Germ Free Gf | List of Frontiers open access articles

Original Research

Published on 07 Jan 2026

Dietary antigens drive the generation of functional cytotoxic intraepithelial lymphocytes for early defense against foodborne pathogens

in Mucosal Immunity

Jisun Jung
Jaeu Yi
Kwang Soon Kim
Charles D. Surh

Frontiers in Immunology

doi 10.3389/fimmu.2025.1639120

1,157 views

Original Research

Published on 22 Dec 2022

Gut microbiota contributes to the methionine metabolism in host

in Microorganisms in Vertebrate Digestive Systems

Xiaoyan Wu
Ziyi Han
Bingnan Liu
Dongming Yu
Jing Sun
Liangpeng Ge
Wenjie Tang
Shaojuan Liu

Frontiers in Microbiology

doi 10.3389/fmicb.2022.1065668

7,489 views
39 citations

Original Research

Published on 20 Dec 2024

Lactiplantibacillusplantarum HM-P2 influences gestational gut microbiome and microbial metabolism

in Nutrition and Metabolism

Bin Liu
Zhenzhen Zhang
Junying Zhao
Xianping Li
Yaru Wang
Lu Liu
Weicang Qiao
Lijun Chen

Frontiers in Nutrition

doi 10.3389/fnut.2024.1489359

2,713 views

Brief Research Report

Published on 02 Oct 2020

Gut Microbiome Alters the Activity of Liver Cytochromes P450 in Mice With Sex-Dependent Differences

in Gastrointestinal and Hepatic Pharmacology

Lenka Jourová
Marketa Vavreckova
Nina Zemanova
Pavel Anzenbacher
Katerina Langova
Petra Hermanova
Tomas Hudcovic
Eva Anzenbacherova

Frontiers in Pharmacology

doi 10.3389/fphar.2020.01303

6,017 views
23 citations

Review

Published on 02 Jun 2022

The Function and the Affecting Factors of the Zebrafish Gut Microbiota

in Microorganisms in Vertebrate Digestive Systems

Pingping Li
Jinhua Zhang
Xiaoyi Liu
Lu Gan
Yi Xie
Hong Zhang
Jing Si

Frontiers in Microbiology

doi 10.3389/fmicb.2022.903471

9,520 views
41 citations

Original Research

Published on 05 Jan 2022

Intestinal Microbiota and Serum Metabolic Profile Responded to Two Nutritional Different Diets in Mice

in Nutrition and Microbes

Zhifeng Wu
Wei Cheng
Zhenyu Wang
Shuaifei Feng
Huicong Zou
Xiang Tan
Yapeng Yang
Yuqing Wang
Hang Zhang
Miaomiao Dong

Frontiers in Nutrition

doi 10.3389/fnut.2021.813757

5,747 views
15 citations

Methods

Published on 27 Dec 2016

Generation of Germ-Free Ciona intestinalis for Studies of Gut-Microbe Interactions

in Microbial Symbioses

Brittany A. Leigh
Assunta Liberti
Larry J. Dishaw

Frontiers in Microbiology

doi 10.3389/fmicb.2016.02092

5,750 views
24 citations

Original Research

Published on 29 May 2019

The Promoting Effect of Gut Microbiota on Growth and Development of Red Palm Weevil, Rhynchophorus ferrugineus (Olivier) (Coleoptera: Dryophthoridae) by Modulating Its Nutritional Metabolism

in Microbial Symbioses

Prosper Habineza
Abrar Muhammad
Tianliang Ji
Rong Xiao
Xianyuan Yin
Youming Hou
Zhanghong Shi

Frontiers in Microbiology

doi 10.3389/fmicb.2019.01212

8,191 views
65 citations

Original Research

Published on 23 Apr 2013

Cerebral Low-Molecular Metabolites Influenced by Intestinal Microbiota: A Pilot Study

Mitsuharu Matsumoto
Ryoko Kibe
Takushi Ooga
Yuji Aiba
Emiko Sawaki
Yasuhiro Koga
Yoshimi Benno

Frontiers in Systems Neuroscience

doi 10.3389/fnsys.2013.00009

27,531 views
212 citations

Original Research

Published on 03 May 2021

Listeria monocytogenes Establishes Commensalism in Germ-Free Mice Through the Reversible Downregulation of Virulence Gene Expression

in Mucosal Immunity

Kyungjin Cho
Darina Spasova
Sung-Wook Hong
Eunju O
Charles D. Surh
Sin-Hyeog Im
Kwang Soon Kim

