Brain Slice Culture | List of Frontiers open access articles

Original Research

Published on 22 May 2025

Investigating the use of cuprizone and lysolecithin to model demyelination ex vivo in sagittal rat brain organotypic slice cultures

in Non-Neuronal Cells

Brooke Hawker
Bronwen Connor
Amy McCaughey-Chapman

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2025.1609806

3,328 views

Original Research

Published on 21 Dec 2020

Organotypic Brain Slice Culture Microglia Exhibit Molecular Similarity to Acutely-Isolated Adult Microglia and Provide a Platform to Study Neuroinflammation

in Non-Neuronal Cells

Alex R. D. Delbridge
Dann Huh
Margot Brickelmaier
Jeremy C. Burns
Chris Roberts
Ravi Challa
Naideline Raymond
Patrick Cullen
Thomas M. Carlile
Katelin A. Ennis

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2020.592005

29,235 views
56 citations

Original Research

Published on 26 Jun 2024

Modeling demyelination and endogenous remyelination in spinal cord ex vivo rat organotypic slice cultures

in Non-Neuronal Cells

Brooke Hawker
Muna Dhakal
Bronwen Connor
Amy McCaughey-Chapman

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2024.1345042

3,862 views
3 citations

Original Research

Published on 05 Feb 2019

Combination Therapy With Fingolimod and Neural Stem Cells Promotes Functional Myelination in vivo Through a Non-immunomodulatory Mechanism

in Cellular Neurophysiology

Yuan Zhang
Xin-Yu Lu
Ze-Qin Ye
Bogoljub Ciric
Cun-Gen Ma
Abdolmohamad Rostami
Xing Li
Guang-Xian Zhang

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2019.00014

4,246 views
8 citations

Original Research

Published on 16 Feb 2022

Exposure of α-Synuclein Aggregates to Organotypic Slice Cultures Recapitulates Key Molecular Features of Parkinson's Disease

in Movement Disorders

Serge Moudio
Fredrik Rodin
Nazira Jamal Albargothy
Urban Karlsson
Juan F. Reyes
Martin Hallbeck

Frontiers in Neurology

doi 10.3389/fneur.2022.826102

6,565 views
7 citations

Original Research

Published on 02 Oct 2018

Conventional Anti-glioblastoma Chemotherapy Affects Proteoglycan Composition of Brain Extracellular Matrix in Rat Experimental Model in vivo

in Cancer Molecular Targets and Therapeutics

Alexandra Y. Tsidulko
Cynthia Bezier
Gabin de La Bourdonnaye
Anastasia V. Suhovskih
Tatiana M. Pankova
Galina M. Kazanskaya
Svetlana V. Aidagulova
Elvira V. Grigorieva

Frontiers in Pharmacology

doi 10.3389/fphar.2018.01104

5,277 views
25 citations

Original Research

Published on 27 Jan 2026

Adult organotypic brain slice cultures recapitulate extracellular matrix remodeling in hemorrhagic stroke

in Cellular Neuropathology

Benjamin J. Hewitt
Lauren Roberts
James A. Roberts
Daniel Fulton
Lisa J. Hill
Philip Kitchen
Roslyn M. Bill
Hannah F. Botfield

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2025.1722240

1,113 views

Original Research

Published on 06 Apr 2023

Unraveling astrocyte behavior in the space brain: Radiation response of primary astrocytes

in Radiation and Health

Marie Denise Roggan
Jessica Kronenberg
Esther Wollert
Sven Hoffmann
Hasan Nisar
Bikash Konda
Sebastian Diegeler
Christian Liemersdorf
Christine E. Hellweg

Frontiers in Public Health

doi 10.3389/fpubh.2023.1063250

8,386 views
13 citations

Articles

Investigating the use of cuprizone and lysolecithin to model demyelination ex vivo in sagittal rat brain organotypic slice cultures

Organotypic Brain Slice Culture Microglia Exhibit Molecular Similarity to Acutely-Isolated Adult Microglia and Provide a Platform to Study Neuroinflammation

Modeling demyelination and endogenous remyelination in spinal cord ex vivo rat organotypic slice cultures

Combination Therapy With Fingolimod and Neural Stem Cells Promotes Functional Myelination in vivo Through a Non-immunomodulatory Mechanism

Exposure of α-Synuclein Aggregates to Organotypic Slice Cultures Recapitulates Key Molecular Features of Parkinson's Disease

Conventional Anti-glioblastoma Chemotherapy Affects Proteoglycan Composition of Brain Extracellular Matrix in Rat Experimental Model in vivo

Adult organotypic brain slice cultures recapitulate extracellular matrix remodeling in hemorrhagic stroke

Unraveling astrocyte behavior in the space brain: Radiation response of primary astrocytes