Original Research
Published on 07 Oct 2022
SeDeM tool-driven full factorial design for osmotic drug delivery of tramadol HCl: Formulation development, physicochemical evaluation, and in-silico PBPK modeling for predictive pharmacokinetic evaluation using GastroPlus™
in Drug Metabolism and Transport
Frontiers in Pharmacology
doi 10.3389/fphar.2022.974715
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