Clinical Transformation | List of Frontiers open access articles

Review

Published on 24 Nov 2025

PARP inhibitors as radiosensitizers: a comprehensive review of preclinical evidence and clinical applications

in Pharmacology of Anti-Cancer Drugs

Xiaodong Luo
Shuo Gao
Kaiyang Sun
Zhiqiang Dong
Shude Yang

Frontiers in Oncology

doi 10.3389/fonc.2025.1702121

2,067 views

Original Research

Published on 19 Sep 2024

The application and clinical translation of the self-evolving machine learning methods in predicting diabetic retinopathy and visualizing clinical transformation

in Clinical Diabetes

Binbin Li
Liqun Hu
Siqing Zhang
Shaojun Li
Wei Tang
Guishang Chen

Frontiers in Endocrinology

doi 10.3389/fendo.2024.1429974

2,157 views
3 citations

Review

Published on 24 Feb 2026

CRISPR-based diagnostics for infectious diseases: mechanisms, advancements and clinical transformation prospects

in Clinical and Diagnostic Microbiology and Immunology

Zhenzhen Pan
Ling Xu
Zihao Fan
Yaling Cao
Feng Ren

Frontiers in Cellular and Infection Microbiology

doi 10.3389/fcimb.2026.1769226

321 views

Systematic Review

Published on 10 Mar 2022

Therapeutic Effect of Exosomes Derived From Stem Cells in Spinal Cord Injury: A Systematic Review Based on Animal Studies

in Experimental Therapeutics

Cangyu Zhang
Rongrong Deng
Guangzhi Zhang
Xuegang He
Haiwei Chen
Bao Chen
Lin Wan
Xuewen Kang

Frontiers in Neurology

doi 10.3389/fneur.2022.847444

6,887 views
24 citations

Original Research

Published on 28 Sep 2022

Self-assembled peptide-paclitaxel nanoparticles for enhancing therapeutic efficacy in colorectal cancer

in Biomaterials

Lidan Hou
Ting Zhong
Peng Cheng
Bohan Long
Leilei Shi
Xiangjun Meng
Han Yao

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2022.938662

4,633 views
18 citations

Review

Published on 15 Jan 2026

From ketogenic metabolism to targeted therapeutics: current advances in β-hydroxybutyrylation

in Cancer Immunity and Immunotherapy

Fangshuai Hu
Changming Liang
Xu Zhang
Lishuai Xu
Chengwei Wu
Senlin Wan
Jiawei Wang
Mengyun Wang
Dawei Zhang
Yongchun Liu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1690224

1,349 views

Original Research

Published on 03 Apr 2025

Effectiveness of Perfusion Index ratio and End-Diastolic Velocity ratio in evaluating the efficacy of Interscalene Brachial Plexus Block: a prospective observational study

in Intensive Care Medicine and Anesthesiology

Li Hu
Jintao Sun
Bin Zhang
Xiaoyan Ye
Jian Lu
Zhipeng Zhu
Hongmei Zhou

Frontiers in Medicine

doi 10.3389/fmed.2025.1571171

1,851 views

Review

Published on 12 Oct 2022

Bacterial DNA involvement in carcinogenesis

in Adaptive & Innate Immunity in Infection

Wang Yangyanqiu
Han Shuwen

Frontiers in Cellular and Infection Microbiology

doi 10.3389/fcimb.2022.996778

12,108 views
17 citations

Review

Published on 19 May 2023

Critical roles of m6A methylation in cardiovascular diseases

in Cardiovascular Genetics and Systems Medicine

Xinmin Zhang
He Cai
He Xu
Su Dong
Haichun Ma

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2023.1187514

5,156 views
15 citations

Review

Published on 29 Jun 2023

Role of exosomes in the development of the immune microenvironment in hepatocellular carcinoma

in Cancer Immunity and Immunotherapy

Tanghua Li
Jiapeng Jiao
Haoteng Ke
Wenshan Ouyang
Luobin Wang
Jin Pan
Xin Li

Frontiers in Immunology

doi 10.3389/fimmu.2023.1200201

6,805 views
20 citations

Review

Published on 04 Apr 2022

Celastrol: An Update on Its Hepatoprotective Properties and the Linked Molecular Mechanisms

