Downstream Development | List of Frontiers open access articles

Original Research

Published on 04 Mar 2026

Mental health of caregivers for people with dementia and cerebral palsy as a key determinant of caregiver burden: a multivariable analysis

in Public Mental Health

Alba Sánchez-Gil
Andrea Calleja-Caballero
Fátima Pérez-Robledo
Carlos Martín-Sánchez
María Rodríguez-Lorenzo
María Martínez-Romo
Enrique Pérez-Saez
Pedro Manuel Rodríguez-Muñoz
Cristina Rivera-Picón
Jesus Perez

Frontiers in Public Health

doi 10.3389/fpubh.2026.1757413

Original Research

Published on 04 Mar 2026

Prevalence and associated factors of thyroid nodules in a health examination cohort: an ultrasound-based cross-sectional study using electronic health records

in Environmental Health and Exposome

Lele Meng
Xueying Zhang

Frontiers in Public Health

doi 10.3389/fpubh.2026.1752140

Original Research

Published on 04 Mar 2026

CRISPR/Cas9-mediated knockout of DFR alters pigmentation and shifts flavonoid accumulation in red leaf lettuce without detectable growth penalties

in Genome Editing in Plants

Ai Nagamine
Masaki Ono
Osuke Sato
Eiji Goto
Hiroshi Ezura

Frontiers in Genome Editing

doi 10.3389/fgeed.2026.1755922

107 views

Original Research

Published on 04 Mar 2026

Implementation status and quality improvement strategies of the record-filing system for drug clinical trial institutions in Sichuan Province

in Regulatory Science

Shangyuan Qin
Houfeng Zhou

Frontiers in Medicine

doi 10.3389/fmed.2026.1755380

Original Research

Published on 04 Mar 2026

Accuracy of novel custom 3D-printed metal and polymer cutting guides for segmental mandibulectomy in the dog: a cadaveric study

in Veterinary Surgery

Rachel McKay
Marine Traverson
Caroline Alting
Satyanarayana Konala
Erin Perry
Angelica Luzzi
Ken Gall

Frontiers in Veterinary Science

doi 10.3389/fvets.2026.1780938

Brief Research Report

Published on 04 Mar 2026

Sex differences in vaccine-induced immunity in mice immunized with integrase-defective lentiviral vector delivering the SARS-CoV-2 Spike protein

in Vaccines and Molecular Therapeutics

Iole Farina
Alessandra Gallinaro
Martina Borghi
Maria Franca Pirillo
Chiara Falce
Andrea Canitano
Zuleika Michelini
Alice Zappitelli
Antonio Di Virgilio
Mario Picozza

Frontiers in Immunology

doi 10.3389/fimmu.2026.1778067

104 views

Original Research

Published on 04 Mar 2026

The relationship between Tai Chi practice, Psychological Resilience, and depression in older adults: an integrated study of mediation and network analysis

in Aging and Public Health

Faxiang Fan
Hao Gou
Ping Li
Luyao Xiang
Jingtao Du

Frontiers in Public Health

doi 10.3389/fpubh.2026.1777392

Original Research

Published on 04 Mar 2026

A foundation model-based multi-instance learning framework for accurate prediction of lymph node metastasis in prostate cancer from whole slide images

in Genitourinary Oncology

Guang Zeng
Weiwei Li
Haonan Mei
Ran Du

Frontiers in Oncology

doi 10.3389/fonc.2026.1775750

194 views

Original Research

Published on 04 Mar 2026

Long-term survival and the critical role of competing risks in pneumoconiosis: a large-scale retrospective cohort study

in Occupational Health and Safety

Xinlei Chu
Lang Zhou
Qing Zhou
Lei Chen
Han Liu
Yao Huang
Wenjian Tan
Wei Li
Ning Wang
Lei Han

Frontiers in Public Health

doi 10.3389/fpubh.2026.1782032

152 views

Review

Published on 04 Mar 2026

Macrophage plasticity in thyroid eye disease: dual effects of inflammation and fibrosis

in Inflammation

Xinyu Li
Zhangjun Ren
Lanlan Gao
Chao Xiong
Hongfei Liao

Frontiers in Immunology

doi 10.3389/fimmu.2026.1782204

Original Research

Published on 04 Mar 2026

Low initial body fat percentage exacerbates skeletal muscle loss and increases the risk of hyperuricemia during high-altitude acclimatization in young men

in Nutrition and Metabolism

Yanlin Zhu
Jie He
Shuang Li
Jie Zhang
Huichang Jia
Yongjian Yang
Yi Li
Xianglian Li
Jian Li
Yunming Li

