Generalized Linear Mixed Model | List of Frontiers open access articles

Case Report

Published on 18 Dec 2025

Donafenib intolerance in hepatocellular carcinoma: severe hand–foot skin reaction and successful switch to lenvatinib – a case report and literature review

in Pharmacology of Anti-Cancer Drugs

Ying Chen
Linglin Fu
Ping Song
Yinuo Tan
Yuqi Jin

Frontiers in Oncology

doi 10.3389/fonc.2025.1728098

143 views

Case Report

Published on 18 Dec 2025

Case Report: Challenges of an extremely delayed diagnosis of classic congenital adrenal hyperplasia in a completely virilized 46,XX patient

in Pediatric Endocrinology

Alice Casiraghi
Irene Campi
Silvia Federici
Franco Cernigliaro
Soara Menabò
Luca Persani

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1726368

138 views

Original Research

Published on 18 Dec 2025

Emotional intelligence and holistic student development: an assessment of psychological and social efficacy in vocational university English education

in Educational Psychology

Qilin Xuan

Frontiers in Psychology

doi 10.3389/fpsyg.2025.1664645

145 views

Original Research

Published on 18 Dec 2025

Therapeutic trough mycophenolic acid levels positively correlate with omega-3 fatty acids in leukocytes of children with idiopathic nephrotic syndrome. a pilot study

in Renal Pharmacology

Stefano Turolo
Alberto Edefonti
Marie-Louise Syren
Anita S. Bellotti
William Morello
Federica Collino
Carlo Agostoni
Giovanni Montini

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1672304

Original Research

Published on 18 Dec 2025

Impact of inotuzumab ozogamicin as bridging therapy and tumor burden in CAR-T therapy for B-acute lymphoblastic leukemia

in Cancer Immunity and Immunotherapy

Patricia Alcalde-Mellado
Victoria Ruiz-Maldonado
Javier Delgado-Serrano
Luzalba Sanoja-Flores
Marta Reinoso-Segura
Laura Pérez-Ortega
Belén Sierro-Martínez
Estefanía García-Guerrero
Concepción Pérez de Soto
José María Pérez-Hurtado

Frontiers in Immunology

doi 10.3389/fimmu.2025.1725878

149 views

Case Report

Published on 18 Dec 2025

Case Report: UMOD gene mutation and phenotypic overlap with REN in autosomal dominant tubulointerstitial kidney disease

in Genetics of Common and Rare Diseases

Jingying Xu
Enhui Chen
Wen Shi
Wenhui He
Dongrong Yu
Xianfa Li

Frontiers in Genetics

doi 10.3389/fgene.2025.1661377

192 views

Original Research

Published on 18 Dec 2025

Expanding the spectrum of NUS1-related progressive myoclonic epilepsy: a novel variant and exploratory use of metformin

in Genetics of Common and Rare Diseases

Cristina Sau
Sergi López-Rodríguez
Mercè Falip
Anna Esteve-Garcia
Jacint Sala-Padró
Cinthia Aguilera
Alba Navarro-Romero
Amaia Lasa-Aranzasti
Laura Rodríguez-Bel
Guillermo Hernández-Pérez

Frontiers in Genetics

doi 10.3389/fgene.2025.1665623

199 views

Mini Review

Published on 18 Dec 2025

Identification of a set of key aspects for heritage assets investments to support private operators in the decision-making processes

in Sustainable Design and Construction

Felicia Di Liddo
Marco Locurcio
Pierluigi Morano
Laura Tatulli

Frontiers in Built Environment

doi 10.3389/fbuil.2025.1717195

160 views

Opinion

Published on 18 Dec 2025

Application of next-generation sequencing to determine mutations in candidate genes for congenital eye malformations in the Mexican indigenous population

in Genetics of Common and Rare Diseases

Iván Antonio García-Montalvo
Diana Matías-Pérez
María José Ruiz-Sanginéz
Juan Carlos Zenteno

Frontiers in Genetics

doi 10.3389/fgene.2025.1710953

165 views

Original Research

Published on 18 Dec 2025

Post-translational modification gene signatures implicate FBXW7 in immune and vascular dysregulation of Moyamoya disease

in Human and Medical Genomics

Xiaofan Yu
Zicong Wang
Zhenyu Zhou
Yutong Liu
Shihao He
Yuanli Zhao

Frontiers in Genetics

doi 10.3389/fgene.2025.1723233

251 views

Original Research

Published on 18 Dec 2025

Global-scale seasonal variability profiles of EPIC-derived vs. GISS ModelE-simulated all-cloud and ice-cloud fraction distributions

in Multi- and Hyper-Spectral Imaging

Gary L. Russell
Andrew A. Lacis
Barbara E. Carlson
Wenying Su
Juliet A. Pilewskie