in Gastrointestinal and Hepatic Pharmacology

Mengzhen Li
Faren Xie
Lu Wang
Guoxue Zhu
Lian-Wen Qi
Shujun Jiang

Frontiers in Pharmacology

doi 10.3389/fphar.2022.857956

7,339 views
21 citations

Review

Published on 03 Aug 2023

Bacteria-based immunotherapy for cancer: a systematic review of preclinical studies

in Microbial Immunology

Min Zhou
Yucheng Tang
Wenjie Xu
Xinyan Hao
Yongjiang Li
Si Huang
Daxiong Xiang
Junyong Wu

Frontiers in Immunology

doi 10.3389/fimmu.2023.1140463

21,371 views
56 citations

Review

Published on 10 Sep 2021

A Novel Treatment for Ewing’s Sarcoma: Chimeric Antigen Receptor-T Cell Therapy

in T Cell Biology

Zili Lin
Ziyi Wu
Wei Luo

Frontiers in Immunology

doi 10.3389/fimmu.2021.707211

15,726 views
22 citations

Review

Published on 02 Nov 2021

Gut Microbiome-Mediated Alteration of Immunity, Inflammation, and Metabolism Involved in the Regulation of Non-alcoholic Fatty Liver Disease

in Microbial Immunology

Li-Hong He
Dun-Han Yao
Ling-Yun Wang
Lei Zhang
Xue-Li Bai

Frontiers in Microbiology

doi 10.3389/fmicb.2021.761836

9,377 views
45 citations

Review

Accepted on 16 Feb 2026

Neutrophil Extracellular Traps in Pulmonary Fibrosis: Mechanisms, Immunity and Therapeutic Targets

in Inflammation

Jing Wu
Yongbin Hu

Frontiers in Immunology

Review

Published on 04 Apr 2022

Bacteria−Based Synergistic Therapy in the Backdrop of Synthetic Biology

in Cancer Immunity and Immunotherapy

Yawei Bao
Yong Cheng
Wei Liu
Wenguang Luo
Peijie Zhou
Dong Qian

Frontiers in Oncology

doi 10.3389/fonc.2022.845346

4,514 views
10 citations

Articles

PARP inhibitors as radiosensitizers: a comprehensive review of preclinical evidence and clinical applications

The application and clinical translation of the self-evolving machine learning methods in predicting diabetic retinopathy and visualizing clinical transformation

CRISPR-based diagnostics for infectious diseases: mechanisms, advancements and clinical transformation prospects

Therapeutic Effect of Exosomes Derived From Stem Cells in Spinal Cord Injury: A Systematic Review Based on Animal Studies

Self-assembled peptide-paclitaxel nanoparticles for enhancing therapeutic efficacy in colorectal cancer

From ketogenic metabolism to targeted therapeutics: current advances in β-hydroxybutyrylation

Effectiveness of Perfusion Index ratio and End-Diastolic Velocity ratio in evaluating the efficacy of Interscalene Brachial Plexus Block: a prospective observational study

Bacterial DNA involvement in carcinogenesis

Critical roles of m6A methylation in cardiovascular diseases

Role of exosomes in the development of the immune microenvironment in hepatocellular carcinoma

Celastrol: An Update on Its Hepatoprotective Properties and the Linked Molecular Mechanisms

Bacteria-based immunotherapy for cancer: a systematic review of preclinical studies

A Novel Treatment for Ewing’s Sarcoma: Chimeric Antigen Receptor-T Cell Therapy

Gut Microbiome-Mediated Alteration of Immunity, Inflammation, and Metabolism Involved in the Regulation of Non-alcoholic Fatty Liver Disease

Neutrophil Extracellular Traps in Pulmonary Fibrosis: Mechanisms, Immunity and Therapeutic Targets

Bacteria−Based Synergistic Therapy in the Backdrop of Synthetic Biology