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4 articles related to "Fto Inhibitor"

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Articles

Original Research

Published on 04 May 2021

Targeted Inhibition of FTO Demethylase Protects Mice Against LPS-Induced Septic Shock by Suppressing NLRP3 Inflammasome

in Vaccines and Molecular Therapeutics

Jiahui Luo
Faxi Wang
Fei Sun
Tiantian Yue
Qing Zhou
Chunliang Yang
Shanjie Rong
Ping Yang
Fei Xiong
Qilin Yu

Frontiers in Immunology

doi 10.3389/fimmu.2021.663295

11,465 views
68 citations

Original Research

Published on 12 Jan 2026

Small molecule FTO inhibitor MO-I-500 protects differentiated SH-SY5Y neuronal cells from oxidative stress

in Molecular Signalling and Pathways

Denise Greco
Zuzana Čočková
Debanjan Das
Akash S. Mali
Jiří Novotný
Mark J. Olsen
Petr Telenský

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1736173

1,116 views

Original Research

Published on 17 Feb 2023

Targeting fat mass and obesity-associated protein mitigates human colorectal cancer growth in vitro and in a murine model

in Gastrointestinal Cancers: Colorectal Cancer

Thuy Phan
Vu H. Nguyen
Rui Su
Yangchan Li
Ying Qing
Hanjun Qin
Hyejin Cho
Lei Jiang
Xiwei Wu
Jianjun Chen

Frontiers in Oncology

doi 10.3389/fonc.2023.1087644

5,867 views
14 citations

Original Research

Published on 18 Dec 2024

The N6-methyladenosine RNA epigenetic modification modulates the amplification of coxsackievirus B1 in human pancreatic beta cells

in Virology

Maressa Fernandes Bonfim
Camille Aitchedji
Flore Van Goethem
Lionel Sauvage
Thibault Poinsot
Emilie Calonne
Rachel Deplus
François Fuks
Decio L. Eizirik
Anne Op de Beeck

Frontiers in Microbiology

doi 10.3389/fmicb.2024.1501061

3,327 views
1 citation