Functional Optimization | List of Frontiers open access articles

Original Research

Published on 04 Mar 2026

Uncovering the mechanism of arecoline’s effect on oral submucous fibrosis: integrating transcriptomics and in vitro and in vivo experiments

in Craniofacial Biology and Dental Research

Zhenkui Liu
Jian Yi
Fanzuo Zeng
Bowei Chen
Wanling Ning
Jiongwei Tang
Yin OuYang

Frontiers in Physiology

doi 10.3389/fphys.2026.1768602

Review

Published on 04 Mar 2026

Therapeutic modulation of empathy: pharmacological, neurostimulation, and behavioral approaches

in Neuropsychology

Sarfaraz K. Niazi

Frontiers in Psychology

doi 10.3389/fpsyg.2026.1762816

294 views

Original Research

Published on 04 Mar 2026

Association of Stanford, DeBakey classification and false-lumen blood flow with age of onset in acute aortic dissection

in Cardiovascular Surgery

Kentaro Shirakura
Ryohei Ushioda
Shingo Kunioka
Jeonga Lee
Hidenobu Akamatsu
Akito Inoue
Yuki Setogawa
Shogo Takahashi
Daisuke Takeyoshi
Kyohei Oyama

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2026.1762060

200 views

Original Research

Published on 04 Mar 2026

Prussian blue-supported platinum nanoparticles as pH-Universal catalase mimics: enabling robust chemiluminescent immunoassay for VEGF in clinical diagnostics

in Biosensors and Biomolecular Electronics

Ying Yang
Jiyixuan Li
Xiang Hu
Yutao Xiu
Miao Zhang
Chao Wang
Xinlin Liu
Bing Liang
Dongming Xing
Tingting Zhang

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2026.1762884

Review

Published on 04 Mar 2026

The lipid–podocyte axis: emerging clues in membranous nephropathy pathogenesis

in Nephrology

Sichao Ma
Mingxin Chang
Dongmei Zhang
Yinping Wang
Shoulin Zhang
Hong’an Wang
Yunfan Liu

Frontiers in Medicine

doi 10.3389/fmed.2026.1722758

181 views

Original Research

Published on 04 Mar 2026

Machine learning tools-based diagnosis of soil nutrient constraints to increase the productivity of citrus orchards

in Climate-Smart Agronomy

Heiplanmi Rymbai
Leon-Etienne Parent
Anoop Kumar Srivastava
Hammylliende Talang
Veerendra Kumar Verma
Vasileios Ziogas
Joiedevivreson Mawlein
Thangavel Ramesh
Samarendra Hazarika
Lohit Kumar Baishya

Frontiers in Agronomy

doi 10.3389/fagro.2026.1719690

268 views

Original Research

Published on 04 Mar 2026

InfoMSD: an information-maximization self-distillation framework for parameter-efficient fine-tuning on artwork images

in Pattern Recognition

Feng Guan
Hao Hong
Yong Wang

Frontiers in Artificial Intelligence

doi 10.3389/frai.2026.1721866

162 views

Original Research

Published on 04 Mar 2026

Alcohol craving and levels of suppression of depression, anxiety and anger in patients before and after alcohol dependence treatment in the form of a day ward

in Addictive Disorders

Marta Giezek
Aleksandra Szylińska
Paulina Zabielska
Beata Karakiewicz

Frontiers in Psychiatry

doi 10.3389/fpsyt.2026.1722260

Hypothesis and Theory

Published on 04 Mar 2026

Integrating neural organoids and AI: increasing the risk of artificial consciousness or medical malpractice?

in Methods and Model Organisms

Alexander R. Harris
Patrick McGivern
Kyle C. A. Wedgwood
Frederic Gilbert

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2026.1767365

211 views

Editorial

Published on 04 Mar 2026

Editorial: Global suffering and uncertainty in the COVID-19 pandemic: exposing the fault lines through narrative/discourse analysis

in Health Communication

Shamshad Khan
Kimberly N. Kline
Annette J. Browne
Sheryl Reimer-Kirkham

Frontiers in Communication

doi 10.3389/fcomm.2026.1765039

137 views

Original Research

Published on 04 Mar 2026

Distribution characteristics and influencing factors of carbon storage in Populus plantations with different stand ages in the Luxi Yellow River floodplain, China

in Functional Plant Ecology

Zhibao Wang
Xuehui Sun
Yuwei Guo
Chuanjie Zhou
Jing Liang
Haibing Wu
Cheng Huang
Xiangbin Gao
Yanyi Zhang

