Free Play | List of Frontiers open access articles

Original Research

Published on 05 Nov 2025

Pex1 loss-of-function in zebrafish is viable and recapitulates hallmarks of Zellweger spectrum disorders

in Molecular Signalling and Pathways

Ursula Heins-Marroquin
Zlatan Hodzic
Beatriz Soares Carneiro da Silva
Agnes Hendriks
Floriane Gavotto
Marc O. Warmoes
Lisa Schlicker
Samy Omri
Christian Jäger
Enrico Glaab

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1634536

264 views

Case Report

Published on 05 Nov 2025

Case Report: identification of a novel 9.159-kb deletion in a Chinese α-thalassemia family using single molecule real-time technology sequencing

in Genetics of Common and Rare Diseases

Shulin Wu
Zonghui Feng
Fuxiang Jiang
Min Zhao
Peng Jiang
Gang Xiao
Xian Zhang

Frontiers in Genetics

doi 10.3389/fgene.2025.1669814

174 views

Original Research

Published on 05 Nov 2025

The impact of social support on the quality of sports participation among individuals with disabilities: the chain mediating effects of psychological capital and self-esteem

in Movement Science

Jiahui Peng
Li Cao
Feixuan Li
Deqiao Zhou

Frontiers in Psychology

doi 10.3389/fpsyg.2025.1662636

326 views

Original Research

Published on 05 Nov 2025

The mechanism of digital feedback on health information anxiety among older adults: information processing self-efficacy as a mediating variable

in Aging and Public Health

Yang Zhu
Xin Wang
Xiao Zhang
Yan Li
Yepeng Chen

Frontiers in Public Health

doi 10.3389/fpubh.2025.1676970

376 views

Original Research

Published on 05 Nov 2025

Alterations of lipoprotein subfractions in GH-deficient adults

in Pituitary Endocrinology

Balázs Ratku
Hajnalka Lőrincz
Sára Csiha
Lajos Bíró
Annamária Erdei
Eszter Berta
Dóra Ujvárosy
Miklós Bodor
Endre V. Nagy
Zoltán Szabó

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1696426

298 views

Review

Published on 05 Nov 2025

Durvalumab consolidation therapy in patients with stage III small cell lung cancer after concurrent chemoradiation: a China-based cost-effectiveness analysis

in Cancer Immunity and Immunotherapy

Hui Zhang
Yuhang Liu
Bikun Cai
Mengyi Wang
Haonan Li
Hong Wang

Frontiers in Oncology

doi 10.3389/fonc.2025.1643022

430 views

Review

Published on 05 Nov 2025

Exploring the therapeutic potential of phytochemicals apigenin and ellagic acid in managing polycystic ovarian syndrome and its comorbidities: a comprehensive review

in Translational and Clinical Endocrinology

Acharya Balkrishna
Maneesha Rana
Shalini Mishra
Ritik Agrawal
Satyendra Kumar Rajput
Muralikrishnan Dhanasekaran
Mamta Rana
Vedpriya Arya
Ramith Ramu
Ashutosh Upadhayay

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1633377

638 views

Original Research

Published on 05 Nov 2025

The positive effect of perceived social support and moral resilience between moral injury and health-related productivity loss among emergency nurses

in Public Mental Health

Xiaoting Sun
Bingjie Wang
Meiyu Zhu
Daiying Wu
Miaomiao Yang
Chunmei Zhang

Frontiers in Public Health

doi 10.3389/fpubh.2025.1678811

141 views

Systematic Review

Published on 05 Nov 2025

Combined imaging and serum biomarkers in CEUS-guided microwave ablation for hepatocellular carcinoma: A meta-analysis

in Gastrointestinal Cancers: Hepato Pancreatic Biliary Cancers

Xiaoli Zou
Danyi Zhao
Yu Shang
Yu Song
Yimei Deng
Lin Lu

Frontiers in Oncology

doi 10.3389/fonc.2025.1687044

102 views

Original Research

Published on 05 Nov 2025

Severe and/or prolonged COVID-19 in hematologic diseases: clinical implications before and during the omicron era

in Hematologic Malignancies

Akinao Okamoto
Masahiro Yoshida
Senji Kasahara
Takahide Ara
Kazutaka Ozeki
Takanobu Morishita
Daisuke Ikeda
Minoru Kanaya
Tomohiro Kajiguchi
Yasuhiro Suzuki

