Ed95 | List of Frontiers open access articles

Original Research

Published on 18 Mar 2025

Effective doses of remimazolam and esketamine combined with remifentanil for endotracheal intubation without muscle relaxants in pediatric patients

in Obstetric and Pediatric Pharmacology

Jinming Chen
Ying Mai
Xiaolei Cheng
Hao Sun
Zhihong Chen
Zhongqi Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1558966

3,002 views
4 citations

Clinical Trial

Published on 30 May 2023

Determination of the 95% effective dose of remimazolam tosylate in anesthesia induction inhibits endotracheal intubation response in senile patients

in Drugs Outcomes Research and Policies

Liangchao Qu
Mei Liu
Ru Ouyang
Tianyuan Li
Dingde Long
Yao Jiang
Chengyu Wang
Liqin Cheng

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1136003

4,232 views
13 citations

Clinical Trial

Published on 03 Jul 2023

Dose–response study of prophylactic nitroglycerin for prevention of pituitrin-induced hypertension during laparoscopic myomectomy: a prospective, randomized study

in Intensive Care Medicine and Anesthesiology

Jin Wang
Qiang Xu
Fei Xiao
Gang Chen

Frontiers in Medicine

doi 10.3389/fmed.2023.1186041

2,592 views
3 citations

Original Research

Published on 23 Aug 2023

ED95 of remimazolam in nasal administration for attenuating preoperative anxiety in children

in Intensive Care Medicine and Anesthesiology

Xiang Long
Li-xia Wen
Hu Yang
Guo-hong Zhu
Qing-yun Zhang
Jing-jing Jiang
Yuan Gong

Frontiers in Medicine

doi 10.3389/fmed.2023.1253738

4,587 views
23 citations

Clinical Trial

Published on 24 Jul 2025

ED50 and ED95 of hypobaric ropivacaine during unilateral spinal anesthesia in older patients undergoing hip replacement surgery

in Intensive Care Medicine and Anesthesiology

Chao Lin
Wen-Lin Xian
Jun Xu
Ting Zhao
Zhi-Qiang Wu
Fang-Jun Wang

Frontiers in Medicine

doi 10.3389/fmed.2025.1571574

1,770 views
2 citations

Original Research

Published on 20 Mar 2024

Effective dose of intranasal remimazolam for preoperative sedation in preschool children: a dose-finding study using Dixon’s up-and-down method

in Obstetric and Pediatric Pharmacology

Ming-Jie Ni
Yu-Ting Jin
Qian-Lin Wu
Ning Zhang
Jia-He Tian
Jun Li
Kai-Ming Yuan

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1372139

4,274 views
16 citations

Original Research

Published on 20 Sep 2022

Effective dose of propofol combined with a low-dose esketamine for gastroscopy in elderly patients: A dose finding study using dixon’s up-and-down method

in Gastrointestinal and Hepatic Pharmacology

Yuling Zheng
Yafei Xu
Bixin Huang
Ying Mai
Yiwen Zhang
Zhongqi Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2022.956392

4,666 views
25 citations

Original Research

Published on 19 Sep 2019

Optimal Dexmedetomidine Dose to Prevent Emergence Agitation Under Sevoflurane and Remifentanil Anesthesia During Pediatric Tonsillectomy and Adenoidectomy

in Obstetric and Pediatric Pharmacology

Yan-zhuo Zhang
Xue Wang
Jia-min Wu
Chun-yu Song
Xiao-guang Cui

Frontiers in Pharmacology

doi 10.3389/fphar.2019.01091

12,036 views
29 citations

Clinical Trial

Published on 16 Dec 2024

Determining the effective dose of esketamine combined with propofol for painless hysteroscopy: a prospective dose-finding study

in Neuropharmacology

Zhimin Sheng
Xiang Liu
Kang Lin
Jie Liu
Junqin Mao
Xiaowei Qian

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1419732

2,129 views
4 citations

Original Research

Published on 20 Apr 2023

Determination of the effective dose of dexmedetomidine to achieve loss of consciousness during anesthesia induction

in Intensive Care Medicine and Anesthesiology

Bing Mu
Wenjie Xu
Hongyi Li
Zizheng Suo
Xiaoxiao Wang
Yuxiang Zheng
Yi Tian
Bowen Zhang
Jie Yu
Naiyuan Tian

