Digestive Enzymes | List of Frontiers open access articles

Original Research

Published on 27 Aug 2025

Functional characterization and clinical significance of IGSF8 in pan-cancer: an integrated bioinformatic and experimental study

in Cancer Immunity and Immunotherapy

Jie Wang
Lingxiao Lu
Ruicheng Wu
Dengxiong Li
Zhipeng Wang
Luxia Ye
Dechao Feng

Frontiers in Immunology

doi 10.3389/fimmu.2025.1642193

219 views

Original Research

Published on 27 Aug 2025

Targeted and personalized immunotherapy in lung adenocarcinoma: single-cell RNA sequencing of MAFF+ tumor cells and the therapeutic potential of FOS

in Cancer Immunity and Immunotherapy

Xiangsong Cheng
Shu Chen
Yilong Fu
Runze Jiang
Yanlong Jing
Bizhu Zhao
Dong Guo
Liangyu Wang
Zi Ye
Yumeng Li

Frontiers in Immunology

doi 10.3389/fimmu.2025.1649147

369 views

Original Research

Published on 27 Aug 2025

Epidemiological research on diabetic nephropathy at global, regional, and national levels from 1990 to 2021: an analysis derived from the global burden of disease 2021 study

in Clinical Diabetes

Lu Zhang
Liangliang Jiang
Rong Xu
Xuemei Zhang
Boxun Zhang
Rensong Yue

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1647064

374 views

Perspective

Published on 27 Aug 2025

Towards language justice: queering solidarities between interpreters, service providers, and community members

in Culture and Communication

Mikhael Touma
Frankie Hanman-Siegersma
Blossom Ah Ket
Paige Matthews
Monica Quijano de Brasdefer

Frontiers in Communication

doi 10.3389/fcomm.2025.1592003

345 views

Case Report

Published on 27 Aug 2025

Autoimmune GFAP astrocytopathy manifesting as sintilimab-induced myelitis: a Case Report and literature review

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Xue Ma
Xing Qin

Frontiers in Immunology

doi 10.3389/fimmu.2025.1595653

208 views

Review

Published on 27 Aug 2025

USP38: an important regulatory factor in tumor malignant progression

in Cancer Immunity and Immunotherapy

Junyan Li
Jinghua Zhong
Jianming Ye
Yi Xiang
Qiang Yi
Gangfeng Zhu
Shifan Deng
Xiangcai Wang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1612723

220 views

Original Research

Published on 27 Aug 2025

Identification of key genes associated with perineural invasion in stage II colorectal cancer and their prognostic implications

in Gastrointestinal Cancers: Colorectal Cancer

Chen Chang
Bin Zhang
Jingli Chen
Guorong Wang

Frontiers in Oncology

doi 10.3389/fonc.2025.1612143

160 views

Review

Published on 27 Aug 2025

Evaluating the safety and efficacy of SILS and SILS+1 port laparoscopic surgery for colorectal resection: a systematic review with meta-analysis and trial sequential analysis of RCTs

in Gastrointestinal Cancers: Colorectal Cancer

Kai Lu
Shilong Shu
Furui Zhong
Hua Yang
Yong Cheng
Faqiang Zhang

Frontiers in Oncology

doi 10.3389/fonc.2025.1605040

215 views

Original Research

Published on 27 Aug 2025

Large-scale statistical mapping of T-cell receptor β sequences to human leukocyte antigens

in T Cell Biology

H. Jabran Zahid
Ruth Taniguchi
Peter Ebert
I-Ting Chow
Chris Gooley
Jinpeng Lv
Lorenzo Pisani
Mikaela Rusnak
Rebecca Elyanow
Hiroyuki Takamatsu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1603730

253 views

Mini Review

Published on 27 Aug 2025

Immunosuppressive tumor microenvironment and advance in immunotherapy in melanoma bone metastasis

in Cancer Immunity and Immunotherapy

Yiqun Ma
Lin Zhang
Weimin Liu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1608215

