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4 articles related to "Bioisostere"

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Articles

Original Research

Published on 17 Nov 2022

Discovery of (R)-2-amino-3-triazolpropanoic acid derivatives as NMDA receptor glycine site agonists with GluN2 subunit-specific activity

in Medicinal and Pharmaceutical Chemistry

Fabao Zhao
Georgios Mazis
Feng Yi
James S. Lotti
Michael S. Layeux
Eric P. Schultz
Lennart Bunch
Kasper B. Hansen
Rasmus P. Clausen

Frontiers in Chemistry

doi 10.3389/fchem.2022.1008233

5,877 views
6 citations

Review

Published on 04 Mar 2019

Recent Advances for the Direct Introduction of the CF2Me Moiety

in Organic Chemistry

Elodie Carbonnel
Thomas Poisson
Philippe Jubault
Xavier Pannecoucke
Tatiana Besset

Frontiers in Chemistry

doi 10.3389/fchem.2019.00111

9,540 views
20 citations

Original Research

Published on 16 Aug 2021

Development of an Antibiotic Resistance Breaker to Resensitize Drug-Resistant Staphylococcus aureus: In Silico and In Vitro Approach

in Clinical and Diagnostic Microbiology and Immunology

Gopalakrishnan Thamilselvan
Hema Bhagavathi Sarveswari
Sahana Vasudevan
Alex Stanley
Karthi Shanmugam
Pothiappan Vairaprakash
Adline Princy Solomon

Frontiers in Cellular and Infection Microbiology

doi 10.3389/fcimb.2021.700198

7,188 views
10 citations

Original Research

Published on 09 Aug 2023

Derivatives of 9-phosphorylated acridine as butyrylcholinesterase inhibitors with antioxidant activity and the ability to inhibit β-amyloid self-aggregation: potential therapeutic agents for Alzheimer’s disease

in Experimental Pharmacology and Drug Discovery

Galina F. Makhaeva
Nadezhda V. Kovaleva
Elena V. Rudakova
Natalia P. Boltneva
Sofya V. Lushchekina
Tatiana Yu Astakhova
Elena N. Timokhina
Olga G. Serebryakova
Alexander V. Shchepochkin
Maxim A. Averkov

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1219980

5,469 views
9 citations