Frontiers in Nutrition

doi 10.3389/fnut.2026.1781965

Original Research

Published on 04 Mar 2026

Technostress in Spain between 2016 and 2024: perception of the impact of teleworking on the health of Spanish workers

in Organizational Psychology

Agustin Sánchez-Toledo Ledesma

Frontiers in Psychology

doi 10.3389/fpsyg.2026.1774427

121 views

Original Research

Published on 04 Mar 2026

Low-cost mobile laser scanning for urban tree assessment: accuracy evaluation and application potential

in Lidar Sensing

Jozef Výbošťok
Juliána Chudá
Daniel Tomčík
Michal Skladan
Arunima Singh
Roman Kadlečík
František Chudý
Daniel Kükenbrink
Martin Mokroš
Janusz Bedkowski

Frontiers in Remote Sensing

doi 10.3389/frsen.2026.1774149

392 views

Original Research

Published on 04 Mar 2026

Clinical outcomes and revision strategies following failed internal fixation of peri-trochanteric femoral fractures: a retrospective cohort study

in Geriatric Medicine

Yujie Zhang
Fan Yang
Chaorong Yu
Hanxiao Zhu
Erman Chen
Hang Li
Weixu Li

Frontiers in Medicine

doi 10.3389/fmed.2026.1773816

152 views

Original Research

Published on 04 Mar 2026

Golden ratio organization in human EEG is associated with theta-alpha frequency convergence: a multi-dataset validation study

in Brain Imaging and Stimulation

Andrei Ursachi

Frontiers in Human Neuroscience

doi 10.3389/fnhum.2026.1781338

368 views

Review

Published on 04 Mar 2026

Oral microbiome dysbiosis in autism spectrum disorder: the oral-gut-brain axis and future perspectives: a narrative review

in Microorganisms in Vertebrate Digestive Systems

YongMao Huang
QiuYing Liang
Youjin Shen
Junjie Chen
Wenan Xu

Frontiers in Microbiology

doi 10.3389/fmicb.2026.1783810

Articles

Mental health of caregivers for people with dementia and cerebral palsy as a key determinant of caregiver burden: a multivariable analysis

Prevalence and associated factors of thyroid nodules in a health examination cohort: an ultrasound-based cross-sectional study using electronic health records

CRISPR/Cas9-mediated knockout of DFR alters pigmentation and shifts flavonoid accumulation in red leaf lettuce without detectable growth penalties

Implementation status and quality improvement strategies of the record-filing system for drug clinical trial institutions in Sichuan Province

Accuracy of novel custom 3D-printed metal and polymer cutting guides for segmental mandibulectomy in the dog: a cadaveric study

Sex differences in vaccine-induced immunity in mice immunized with integrase-defective lentiviral vector delivering the SARS-CoV-2 Spike protein

The relationship between Tai Chi practice, Psychological Resilience, and depression in older adults: an integrated study of mediation and network analysis

A foundation model-based multi-instance learning framework for accurate prediction of lymph node metastasis in prostate cancer from whole slide images

Long-term survival and the critical role of competing risks in pneumoconiosis: a large-scale retrospective cohort study

Macrophage plasticity in thyroid eye disease: dual effects of inflammation and fibrosis

Low initial body fat percentage exacerbates skeletal muscle loss and increases the risk of hyperuricemia during high-altitude acclimatization in young men

Technostress in Spain between 2016 and 2024: perception of the impact of teleworking on the health of Spanish workers

Low-cost mobile laser scanning for urban tree assessment: accuracy evaluation and application potential

Clinical outcomes and revision strategies following failed internal fixation of peri-trochanteric femoral fractures: a retrospective cohort study

Golden ratio organization in human EEG is associated with theta-alpha frequency convergence: a multi-dataset validation study

Oral microbiome dysbiosis in autism spectrum disorder: the oral-gut-brain axis and future perspectives: a narrative review