383 views

Original Research

Published on 27 Aug 2025

A novel prognostic biomarker DUSP6 promote the malignant progression of bladder cancer through mTOR mediated mitophagy

in Genitourinary Oncology

Jianbiao Huang
Chongwei Zhou
Zhaojun Yu
Zhen Song
Huanhuan Deng
Haichao Chao
Tao Zeng

Frontiers in Oncology

doi 10.3389/fonc.2025.1603069

309 views

Original Research

Published on 27 Aug 2025

Early-life undernutrition, immune dysregulation, and cancer incidence in later life: a national life-course analysis from the China health and retirement longitudinal study

in Nutritional Immunology

Hailin Wang
Changkang Wu
Xuancheng Zhou
Gang Huang
Jingdong Li
Xiaowei Tang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1602290

313 views

Systematic Review

Published on 27 Aug 2025

Prognostic significance of prognostic nutritional index in patients with head and neck squamous cell carcinoma

in Cancer Immunity and Immunotherapy

Yongping Wang
Jie Wang
Binbin Xiao
Yuqing Wang
Fu Huang
Yang Jiang
Tianyi Liu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1597965

165 views

Case Report

Published on 27 Aug 2025

Case Report: Complete response to pembrolizumab monotherapy in a geriatric patient with metastatic Merkel cell carcinoma and TNBC

in Skin Cancer

Jessica Liu
Kelly Olino
Maryam Lustberg
Jane Kanowitz

Frontiers in Oncology

doi 10.3389/fonc.2025.1579287

372 views

Original Research

Published on 27 Aug 2025

Multi-omics modality completion and knowledge distillation for drug response prediction in cervical cancer

in Gynecological Oncology

DongZi Li
Bowei Yan
Kai Liao
Jian Huang
Jing Zhang
YiChen Chen
Jue Zhu
Shuang Zhi
Pingli Chen

Frontiers in Oncology

doi 10.3389/fonc.2025.1622600

141 views

Methods

Published on 27 Aug 2025

Bridging the gap between water-saving technologies and adoption in vegetable farming: insights from Florida, USA

in Field Water Management

Akshara Athelly
Sandra M. Guzmán
Ziwen Yu
Jonathan Adam Watson

Frontiers in Agronomy

doi 10.3389/fagro.2025.1622260

398 views

Articles

Functional characterization and clinical significance of IGSF8 in pan-cancer: an integrated bioinformatic and experimental study

Targeted and personalized immunotherapy in lung adenocarcinoma: single-cell RNA sequencing of MAFF+ tumor cells and the therapeutic potential of FOS

Epidemiological research on diabetic nephropathy at global, regional, and national levels from 1990 to 2021: an analysis derived from the global burden of disease 2021 study

Towards language justice: queering solidarities between interpreters, service providers, and community members

Autoimmune GFAP astrocytopathy manifesting as sintilimab-induced myelitis: a Case Report and literature review

USP38: an important regulatory factor in tumor malignant progression

Identification of key genes associated with perineural invasion in stage II colorectal cancer and their prognostic implications

Evaluating the safety and efficacy of SILS and SILS+1 port laparoscopic surgery for colorectal resection: a systematic review with meta-analysis and trial sequential analysis of RCTs

Large-scale statistical mapping of T-cell receptor β sequences to human leukocyte antigens

Immunosuppressive tumor microenvironment and advance in immunotherapy in melanoma bone metastasis

A novel prognostic biomarker DUSP6 promote the malignant progression of bladder cancer through mTOR mediated mitophagy

Early-life undernutrition, immune dysregulation, and cancer incidence in later life: a national life-course analysis from the China health and retirement longitudinal study

Prognostic significance of prognostic nutritional index in patients with head and neck squamous cell carcinoma

Case Report: Complete response to pembrolizumab monotherapy in a geriatric patient with metastatic Merkel cell carcinoma and TNBC

Multi-omics modality completion and knowledge distillation for drug response prediction in cervical cancer

Bridging the gap between water-saving technologies and adoption in vegetable farming: insights from Florida, USA