Deep Space | List of Frontiers open access articles

Case Report

Published on 27 Aug 2025

Recurrent rectal cancer cured by transsacral prone longitudinal incision combined with bilateral gluteus maximus “kite” flap filling: a case report

in Surgical Oncology

Lixia Zhang
Xiaoling Jiang
Maoyuan Wu
Wenwen Zhang
Guanyan Wang
Wei Yang
Tingchao Li
Lianli He
Gangcheng Wang

Frontiers in Oncology

doi 10.3389/fonc.2025.1550960

286 views

Original Research

Published on 27 Aug 2025

A faked prolongation of an endurance target time does not affect muscle fatigue but increases perceived exertion

in Movement Science

Max Herzberg
Jenny Rosendahl
Lena Mader
Christoph Anders

Frontiers in Psychology

doi 10.3389/fpsyg.2025.1466750

267 views

Original Research

Published on 27 Aug 2025

Corneal stromal microdots accumulation and its association with corneal neurodegeneration and retinal microvascular perfusion in diabetes

in Clinical Diabetes

Jingrao Wang
Shu Wang
Hong Zhang
Xin Jin

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1481018

306 views

Original Research

Published on 27 Aug 2025

CEACAM6 as a machine learning derived immune biomarker for predicting neoadjuvant chemotherapy response in HR+/HER2− breast cancer

in Systems Immunology

Dalang Fang
Jie Lin
Jin Wang
Qingxiao Nong
Shouwen Tao
Bimin Lu
Yanrong Yu
Hao Peng
Yingying Tian
Qunying Su

Frontiers in Immunology

doi 10.3389/fimmu.2025.1662004

441 views

Original Research

Published on 27 Aug 2025

Association of neonatal hypothermia with neonatal hypoglycemia

in Pediatric Endocrinology

Henrike Hoermann
Marcia Roeper
Lisa Friesl
Calvin Kurz
Juliane Tautz
Mark Dzietko
Ertan Mayatepek
Thomas Meissner
Sebastian Kummer

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1641140

765 views

Original Research

Published on 27 Aug 2025

A genetically determined molecular switch modulates the anti-inflammatory potential of human IgA

in Inflammation

Andrew W. Gibson
Jianming Wu
R. Curtis Hendrickson
Travis Ptacek
James Mobley
Jeffrey C. Edberg
Robert P. Kimberly

Frontiers in Immunology

doi 10.3389/fimmu.2025.1641351

275 views

Original Research

Published on 27 Aug 2025

Laboratory-derived inflammatory ratios as a novel diagnostic model for premature coronary artery disease

in Cardiovascular Endocrinology

Fujia Guo
Min Xu
Qingxian Tu
Heyun Yang
Keqiang Linghu
Botao Li
Jie Zhang
Ya Luo
Hong Huang

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1646944

284 views

Original Research

Published on 27 Aug 2025

Study on the molecular mechanism of matrine in improving rheumatoid arthritis by targeting the NAV2-Wnt3a/β-catenin axis to coordinately regulate the inflammatory-osteolytic loop

in Inflammation

Qianyu Guo
Meie Liang
Zhen Li
Jie Li
Ke Xu
Liyun Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1646918

233 views

Original Research

Published on 27 Aug 2025

Isolated hypoxic pelvic perfusion combined with electroporation is a valid alternative to traditional therapies for anal squamous cell carcinoma: a case study

in Gastrointestinal Cancers: Colorectal Cancer

Karl R. Aigner
Kornelia Aigner
Marc J. H. Hendrikx
Abderrahmane Bekrentchir
Hansjörg Aust

Frontiers in Oncology

doi 10.3389/fonc.2025.1644317

216 views

Original Research

Published on 27 Aug 2025

Functional characterization and clinical significance of IGSF8 in pan-cancer: an integrated bioinformatic and experimental study

in Cancer Immunity and Immunotherapy

Jie Wang
Lingxiao Lu
Ruicheng Wu
Dengxiong Li
Zhipeng Wang
Luxia Ye
Dechao Feng

Frontiers in Immunology

doi 10.3389/fimmu.2025.1642193

219 views

Original Research

Published on 27 Aug 2025

Targeted and personalized immunotherapy in lung adenocarcinoma: single-cell RNA sequencing of MAFF+ tumor cells and the therapeutic potential of FOS

in Cancer Immunity and Immunotherapy

Xiangsong Cheng
Shu Chen
Yilong Fu
Runze Jiang
Yanlong Jing
Bizhu Zhao
Dong Guo
Liangyu Wang
Zi Ye
Yumeng Li

