Bsab | List of Frontiers open access articles

Original Research

Published on 03 Sep 2025

Physicochemical and biological characterization of a bispecific antibody in a CrossMab/KIH format that targets EGFR and VEGF-A

in Cancer Immunity and Immunotherapy

Safiat Ayinde
Shraboni Dutta
Nishant Mohan
Wen Jin Wu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1659966

3,939 views

Original Research

Published on 23 Feb 2022

IgG-like Bispecific Antibody CD3×EpCAM Generated by Split Intein Against Colorectal Cancer

in Drug Metabolism and Transport

Lei Wang
Yu Qiao
Huifang Zong
Lei Han
Yong Ke
ZhiDi Pan
Jie Chen
Jun Lu
Jinyao Li
Tianlei Ying

Frontiers in Pharmacology

doi 10.3389/fphar.2022.803059

8,678 views
11 citations

Perspective

Published on 30 Jul 2025

A roadmap to implementing outpatient administration of bispecific antibodies in multiple myeloma

in Hematologic Malignancies

Alfred L. Garfall
Rahul Banerjee
Laurent Frenzel
Cyrus Khandanpour
Yi Lin
Erica Ottoni
Robert Rifkin
Sarah Rockwell
Cesar Rodriguez
Humberto Villefort

Frontiers in Oncology

doi 10.3389/fonc.2025.1630146

9,607 views
3 citations

Original Research

Published on 27 Feb 2026

Generation and preclinical characterization of a novel bispecific CD19-TCRgammadelta antibody for the treatment of B cell acute lymphoblastic leukemia

in Cancer Immunity and Immunotherapy

Joseph Kauer
Fabian Vogt
Sebastian Hörner
Valentin Schmidt
Carsten Müller-Tidow
Simon Raffel
Helmut R. Salih
Gundram Jung
Martin Pflügler

Frontiers in Immunology

doi 10.3389/fimmu.2026.1728424

540 views

Review

Published on 10 Nov 2021

Dual Targeting of Multiple Myeloma Stem Cells and Myeloid-Derived Suppressor Cells for Treatment of Chemotherapy-Resistant Multiple Myeloma

in Hematologic Malignancies

Fatih M. Uckun

Frontiers in Oncology

doi 10.3389/fonc.2021.760382

7,117 views
14 citations

Review

Published on 07 May 2020

Bispecific, T-Cell-Recruiting Antibodies in B-Cell Malignancies

in Cancer Immunity and Immunotherapy

Margaux Lejeune
Murat Cem Köse
Elodie Duray
Hermann Einsele
Yves Beguin
Jo Caers

Frontiers in Immunology

doi 10.3389/fimmu.2020.00762

33,903 views
84 citations

Original Research

Published on 26 Sep 2023

A novel bispecific antibody dual-targeting approach for enhanced neutralization against fast-evolving SARS-CoV-2 variants

in Vaccines and Molecular Therapeutics

Ji Woong Kim
Hyun Jung Kim
Kyun Heo
Yoonwoo Lee
Hui Jeong Jang
Ho-Young Lee
Jun Won Park
Yea Bin Cho
Ji Hyun Lee
Ha Gyeong Shin

Frontiers in Immunology

doi 10.3389/fimmu.2023.1271508

6,314 views
15 citations

Review

Published on 01 Dec 2023

Revolutionizing cancer immunotherapy: unleashing the potential of bispecific antibodies for targeted treatment

in Cancer Immunity and Immunotherapy

Xiaohan Guo
Yi Wu
Ying Xue
Na Xie
Guobo Shen

Frontiers in Immunology

doi 10.3389/fimmu.2023.1291836

14,963 views
22 citations

Original Research

Published on 19 Feb 2021

Novel Bispecific Antibody for Synovial-Specific Target Delivery of Anti-TNF Therapy in Rheumatoid Arthritis

in Autoimmune and Autoinflammatory Disorders

Mathieu Ferrari
Shimobi C. Onuoha
Liliane Fossati-Jimack
Alessandra Nerviani
Pedro L. Alves
Sara Pagani
Cecilia Deantonio
Federico Colombo
Claudio Santoro
Daniele Sblattero

Frontiers in Immunology

doi 10.3389/fimmu.2021.640070

10,003 views
15 citations

Original Research

Published on 05 Aug 2022

CRISPR screening identifies T cell-intrinsic regulators of CD3-bispecific antibody responses

in Cancer Immunity and Immunotherapy

Ryan D. Molony
Theresa Funk
Gina Trabucco
Erik Corcoran
David Ruddy
Malini Varadarajan
GiNell Elliot
Michelle Piquet
Joni Lam
Matthew J. Meyer