Frontiers in Plant Science

doi 10.3389/fpls.2026.1764796

149 views

Original Research

Published on 04 Mar 2026

Dual-functional sulfonated PEEK implants via graphene oxide–mediated BMP-2 gene delivery: enhanced osteogenic and antibacterial performance in vitro

in Translational Medicine

Yueying Pan
Bumairemu Yiminjiang
Adilai Abula
Refeina Tuerxun
Maihefuzi Aishan

Frontiers in Medicine

doi 10.3389/fmed.2026.1763692

Original Research

Published on 04 Mar 2026

Femoral fracture leads to moderate pulmonary organ damage in aged mice and induces immune alterations

in Inflammation

Jasmin Maria Bülow
Helen Rinderknecht
Alessa Wagner
Melanie Haffner-Luntzer
Katrin Bundkirchen
Claudia Neunaber
Borna Relja
Nils Becker

Frontiers in Immunology

doi 10.3389/fimmu.2026.1763857

Review

Published on 04 Mar 2026

Immune effector cell-associated neurotoxicity syndrome: integrative mechanisms, predictive biomarkers, and translational pathways for prevention in CAR T-cell therapy

in Experimental Therapeutics

Faisal Aziz
Abhijit Chakraborty
Dwaipayan Saha
Preyangsee Dutta

Frontiers in Neurology

doi 10.3389/fneur.2026.1739021

240 views

Original Research

Published on 04 Mar 2026

Acute effects of strength training interventions on subjective, neuromuscular, and biochemical fatigue parameters in elite youth soccer players

in Elite Sports and Performance Enhancement

Björn Kadlubowski
Michael Keiner
Klaus Wirth
Robert Csapo

Frontiers in Sports and Active Living

doi 10.3389/fspor.2026.1742295

Hypothesis and Theory

Published on 04 Mar 2026

From touch to triage: translating the NAME model into clinical practice for enhanced neonatal assessment

in Neonatology

Francesco Cerritelli
Caterina Accardi
Alessia Alati
Adele Alberti
Marco Chiera
Matteo Galli
Chiara Leva
Erica Lombardi
Micol Pivotto
Sonia Travaglini

Frontiers in Pediatrics

doi 10.3389/fped.2026.1734450

222 views

Articles

Uncovering the mechanism of arecoline’s effect on oral submucous fibrosis: integrating transcriptomics and in vitro and in vivo experiments

Therapeutic modulation of empathy: pharmacological, neurostimulation, and behavioral approaches

Association of Stanford, DeBakey classification and false-lumen blood flow with age of onset in acute aortic dissection

Prussian blue-supported platinum nanoparticles as pH-Universal catalase mimics: enabling robust chemiluminescent immunoassay for VEGF in clinical diagnostics

The lipid–podocyte axis: emerging clues in membranous nephropathy pathogenesis

Machine learning tools-based diagnosis of soil nutrient constraints to increase the productivity of citrus orchards

InfoMSD: an information-maximization self-distillation framework for parameter-efficient fine-tuning on artwork images

Alcohol craving and levels of suppression of depression, anxiety and anger in patients before and after alcohol dependence treatment in the form of a day ward

Integrating neural organoids and AI: increasing the risk of artificial consciousness or medical malpractice?

Editorial: Global suffering and uncertainty in the COVID-19 pandemic: exposing the fault lines through narrative/discourse analysis

Distribution characteristics and influencing factors of carbon storage in Populus plantations with different stand ages in the Luxi Yellow River floodplain, China

Dual-functional sulfonated PEEK implants via graphene oxide–mediated BMP-2 gene delivery: enhanced osteogenic and antibacterial performance in vitro

Femoral fracture leads to moderate pulmonary organ damage in aged mice and induces immune alterations

Immune effector cell-associated neurotoxicity syndrome: integrative mechanisms, predictive biomarkers, and translational pathways for prevention in CAR T-cell therapy

Acute effects of strength training interventions on subjective, neuromuscular, and biochemical fatigue parameters in elite youth soccer players

From touch to triage: translating the NAME model into clinical practice for enhanced neonatal assessment