Frontiers in Remote Sensing

doi 10.3389/frsen.2025.1691948

147 views

Original Research

Published on 18 Dec 2025

Imports matter more than you think: a complexity-weighted reassessment of trade and GDP growth

in Interdisciplinary Physics

Yutai Zhang
Yihua Zhou
Niuniu Fan
Xinyue Sun
Siqing Pang
Liangli Yang
Jieqi Lei
Ruijie Wu
Yixiu Kong

Frontiers in Physics

doi 10.3389/fphy.2025.1721159

230 views

Original Research

Published on 18 Dec 2025

Challenges in acute management of cerebral sinovenous thrombosis among neonates with acute kidney injury: a retrospective cohort study

in Stroke in the Young

Manish Parakh
Marilyn Tan
Ankit Kumar Meena

Frontiers in Stroke

doi 10.3389/fstro.2025.1692460

146 views

Original Research

Published on 18 Dec 2025

Synergistic therapy for osteoporosis: a soybean osteogenic peptide-loaded fish gelatin/κ-carrageenan gel for enhanced bone regeneration

in Nutrition and Food Science Technology

Jinpeng Gong
Yuhan Zhang
Tao Jie
Tao Huang
Yupeng Ma
Hao Chen
Jing Gan
Junbo Ge

Frontiers in Nutrition

doi 10.3389/fnut.2025.1735717

151 views

Review

Published on 18 Dec 2025

Bridging ancient wisdom and modern technology: an AI and multi-omics framework for three causes tailored treatment in personalized medicine

in Molecular Diagnostics and Therapeutics

Xuewen Diao
Hao Zhang
Shiqi Wang
Qi Zhang
Zulong Wang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1732340

150 views

Original Research

Published on 18 Dec 2025

Predicting isocitrate dehydrogenase status in glioma using hierarchical attention-based deep 3D multiple instance learning

in Cancer Imaging and Image-directed Interventions

Qinqin Xie
Yongheng Sun
Yuxia Liang
Yu Shang
Haifeng Wang
Fan Wang
Rong Wei
Bin Chen
Ming Zhang
Chen Niu

Frontiers in Oncology

doi 10.3389/fonc.2025.1665690

Articles

Donafenib intolerance in hepatocellular carcinoma: severe hand–foot skin reaction and successful switch to lenvatinib – a case report and literature review

Case Report: Challenges of an extremely delayed diagnosis of classic congenital adrenal hyperplasia in a completely virilized 46,XX patient

Emotional intelligence and holistic student development: an assessment of psychological and social efficacy in vocational university English education

Therapeutic trough mycophenolic acid levels positively correlate with omega-3 fatty acids in leukocytes of children with idiopathic nephrotic syndrome. a pilot study

Impact of inotuzumab ozogamicin as bridging therapy and tumor burden in CAR-T therapy for B-acute lymphoblastic leukemia

Case Report: UMOD gene mutation and phenotypic overlap with REN in autosomal dominant tubulointerstitial kidney disease

Expanding the spectrum of NUS1-related progressive myoclonic epilepsy: a novel variant and exploratory use of metformin

Identification of a set of key aspects for heritage assets investments to support private operators in the decision-making processes

Application of next-generation sequencing to determine mutations in candidate genes for congenital eye malformations in the Mexican indigenous population

Post-translational modification gene signatures implicate FBXW7 in immune and vascular dysregulation of Moyamoya disease

Global-scale seasonal variability profiles of EPIC-derived vs. GISS ModelE-simulated all-cloud and ice-cloud fraction distributions

Imports matter more than you think: a complexity-weighted reassessment of trade and GDP growth

Challenges in acute management of cerebral sinovenous thrombosis among neonates with acute kidney injury: a retrospective cohort study

Synergistic therapy for osteoporosis: a soybean osteogenic peptide-loaded fish gelatin/κ-carrageenan gel for enhanced bone regeneration

Bridging ancient wisdom and modern technology: an AI and multi-omics framework for three causes tailored treatment in personalized medicine

Predicting isocitrate dehydrogenase status in glioma using hierarchical attention-based deep 3D multiple instance learning