Frontiers in Oncology

doi 10.3389/fonc.2025.1687204

440 views

Original Research

Published on 05 Nov 2025

Identification and validation of paraptosis-related biomarkers in recurrent miscarriage

in Immunological Tolerance and Regulation

Yunhui Wan
Fang Fang
Qiao Wang
Jia Xu
Pei Zhu
Ying Cui
Lili Hou
Huimin Wang
Xiaoyong Chen

Frontiers in Immunology

doi 10.3389/fimmu.2025.1656650

321 views

Original Research

Published on 05 Nov 2025

The dynamic systemic immuno-inflammatory index: a novel predictor of neoadjuvant chemotherapy response and outcome in high-risk pediatric neuroblastoma

in Pediatric Oncology

Chenglong Zhang
Xiaoyu Wang
Huizhong Niu
Pengju Zhang
Jianlei Geng

Frontiers in Oncology

doi 10.3389/fonc.2025.1671233

133 views

Review

Published on 05 Nov 2025

Bone metastases in pheochromocytomas and paragangliomas: a narrative review of presentation, diagnosis and management

in Cancer Endocrinology

Jorge Eduardo Contreras-Saldarriaga
Melissa Loaiza-Alzate

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1671486

292 views

Review

Published on 05 Nov 2025

What is the need for adrenalectomy in patients with congenital adrenal hyperplasia in the era of CRF1/ACTH inhibitors?

in Adrenal Endocrinology

Olga Fedorova
Henrik Falhammar

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1693063

446 views

Review

Published on 05 Nov 2025

Gut-ovary axis in polycystic ovary syndrome: mechanistic insights and gut microbiota-targeted therapeutic strategies

in Translational and Clinical Endocrinology

Mei Zhao
Danlin Chen
Xiumei Hu
Caiping Xie
Lianwei Xu
Fuhua Zhou

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1684492

181 views

Original Research

Published on 05 Nov 2025

Artificial intelligence-based evaluation of prognostic benefits from immunotherapy plus targeted therapy with or without radiotherapy or TACE in advanced hepatocellular carcinoma

in Pharmacology of Anti-Cancer Drugs

Yuehong Deng
Shiqin Song
Huarong Zhao
Yuqian Yang
Simin Lu
Xueting Li

Frontiers in Oncology

doi 10.3389/fonc.2025.1694565

319 views

Articles

Pex1 loss-of-function in zebrafish is viable and recapitulates hallmarks of Zellweger spectrum disorders

Case Report: identification of a novel 9.159-kb deletion in a Chinese α-thalassemia family using single molecule real-time technology sequencing

The impact of social support on the quality of sports participation among individuals with disabilities: the chain mediating effects of psychological capital and self-esteem

The mechanism of digital feedback on health information anxiety among older adults: information processing self-efficacy as a mediating variable

Alterations of lipoprotein subfractions in GH-deficient adults

Durvalumab consolidation therapy in patients with stage III small cell lung cancer after concurrent chemoradiation: a China-based cost-effectiveness analysis

Exploring the therapeutic potential of phytochemicals apigenin and ellagic acid in managing polycystic ovarian syndrome and its comorbidities: a comprehensive review

The positive effect of perceived social support and moral resilience between moral injury and health-related productivity loss among emergency nurses

Combined imaging and serum biomarkers in CEUS-guided microwave ablation for hepatocellular carcinoma: A meta-analysis

Severe and/or prolonged COVID-19 in hematologic diseases: clinical implications before and during the omicron era

Identification and validation of paraptosis-related biomarkers in recurrent miscarriage

The dynamic systemic immuno-inflammatory index: a novel predictor of neoadjuvant chemotherapy response and outcome in high-risk pediatric neuroblastoma

Bone metastases in pheochromocytomas and paragangliomas: a narrative review of presentation, diagnosis and management

What is the need for adrenalectomy in patients with congenital adrenal hyperplasia in the era of CRF1/ACTH inhibitors?

Gut-ovary axis in polycystic ovary syndrome: mechanistic insights and gut microbiota-targeted therapeutic strategies

Artificial intelligence-based evaluation of prognostic benefits from immunotherapy plus targeted therapy with or without radiotherapy or TACE in advanced hepatocellular carcinoma