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3 articles related to "Cocktail Approach"

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Articles

Original Research

Published on 14 Feb 2020

Limited Sampling Modeling for Estimation of Phenotypic Metrics for CYP Enzymes and the ABCB1 Transporter Using a Cocktail Approach

in Drug Metabolism and Transport

Eduardo Barbosa Coelho
Diego Alberto Ciscato Cusinato
João Paulo Ximenez
Vera Lucia Lanchote
Claudio José Struchiner
Guilherme Suarez-Kurtz

Frontiers in Pharmacology

doi 10.3389/fphar.2020.00022

3,473 views
10 citations

Original Research

Published on 17 Sep 2021

Quantification of CYP3A and Drug Transporters Activity in Healthy Young, Healthy Elderly and Chronic Kidney Disease Elderly Patients by a Microdose Cocktail Approach

in Drug Metabolism and Transport

Punyabhorn Rattanacheeworn
Stephen J Kerr
Wonngarm Kittanamongkolchai
Natavudh Townamchai
Suwasin Udomkarnjananun
Kearkiat Praditpornsilpa
Thanundorn Thanusuwannasak
Udomsak Udomnilobol
Suree Jianmongkol
Boonsri Ongpipattanakul

Frontiers in Pharmacology

doi 10.3389/fphar.2021.726669

7,024 views
23 citations

Original Research

Published on 02 Feb 2024

Measurement of CYP1A2 and CYP3A4 activity by a simplified Geneva cocktail approach in a cohort of free-living individuals: a pilot study

in Pharmacogenetics and Pharmacogenomics

Constance A. Sobsey
Noor Mady
Vincent R. Richard
Andre LeBlanc
Thomas Zakharov
Christoph H. Borchers
R. Thomas Jagoe

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1232595

4,185 views
3 citations