Crm197 | List of Frontiers open access articles

Original Research

Published on 12 Aug 2025

Enhancement of immunogenicity of SARS-CoV-2 spike protein expressed in Escherichia coli by fusion of the CRM197 functional domain

in Virology

Xibing Yu
Yinmeng Yang
Miao Zhang
Qiantong Shen
Yun Zhu
Tong An
Siqi Li
Kexin Zhang
Shuaiyao Lu
Shaohong Lu

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1650239

1,996 views

Original Research

Published on 17 Aug 2022

Layered and integrated medical countermeasures against Burkholderia pseudomallei infections in C57BL/6 mice

in Infectious Agents and Disease

Christopher P. Klimko
Jennifer L. Shoe
Nathaniel O. Rill
Melissa Hunter
Jennifer L. Dankmeyer
Yuli Talyansky
Lindsey K. Schmidt
Caitlyn E. Orne
David P. Fetterer
Sergei S. Biryukov

Frontiers in Microbiology

doi 10.3389/fmicb.2022.965572

4,750 views
13 citations

Original Research

Published on 05 Jul 2021

A Porphyromonas gingivalis Capsule-Conjugate Vaccine Protects From Experimental Oral Bone Loss

in Oral Infections and Microbes

Fernanda G. Rocha
Aym Berges
Angie Sedra
Shirin Ghods
Neeraj Kapoor
Lucy Pill
Mary Ellen Davey
Jeff Fairman
Frank C. Gibson

Frontiers in Oral Health

doi 10.3389/froh.2021.686402

10,070 views
10 citations

Original Research

Published on 21 Mar 2022

Development of Klebsiella pneumoniae Capsule Polysaccharide-Conjugated Vaccine Candidates Using Phage Depolymerases

in Vaccines and Molecular Therapeutics

Tzu-Lung Lin
Feng-Ling Yang
Chien-Tai Ren
Yi-Jiun Pan
Kuo-Shiang Liao
I-Fan Tu
Yu-Pei Chang
Yang-Yu Cheng
Chung-Yi Wu
Shih-Hsiung Wu

Frontiers in Immunology

doi 10.3389/fimmu.2022.843183

15,686 views
57 citations

Methods

Published on 27 Nov 2012

Development of novel O-polysaccharide based glycoconjugates for immunization against glanders

in Clinical and Diagnostic Microbiology and Immunology

Mary N Burtnick
Christian Heiss
A. Michele Schuler
Parastoo Azadi
Paul J Brett

Frontiers in Cellular and Infection Microbiology

doi 10.3389/fcimb.2012.00148

6,238 views
24 citations

Original Research

Published on 16 Oct 2023

Post-marketing safety surveillance for both CRM197 and TT carrier proteins PCV13 in Jiangsu, China

in Infectious Diseases: Epidemiology and Prevention

Ran Hu
Yuanbao Liu
Lei Zhang
Guodong Kang
Borong Xu
Mingma Li
Jing Yu
Yuanyuan Zhu
Hongxiong Guo
Zhiguo Wang

Frontiers in Public Health

doi 10.3389/fpubh.2023.1272562

2,933 views
6 citations

Clinical Trial

Published on 05 Nov 2021

A Novel Combined Conjugate Therapeutic Cancer Vaccine, Recombinant EGF-CRM197, in Patients With Advanced Solid Tumors: A Phase I Clinical Study

in Cancer Immunity and Immunotherapy

An-Wen Xiong
Jue-Min Fang
Sheng-Xiang Ren
Wei Li
Jing Wang
Yu Zhao
Guo-You Chen
Qing Xu
Cai-Cun Zhou

Frontiers in Oncology

doi 10.3389/fonc.2021.745699

5,411 views
11 citations

Articles

Enhancement of immunogenicity of SARS-CoV-2 spike protein expressed in Escherichia coli by fusion of the CRM197 functional domain

Layered and integrated medical countermeasures against Burkholderia pseudomallei infections in C57BL/6 mice

A Porphyromonas gingivalis Capsule-Conjugate Vaccine Protects From Experimental Oral Bone Loss

Development of Klebsiella pneumoniae Capsule Polysaccharide-Conjugated Vaccine Candidates Using Phage Depolymerases

Development of novel O-polysaccharide based glycoconjugates for immunization against glanders

Post-marketing safety surveillance for both CRM197 and TT carrier proteins PCV13 in Jiangsu, China

A Novel Combined Conjugate Therapeutic Cancer Vaccine, Recombinant EGF-CRM197, in Patients With Advanced Solid Tumors: A Phase I Clinical Study