Frontiers in Immunology

doi 10.3389/fimmu.2022.909979

10,252 views
5 citations

Systematic Review

Published on 29 Sep 2025

CAR T-cells vs. bispecific antibodies as third- or later-line treatment for relapsed/refractory follicular lymphoma: a literature review and meta-analysis

in Cancer Immunity and Immunotherapy

Ying He
Ling Qiu
Dan Chen
Shi-hui Ren
Ya-xin Xiong
Meng-jiao Li
Bai-tao Dou
Yan-ling Li
Ya-li Cen
Yun-ming Li

Frontiers in Immunology

doi 10.3389/fimmu.2025.1611984

6,320 views
1 citation

Original Research

Published on 28 Nov 2022

PD-1/LAG-3 bispecific antibody potentiates T cell activation and increases antitumor efficacy

in Cancer Immunity and Immunotherapy

Ning Shi
Yangyihua Zhou
Yujun Liu
Ran Zhang
Xingjun Jiang
Caiping Ren
Xiang Gao
Longlong Luo

Frontiers in Immunology

doi 10.3389/fimmu.2022.1047610

13,822 views
28 citations

Original Research

Published on 11 Jun 2024

PHE1-based IgG-like antibody platform provides a novel strategy for enhanced T-cell immunotherapy

in Vaccines and Molecular Therapeutics

Lingbin Wang
Haojie Jiang
Xuying Yin
Tingting Liang
Guoming Li
Chen Ding
Mina Yang
Lin Zhang
Junling Liu
Yanyan Xu

Frontiers in Immunology

doi 10.3389/fimmu.2024.1415834

4,188 views

Perspective

Published on 10 Feb 2025

Six events that shaped antibody approvals in oncology

in Cancer Immunity and Immunotherapy

Suman Paul
Shibin Zhou

Frontiers in Immunology

doi 10.3389/fimmu.2025.1533796

8,709 views
6 citations

Mini Review

Published on 10 Feb 2025

Improving CD3 bispecific antibody therapy in solid tumors using combination strategies

in Cancer Molecular Targets and Therapeutics

Katy Lloyd
Jim Middelburg
Vitalijs Ovcinnikovs
Nora Pencheva
Kristel Kemper
Thorbald van Hall

Frontiers in Oncology

doi 10.3389/fonc.2025.1548446

7,889 views
3 citations

Review

Published on 10 Oct 2024

Bispecific antibody targets and therapies in multiple myeloma

in Cancer Immunity and Immunotherapy

Matthew Rees
Nadine Abdallah
Binoy Yohannan
Wilson I. Gonsalves

Frontiers in Immunology

doi 10.3389/fimmu.2024.1424925

12,591 views
7 citations

Articles

Physicochemical and biological characterization of a bispecific antibody in a CrossMab/KIH format that targets EGFR and VEGF-A

IgG-like Bispecific Antibody CD3×EpCAM Generated by Split Intein Against Colorectal Cancer

A roadmap to implementing outpatient administration of bispecific antibodies in multiple myeloma

Generation and preclinical characterization of a novel bispecific CD19-TCRgammadelta antibody for the treatment of B cell acute lymphoblastic leukemia

Dual Targeting of Multiple Myeloma Stem Cells and Myeloid-Derived Suppressor Cells for Treatment of Chemotherapy-Resistant Multiple Myeloma

Bispecific, T-Cell-Recruiting Antibodies in B-Cell Malignancies

A novel bispecific antibody dual-targeting approach for enhanced neutralization against fast-evolving SARS-CoV-2 variants

Revolutionizing cancer immunotherapy: unleashing the potential of bispecific antibodies for targeted treatment

Novel Bispecific Antibody for Synovial-Specific Target Delivery of Anti-TNF Therapy in Rheumatoid Arthritis

CRISPR screening identifies T cell-intrinsic regulators of CD3-bispecific antibody responses

CAR T-cells vs. bispecific antibodies as third- or later-line treatment for relapsed/refractory follicular lymphoma: a literature review and meta-analysis

PD-1/LAG-3 bispecific antibody potentiates T cell activation and increases antitumor efficacy

PHE1-based IgG-like antibody platform provides a novel strategy for enhanced T-cell immunotherapy

Six events that shaped antibody approvals in oncology

Improving CD3 bispecific antibody therapy in solid tumors using combination strategies

Bispecific antibody targets and therapies in multiple myeloma