Genetic Modifiers | List of Frontiers open access articles

Original Research

Published on 03 Oct 2025

Proteomic analysis of nemaline myopathy in infants reveals distinct common dysregulated proteins and cellular pathways

in Neuromuscular Disorders and Peripheral Neuropathies

Carola Hedberg-Oldfors
Ali Zeki Bedir
Kittichate Visuttijai
Eva Michael
Anders Oldfors

Frontiers in Neurology

doi 10.3389/fneur.2025.1661747

314 views

Original Research

Published on 03 Oct 2025

Evaluating the effectiveness of intravenous alteplase in patients with minor non-disabling stroke and severe large vessel stenosis: a retrospective study

in Stroke

Qiong Du
Xiaoxuan Li
Yangli Tang
Xuemei Li
Xijun Li
Haichun Hou
Yang Yan
Xichang Liu
Zhengbiao Huang
Zhenxing Liu

Frontiers in Neurology

doi 10.3389/fneur.2025.1661549

387 views

Original Research

Published on 03 Oct 2025

Empowering college students to select ideal advisors: a text-based recommendation model

in Digital Learning Innovations

Xinmin Wang
Jiaxin Zhou
Ling Jian
Yue Yin
Li Li

Frontiers in Education

doi 10.3389/feduc.2025.1673956

135 views

Original Research

Published on 03 Oct 2025

Outcome of limb lengthening as a treatment for shortening following successful replantation of traumatic leg amputation: experience with 21 patients

in Orthopedic Surgery

Caifeng Wu
Kai Liu
Shengquan Ren
Mingming Liu
Xiaoheng Ding
Aihemaitijiang Yusufu

Frontiers in Surgery

doi 10.3389/fsurg.2025.1686865

165 views

Original Research

Published on 03 Oct 2025

Decoding the regulatory networks of Proteus mirabilis under succinic acid stress: a multi-omics approach

in Molecular Bacterial Pathogenesis

Aoyu Yang
Yuqing Cai
Ziyi Zhang
Yafang Xu
Chen Shen
Wei Wang
Haiqing You
Shanshan Sha
Huajun Li
Xiancheng Li

Frontiers in Cellular and Infection Microbiology

doi 10.3389/fcimb.2025.1650340

608 views

Original Research

Published on 03 Oct 2025

From implementation to discontinuation: multi-year experience with the multiple sclerosis performance test as a digital monitoring tool

in Human Factors and Digital Health

Dirk Schriefer
Anja Dillenseger
Yassin Atta
Hernan Inojosa
Tjalf Ziemssen

Frontiers in Digital Health

doi 10.3389/fdgth.2025.1672732

307 views

Original Research

Published on 03 Oct 2025

Mechanism, contributing factors, and coping strategies of alarm fatigue in intensive care nursing: a qualitative study

in Occupational Health and Safety

Ling Zhu
Siying Wei
Yawen An
Wenjun Hu
Xiaofeng Xie

Frontiers in Public Health

doi 10.3389/fpubh.2025.1654389

123 views

Original Research

Published on 03 Oct 2025

Effects of dietary supplementation with hydroponic wheat seedlings on rumen fermentation, meat quality, amino acid and fatty acid contents, and rumen bacterial diversity in sheep

in Microorganisms in Vertebrate Digestive Systems

Yong Tuo
Jinlong Li
Guzalnur Amat
Zhiqiang Cheng
Liangzhong Hou
Changjiang Zang
Tongjun Guo

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1657777

781 views

Original Research

Published on 03 Oct 2025

Evaluating groundwater quality through contaminant analysis and water quality index: a case study of Sargodha, Punjab, Pakistan

in Water and Wastewater Management

Doaa Sami Khafaga
Asifa Iqbal
Shahid Mahmood
Arfan Shahzad
Marwa M. Eid
Amal Ali Alhussan
El-Sayed M. El-Kenawy

Frontiers in Environmental Science

doi 10.3389/fenvs.2025.1636843

425 views

Original Research

Published on 03 Oct 2025

IoT climate resilience in Central Asia: understanding perceived risks through a user survey analysis applied to Kazakhstan

in Smart Technologies and Cities

Dinara Zhunissova
David Topping
James Evans

Frontiers in Sustainable Cities

doi 10.3389/frsc.2025.1433488

425 views

Case Report

Published on 03 Oct 2025

Case Report: Dual molecular diagnosis of gain-of-function STAT1 mutation and regulatory STAT3 variant in a patient with a hyper-IgE-like phenotype

in Primary Immunodeficiencies

Roukaya Yaakoubi
Najla Mekki
Amel Ben Chehida
Ansem Benhammadi
Koon-Wing Chan
Daniel Leung
Charfeddine Gharsallah
Fatma Zahra Guerfali
Mohamed-Ridha Barbouche
Yu Lung Lau

