/fimmu.2026.1784935

Systematic Review

Published on 03 Mar 2026

Hyperbaric oxygen therapy modulates immune effector responses and reshapes peripheral immune tolerance: a narrative review

in Immunological Tolerance and Regulation

Shuhao Mei
Boran Dong
Yuling Gao
Jiaqi Zhou
Hailian Yi
Yuyin Han
Wenzhen Zhuo
Mengyan Sun
Meiting Li
Han Wang

Frontiers in Immunology

doi 10.3389/fimmu.2026.1777972

114 views

Original Research

Published on 03 Mar 2026

The impact of ward noise management and comprehensive nursing intervention on cognitive function, psychological health, and prognosis of post-stroke patients: a randomized controlled trial

in Neurorehabilitation

Yuan Deng
Yanmin Liu
Jie Liu
Yufei Sang
Fang Wang

Frontiers in Neurology

doi 10.3389/fneur.2026.1778278

Original Research

Published on 03 Mar 2026

Outcomes in heart failure patients with third-degree heart block during COVID-19

in Cardiac Rhythmology

Benjamin Kash
Ethan Wahle
Eli Blaney
Saif Zurob
Amjad Kabach
Ali Bin Abdul Jabbar

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2026.1701620

Systematic Review

Published on 03 Mar 2026

How circular is your product? A systematic literature review on the circular product development process

in Circular Economy

Paulo Henrique Paulista
Carlos Henrique Pereira Mello
Jeniffer de Nadae
Patricia Kelli da Silva Oliveira

Frontiers in Sustainability

doi 10.3389/frsus.2025.1721603

589 views

Articles

Long-term effects of rootstock and tree density on the economic profitability of ‘Delicious’ apple orchards in the Northeastern U.S

Structural configuration and its controls on shale oil accumulation of the Wulalike formation at southern section of western margin, Ordos Basin

Time-resolved transcriptomic analysis reveals key regulatory genes and auxin-responsive networks underlying axillary bud branching in Hippophae rhamnoides

CD73 expression as a resistance mechanism in advanced EGFR-mutated non-small cell lung cancer

Cognitive and emotional profiles in children with ASD, ADHD, and comorbid presentations: evidence for a distinct clinical phenotype

The role of hypothyroidism in the resilience against depressive episodes during covid pandemic in a cohort of old adults

Correction: MaxEnt model-based prediction of potential suitable habitats of three Trichosanthes L. species in China under future climate change scenarios

Multiscale computational genomics in Wilson disease: from atomic dynamics to clinical prediction

A comprehensive evaluation of non-vascular prepontine cistern anatomy influencing trigeminal nerve vulnerability using machine learning-based morphometric analysis

Targeted and immunotherapy based on tissue of origin in carcinoma of unknown primary: a two-case report and literature review

Association between diabetes mellitus and risk of Alzheimer’s disease: a meta-analysis and systematic review

Spatiotemporal control of immunogenic cell death: rewiring tumor-immune dialogues for next-generation immunotherapy

Hyperbaric oxygen therapy modulates immune effector responses and reshapes peripheral immune tolerance: a narrative review

The impact of ward noise management and comprehensive nursing intervention on cognitive function, psychological health, and prognosis of post-stroke patients: a randomized controlled trial

Outcomes in heart failure patients with third-degree heart block during COVID-19

How circular is your product? A systematic literature review on the circular product development process