Deep Space | List of Frontiers open access articles

Original Research

Published on 01 Oct 2025

Prenatal Poly I:C exposure affects tryptophan-kynurenine metabolism associated with intestinal microbiome in female juvenile rats

in Microbial Immunology

Lirong Yang
Huiyu Chen
Menglu Zeng
Yanfang Lu
Chen Xu
Zhenju Cao
Fuchun Zhong
Xinyu Yang
Anying Shen
Yueqing Su

Frontiers in Immunology

doi 10.3389/fimmu.2025.1669845

584 views

Original Research

Published on 01 Oct 2025

Effects of manual carotid compression in endovascular thrombectomy for acute anterior circulation large-vessel occlusion: a multicenter, propensity score-matching study

in Stroke

Li Bao
Shuang He

Frontiers in Neurology

doi 10.3389/fneur.2025.1669778

294 views

Perspective

Published on 01 Oct 2025

Organs-on-a-chip for global equity: a perspective from Guatemala on advancing biomedical research in resource-limited settings

in Organ on a Chip

Maria D. Cabrera
Andrea C. del Valle

Frontiers in Lab on a Chip Technologies

doi 10.3389/frlct.2025.1669220

447 views

Review

Published on 01 Oct 2025

Insulin resistance, metabolic syndrome and polycystic ovaries: an intriguing conundrum

in Pediatric Endocrinology

Sara Prosperi
Francesco Chiarelli

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1669716

935 views

Original Research

Published on 01 Oct 2025

Multimodal therapeutic options for esophageal perforations—a single-center experience

in Visceral Surgery

Maximilian Gruber
Lars Kollmann
Johan Friso Lock
Sven Flemming
Stanislaus Reimer
Markus Brand
Armin Wiegering
Alexander Meining
Ivan Aleksic
Christoph-Thomas Germer

Frontiers in Surgery

doi 10.3389/fsurg.2025.1662261

292 views

Mini Review

Published on 01 Oct 2025

Microbiome-mediated regulation of chemoradiotherapy response

in Cancer Immunity and Immunotherapy

Lan Zhou
Benhua Li
Juan Ren
Shoujin Wang
Jun Wang

Frontiers in Oncology

doi 10.3389/fonc.2025.1659467

633 views

Original Research

Published on 01 Oct 2025

Dogme 25: media primitivism and new auteurism in the age of artificial intelligence

in Media, Creative, and Cultural Industries

Zhiqiang Sui
Shuqin Wang

Frontiers in Communication

doi 10.3389/fcomm.2025.1659731

608 views

Original Research

Published on 01 Oct 2025

Efficiency and equity of resource allocation in healthcare services using DEA and concentration indices: evidence from the traditional medicine hospital in Gansu Province, China

in Health Economics

Yahui Ba
Zhonghua Luo

Frontiers in Public Health

doi 10.3389/fpubh.2025.1674348

643 views

Original Research

Published on 01 Oct 2025

METTL3-mediated activation of Sonic Hedgehog signaling promotes breast cancer progression

in Cellular Biochemistry

Sunanda Baidya
Utpal Barua
Muntasim Rahman Shanto
Tayeba Sultana Sonia
Md. Al Amin
Saima Sultana
Nusrat Jerin
Khadiza Jahan
Israt Jahan
Shakera Ahmed

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1674339

2,147 views

Brief Research Report

Published on 01 Oct 2025

Single-cell profiling deciphering cholesterol metabolism dysregulation in metastatic uveal melanoma and implicating SLC45A2 in its prognosis

in Cancer Immunity and Immunotherapy

Yiming Zhou
Yuan Cao
Zhaohui Li
Xinlan Lei
Qiao Gao
Wen Yao
Jian Guan
Guojing Lu
Haiyu Deng
Lanyue Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1660268

327 views

Original Research

Published on 01 Oct 2025

The influence of diamond-mining industry waste on soil geochemistry and the development of salinization processes

in Toxicology, Pollution and the Environment

Tatiana Vasileva
Yana Legostaeva
Olesya Shadrinova
Egor Ivanov

Frontiers in Environmental Science

doi 10.3389/fenvs.2025.1660339

675 views

Perspective

Published on 01 Oct 2025

The engagement of people with lived experiences in substance use research

in Substance Use Disorders and Behavioral Addictions

Catherine Kim

Frontiers in Public Health

doi 10.3389/fpubh.2025.1611836

406 views

Original Research

Published on 01 Oct 2025

STEM career: essential factors for students to achieve success in STEM (supportive individuals, skills/abilities, motivational factors)

in STEM Education

Mariana Dogaru
Mirela Cristina Negreanu
Olivia Pisicǎ
Alina Florentina Pîrvu

Frontiers in Education

doi 10.3389/feduc.2025.1611178

531 views

Original Research

Published on 01 Oct 2025

Heart disease prediction with a feature-sensitized interpretable framework for the Internet of Medical Things sensors

in Connected Health

Nallakaruppan Kailasanathan
Gangadevi Ezhilarasan
Shitharth Selvarajan
Rajesh Kumar Dhanaraj
Dragan Pamucar
Nathan Shankar

Frontiers in Digital Health

doi 10.3389/fdgth.2025.1612915

594 views

Case Report

Published on 01 Oct 2025

Clinical features and genetic analysis of acrodermatitis enteropathica in an ethnic minority infant from Western China: a case report and literature review

in Dermatology

Tuerhongjiang Axirejiang
Gulinigeer Simayi
Abudushalamu Abuduwake
Yunxia Liu
Gang Zheng
Irshat Ibrahim

Frontiers in Medicine

doi 10.3389/fmed.2025.1616196

319 views

Original Research

Published on 01 Oct 2025

The effect of empathy intervention and VR exergames on social anxiety in left-behind children

in Health Psychology

Zhiyan Xiao
Dianhui Peng
Chunxia Lu
Xueqin Zhuang

Frontiers in Psychology

doi 10.3389/fpsyg.2025.1595174

575 views

Articles

Prenatal Poly I:C exposure affects tryptophan-kynurenine metabolism associated with intestinal microbiome in female juvenile rats

Effects of manual carotid compression in endovascular thrombectomy for acute anterior circulation large-vessel occlusion: a multicenter, propensity score-matching study

Organs-on-a-chip for global equity: a perspective from Guatemala on advancing biomedical research in resource-limited settings

Insulin resistance, metabolic syndrome and polycystic ovaries: an intriguing conundrum

Multimodal therapeutic options for esophageal perforations—a single-center experience

Microbiome-mediated regulation of chemoradiotherapy response

Dogme 25: media primitivism and new auteurism in the age of artificial intelligence

Efficiency and equity of resource allocation in healthcare services using DEA and concentration indices: evidence from the traditional medicine hospital in Gansu Province, China

METTL3-mediated activation of Sonic Hedgehog signaling promotes breast cancer progression

Single-cell profiling deciphering cholesterol metabolism dysregulation in metastatic uveal melanoma and implicating SLC45A2 in its prognosis

The influence of diamond-mining industry waste on soil geochemistry and the development of salinization processes

The engagement of people with lived experiences in substance use research

STEM career: essential factors for students to achieve success in STEM (supportive individuals, skills/abilities, motivational factors)

Heart disease prediction with a feature-sensitized interpretable framework for the Internet of Medical Things sensors

Clinical features and genetic analysis of acrodermatitis enteropathica in an ethnic minority infant from Western China: a case report and literature review

The effect of empathy intervention and VR exergames on social anxiety in left-behind children