Frontiers in Immunology

doi 10.3389/fimmu.2025.1646761

1,281 views

Original Research

Published on 03 Oct 2025

Effects of a novel fulvic acid-enriched water-soluble fertilizer on potato growth, yield, and water-fertilizer use efficiency under different drip irrigation regimes

in Crop and Product Physiology

Fulin Xu
Yi Liu
Jiangtao Li
Jinquan Zhu
Nan Wu
Ajing Meng

Frontiers in Plant Science

doi 10.3389/fpls.2025.1672560

1,085 views

Original Research

Published on 03 Oct 2025

Using climbing to quantify motor asymmetry in children with cerebral palsy: a pilot study

in Sports Science, Technology and Engineering

Cecilia Monoli
Greta Simoni
Manuela Galli
Alessandro Colombo

Frontiers in Sports and Active Living

doi 10.3389/fspor.2025.1541106

463 views

Review

Published on 03 Oct 2025

Pesticides, an urgent challenge to global environmental health and planetary boundaries

in Developmental and Reproductive Toxicology

Laura N. Vandenberg
Elise J. Pierce
Rachel M. Arsenault

Frontiers in Toxicology

doi 10.3389/ftox.2025.1656297

276 views

Original Research

Published on 03 Oct 2025

Characterizing chlorotriazine effects in cancer-relevant high-throughput screening assays

in In Vitro Toxicology

Agnes L. Karmaus
Alex Charlton

Frontiers in Toxicology

doi 10.3389/ftox.2025.1682439

215 views

Mini Review

Published on 03 Oct 2025

Biocultural and technological diversity of edible wild mushrooms in indigenous communities in Mexico

in Agroecology and Ecosystem Services

Iván Antonio García-Montalvo
Diana Matías-Pérez
Emilio Hernández-Bautista
Alma Dolores Pérez-Santiago
Carlos Francisco Varapizuela-Sánchez
Marco Antonio Sánchez-Medina
Alma Lilia Antonio-Cruz
Andrea Monserrat Leyva-Luna

Frontiers in Sustainable Food Systems

doi 10.3389/fsufs.2025.1654103

286 views

Articles

Proteomic analysis of nemaline myopathy in infants reveals distinct common dysregulated proteins and cellular pathways

Evaluating the effectiveness of intravenous alteplase in patients with minor non-disabling stroke and severe large vessel stenosis: a retrospective study

Empowering college students to select ideal advisors: a text-based recommendation model

Outcome of limb lengthening as a treatment for shortening following successful replantation of traumatic leg amputation: experience with 21 patients

Decoding the regulatory networks of Proteus mirabilis under succinic acid stress: a multi-omics approach

From implementation to discontinuation: multi-year experience with the multiple sclerosis performance test as a digital monitoring tool

Mechanism, contributing factors, and coping strategies of alarm fatigue in intensive care nursing: a qualitative study

Effects of dietary supplementation with hydroponic wheat seedlings on rumen fermentation, meat quality, amino acid and fatty acid contents, and rumen bacterial diversity in sheep

Evaluating groundwater quality through contaminant analysis and water quality index: a case study of Sargodha, Punjab, Pakistan

IoT climate resilience in Central Asia: understanding perceived risks through a user survey analysis applied to Kazakhstan

Case Report: Dual molecular diagnosis of gain-of-function STAT1 mutation and regulatory STAT3 variant in a patient with a hyper-IgE-like phenotype

Effects of a novel fulvic acid-enriched water-soluble fertilizer on potato growth, yield, and water-fertilizer use efficiency under different drip irrigation regimes

Using climbing to quantify motor asymmetry in children with cerebral palsy: a pilot study

Pesticides, an urgent challenge to global environmental health and planetary boundaries

Characterizing chlorotriazine effects in cancer-relevant high-throughput screening assays

Biocultural and technological diversity of edible wild mushrooms in indigenous communities in Mexico