Frontiers in Medicine

doi 10.3389/fmed.2023.1158085

5,972 views
5 citations

Clinical Trial

Published on 20 Sep 2022

The median effective doses of propofol combined with two different doses of nalbuphine for adult patients during painless gastroscopy

in Gastrointestinal and Hepatic Pharmacology

Lili Tang
Chenxuan Ye
Nan Wang
Chen Chen
Sirui Chen
Shan Gao
Xuesheng Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1014486

4,330 views
16 citations

Original Research

Published on 06 Jan 2025

Median effective dose of remimazolam combined with sufentanil for inhibiting laryngeal mask airway insertion responses in children of different ages

in Obstetric and Pediatric Pharmacology

Hongyun Li
Jinxia Wang
Rong Wei
Yan Jiang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1506209

2,140 views
5 citations

General Commentary

Published on 20 Jan 2026

Commentary: ED50 and ED95 of hypobaric ropivacaine during unilateral spinal anesthesia in older patients undergoing hip replacement surgery

in Intensive Care Medicine and Anesthesiology

Songfeng Li
Yalin Tian
Shanhuai Tian
Tingdan Tan
Shaojin Bu

Frontiers in Medicine

doi 10.3389/fmed.2025.1724654

367 views

Original Research

Published on 08 Oct 2025

The effective sedative dose of remimazolam for BIS <60 during general anesthesia induction between elderly and non-elderly patients-A randomized controlled trial

in Obstetric and Pediatric Pharmacology

Jun-Li Zheng
Jie-Feng Sun
Qing Han
Si-Ren Shi
Jin Zhou
Wei-Long Wang
Xiao-Dong Huang
Zhen-Feng Zhou

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1692105

2,259 views

Original Research

Published on 29 Jan 2026

Impact of low-dose sufentanil on the effective sedative dose of ciprofol for BIS-guided induction in elderly patients: an up-and-down sequential allocation trial

in Intensive Care Medicine and Anesthesiology

Qing Han
Chun-ming Hu
Jun-li Zheng
Xiao-dong Huang
Pei Chen
Wei-long Wang
Jin Zhou
Zhen-feng Zhou

Frontiers in Medicine

doi 10.3389/fmed.2025.1715148

498 views

Original Research

Published on 25 Sep 2024

The dose of remimazolam combined with sufentanil for the induction of general anesthesia in obese patients undergoing bariatric surgery: an up-and-down sequential allocation trial

in Drugs Outcomes Research and Policies

Minghui Chen
Huiying Wang
Jiajun Sun
Tao Zhang
Xiaoyin Niu
Tingting Zhang
Jian Liu
Xuan Zhao

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1411856

3,706 views
1 citation

Articles

Effective doses of remimazolam and esketamine combined with remifentanil for endotracheal intubation without muscle relaxants in pediatric patients

Determination of the 95% effective dose of remimazolam tosylate in anesthesia induction inhibits endotracheal intubation response in senile patients

Dose–response study of prophylactic nitroglycerin for prevention of pituitrin-induced hypertension during laparoscopic myomectomy: a prospective, randomized study

ED95 of remimazolam in nasal administration for attenuating preoperative anxiety in children

ED50 and ED95 of hypobaric ropivacaine during unilateral spinal anesthesia in older patients undergoing hip replacement surgery

Effective dose of intranasal remimazolam for preoperative sedation in preschool children: a dose-finding study using Dixon’s up-and-down method

Effective dose of propofol combined with a low-dose esketamine for gastroscopy in elderly patients: A dose finding study using dixon’s up-and-down method

Optimal Dexmedetomidine Dose to Prevent Emergence Agitation Under Sevoflurane and Remifentanil Anesthesia During Pediatric Tonsillectomy and Adenoidectomy

Determining the effective dose of esketamine combined with propofol for painless hysteroscopy: a prospective dose-finding study

Determination of the effective dose of dexmedetomidine to achieve loss of consciousness during anesthesia induction

The median effective doses of propofol combined with two different doses of nalbuphine for adult patients during painless gastroscopy

Median effective dose of remimazolam combined with sufentanil for inhibiting laryngeal mask airway insertion responses in children of different ages

Commentary: ED50 and ED95 of hypobaric ropivacaine during unilateral spinal anesthesia in older patients undergoing hip replacement surgery

The effective sedative dose of remimazolam for BIS <60 during general anesthesia induction between elderly and non-elderly patients-A randomized controlled trial

Impact of low-dose sufentanil on the effective sedative dose of ciprofol for BIS-guided induction in elderly patients: an up-and-down sequential allocation trial

The dose of remimazolam combined with sufentanil for the induction of general anesthesia in obese patients undergoing bariatric surgery: an up-and-down sequential allocation trial