Drug Metabolizing Enzyme | List of Frontiers open access articles

Original Research

Published on 19 Jun 2024

Development of radioiodine-labeled mequitazine for evaluation of hepatic CYP2D activity

in Drug Metabolism and Transport

Asuka Mizutani
Masato Kobayashi
Kodai Nishi
Ken-ichi Fujita
Kotaro Takahashi
Yuka Muranaka
Kakeru Sato
Masanori Kitamura
Chie Suzuki
Ryuichi Nishii

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1397288

2,007 views

Mini Review

Published on 24 Oct 2022

Inflammatory signaling on cytochrome P450-mediated drug metabolism in hepatocytes

in Inflammation Pharmacology

Xiaokang Wang
Jiaoyu Rao
Zhiyi Tan
Tianrong Xun
Jingqian Zhao
Xixiao Yang

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1043836

11,581 views
50 citations

Mini Review

Published on 08 Sep 2025

Interaction between gut microbiota and anesthesia: mechanism exploration and translation challenges focusing on the gut-brain-liver axis

in Intestinal Microbiome

Ruolan Zhang
Li Li
Gaojie Yu
Yang Li
Kexi Wei
Liang Lin
Yifeng Ye

Frontiers in Cellular and Infection Microbiology

doi 10.3389/fcimb.2025.1626585

3,259 views
3 citations

Original Research

Published on 27 Feb 2023

Practice of CYP450 genotyping and phenotyping in children in a real-life setting

in Pharmacogenetics and Pharmacogenomics

Frédérique Rodieux
Youssef Daali
Victoria Rollason
Caroline F. Samer
Kuntheavy Ing Lorenzini

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1130100

4,197 views
8 citations

Original Research

Published on 22 Feb 2022

Use of a Baculovirus-Mammalian Cell Expression-System for Expression of Drug-Metabolizing Enzymes: Optimization of Infection With a Focus on Cytochrome P450 3A4

in Pharmacogenetics and Pharmacogenomics

Yuu Miyauchi
Akane Kimura
Madoka Sawai
Keiko Fujimoto
Yuko Hirota
Yoshitaka Tanaka
Shinji Takechi
Peter I. Mackenzie
Yuji Ishii

Frontiers in Pharmacology

doi 10.3389/fphar.2022.832931

9,432 views
5 citations

Original Research

Published on 04 Mar 2022

Drug Transporters ABCB1 (P-gp) and OATP, but not Drug-Metabolizing Enzyme CYP3A4, Affect the Pharmacokinetics of the Psychoactive Alkaloid Ibogaine and its Metabolites

in Drug Metabolism and Transport

Margarida L. F. Martins
Paniz Heydari
Wenlong Li
Alejandra Martínez-Chávez
Nikkie Venekamp
Maria C. Lebre
Luc Lucas
Jos H. Beijnen
Alfred H. Schinkel

Frontiers in Pharmacology

doi 10.3389/fphar.2022.855000

5,501 views
7 citations

Articles

Development of radioiodine-labeled mequitazine for evaluation of hepatic CYP2D activity

Inflammatory signaling on cytochrome P450-mediated drug metabolism in hepatocytes

Interaction between gut microbiota and anesthesia: mechanism exploration and translation challenges focusing on the gut-brain-liver axis

Practice of CYP450 genotyping and phenotyping in children in a real-life setting

Use of a Baculovirus-Mammalian Cell Expression-System for Expression of Drug-Metabolizing Enzymes: Optimization of Infection With a Focus on Cytochrome P450 3A4

Drug Transporters ABCB1 (P-gp) and OATP, but not Drug-Metabolizing Enzyme CYP3A4, Affect the Pharmacokinetics of the Psychoactive Alkaloid Ibogaine and its Metabolites