Frontiers in Immunology

doi 10.3389/fimmu.2025.1649147

369 views

Original Research

Published on 27 Aug 2025

Epidemiological research on diabetic nephropathy at global, regional, and national levels from 1990 to 2021: an analysis derived from the global burden of disease 2021 study

in Clinical Diabetes

Lu Zhang
Liangliang Jiang
Rong Xu
Xuemei Zhang
Boxun Zhang
Rensong Yue

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1647064

374 views

Perspective

Published on 27 Aug 2025

Towards language justice: queering solidarities between interpreters, service providers, and community members

in Culture and Communication

Mikhael Touma
Frankie Hanman-Siegersma
Blossom Ah Ket
Paige Matthews
Monica Quijano de Brasdefer

Frontiers in Communication

doi 10.3389/fcomm.2025.1592003

345 views

Case Report

Published on 27 Aug 2025

Autoimmune GFAP astrocytopathy manifesting as sintilimab-induced myelitis: a Case Report and literature review

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Xue Ma
Xing Qin

Frontiers in Immunology

doi 10.3389/fimmu.2025.1595653

208 views

Review

Published on 27 Aug 2025

USP38: an important regulatory factor in tumor malignant progression

in Cancer Immunity and Immunotherapy

Junyan Li
Jinghua Zhong
Jianming Ye
Yi Xiang
Qiang Yi
Gangfeng Zhu
Shifan Deng
Xiangcai Wang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1612723

220 views

Original Research

Published on 27 Aug 2025

Identification of key genes associated with perineural invasion in stage II colorectal cancer and their prognostic implications

in Gastrointestinal Cancers: Colorectal Cancer

Chen Chang
Bin Zhang
Jingli Chen
Guorong Wang

Frontiers in Oncology

doi 10.3389/fonc.2025.1612143

160 views

Articles

Recurrent rectal cancer cured by transsacral prone longitudinal incision combined with bilateral gluteus maximus “kite” flap filling: a case report

A faked prolongation of an endurance target time does not affect muscle fatigue but increases perceived exertion

Corneal stromal microdots accumulation and its association with corneal neurodegeneration and retinal microvascular perfusion in diabetes

CEACAM6 as a machine learning derived immune biomarker for predicting neoadjuvant chemotherapy response in HR+/HER2− breast cancer

Association of neonatal hypothermia with neonatal hypoglycemia

A genetically determined molecular switch modulates the anti-inflammatory potential of human IgA

Laboratory-derived inflammatory ratios as a novel diagnostic model for premature coronary artery disease

Study on the molecular mechanism of matrine in improving rheumatoid arthritis by targeting the NAV2-Wnt3a/β-catenin axis to coordinately regulate the inflammatory-osteolytic loop

Isolated hypoxic pelvic perfusion combined with electroporation is a valid alternative to traditional therapies for anal squamous cell carcinoma: a case study

Functional characterization and clinical significance of IGSF8 in pan-cancer: an integrated bioinformatic and experimental study

Targeted and personalized immunotherapy in lung adenocarcinoma: single-cell RNA sequencing of MAFF+ tumor cells and the therapeutic potential of FOS

Epidemiological research on diabetic nephropathy at global, regional, and national levels from 1990 to 2021: an analysis derived from the global burden of disease 2021 study

Towards language justice: queering solidarities between interpreters, service providers, and community members

Autoimmune GFAP astrocytopathy manifesting as sintilimab-induced myelitis: a Case Report and literature review

USP38: an important regulatory factor in tumor malignant progression

Identification of key genes associated with perineural invasion in stage II colorectal cancer and their prognostic implications