Frontiers in Immunology

doi 10.3389/fimmu.2021.666088

6,347 views
10 citations

Original Research

Published on 13 Feb 2020

Microbial Regulation of Enteric Eosinophils and Its Impact on Tissue Remodeling and Th2 Immunity

in Mucosal Immunity

Rodrigo Jiménez-Saiz
Varun C. Anipindi
Heather Galipeau
Yosef Ellenbogen
Roopali Chaudhary
Joshua F. Koenig
Melissa E. Gordon
Tina D. Walker
Talveer S. Mandur
Soumeya Abed

Frontiers in Immunology

doi 10.3389/fimmu.2020.00155

12,462 views
53 citations

Original Research

Published on 07 Feb 2025

Commensal bacteria education history calibrates the naivety and activation threshold of adaptive antiviral immune system

in T Cell Biology

Baohua Li
Zhou Sha
Li Mou
Feng Zhang
Lifeng Jia
Yan Zhu
Yan Guo
Guohong Deng
Haibo Wu
Hong Wei

Frontiers in Immunology

doi 10.3389/fimmu.2025.1519023

3,039 views

Original Research

Published on 14 Jan 2019

Comparative Evaluation of Microbiota Engraftment Following Fecal Microbiota Transfer in Mice Models: Age, Kinetic and Microbial Status Matter

in Microbial Symbioses

Tiphaine Le Roy
Jean Debédat
Florian Marquet
Carla Da-Cunha
Farid Ichou
Michèle Guerre-Millo
Nathalie Kapel
Judith Aron-Wisnewsky
Karine Clément

Frontiers in Microbiology

doi 10.3389/fmicb.2018.03289

21,796 views
115 citations

Original Research

Published on 20 May 2021

Melatonin Regulates the Neurotransmitter Secretion Disorder Induced by Caffeine Through the Microbiota-Gut-Brain Axis in Zebrafish (Danio rerio)

in Molecular and Cellular Pathology

Zeng Zhang
Qiannan Peng
Dongxue Huo
Shuaiming Jiang
Chenchen Ma
Haibo Chang
Kaining Chen
Congfa Li
Yonggui Pan
Jiachao Zhang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2021.678190

16,341 views
46 citations

Original Research

Published on 23 Aug 2018

Spontaneous Proliferation of CD4+ T Cells in RAG-Deficient Hosts Promotes Antigen-Independent but IL-2-Dependent Strong Proliferative Response of Naïve CD8+ T Cells

in T Cell Biology

Juhee Kim
Jun Young Lee
Kyungjin Cho
Sung-Wook Hong
Kwang Soon Kim
Jonathan Sprent
Sin-Hyeog Im
Charles D. Surh
Jae-Ho Cho

Frontiers in Immunology

doi 10.3389/fimmu.2018.01907

10,451 views
11 citations

Original Research

Published on 14 Aug 2018

Exposure to Yeast Shapes the Intestinal Bacterial Community Assembly in Zebrafish Larvae

in Aquatic Microbiology

Prabhugouda Siriyappagouder
Jorge Galindo-Villegas
Jep Lokesh
Victoriano Mulero
Jorge M. O. Fernandes
Viswanath Kiron

Frontiers in Microbiology

doi 10.3389/fmicb.2018.01868

10,386 views
42 citations

Articles

Dietary antigens drive the generation of functional cytotoxic intraepithelial lymphocytes for early defense against foodborne pathogens

Gut microbiota contributes to the methionine metabolism in host

Lactiplantibacillusplantarum HM-P2 influences gestational gut microbiome and microbial metabolism

Gut Microbiome Alters the Activity of Liver Cytochromes P450 in Mice With Sex-Dependent Differences

The Function and the Affecting Factors of the Zebrafish Gut Microbiota

Intestinal Microbiota and Serum Metabolic Profile Responded to Two Nutritional Different Diets in Mice

Generation of Germ-Free Ciona intestinalis for Studies of Gut-Microbe Interactions

The Promoting Effect of Gut Microbiota on Growth and Development of Red Palm Weevil, Rhynchophorus ferrugineus (Olivier) (Coleoptera: Dryophthoridae) by Modulating Its Nutritional Metabolism

Cerebral Low-Molecular Metabolites Influenced by Intestinal Microbiota: A Pilot Study

Listeria monocytogenes Establishes Commensalism in Germ-Free Mice Through the Reversible Downregulation of Virulence Gene Expression

Microbial Regulation of Enteric Eosinophils and Its Impact on Tissue Remodeling and Th2 Immunity

Commensal bacteria education history calibrates the naivety and activation threshold of adaptive antiviral immune system

Comparative Evaluation of Microbiota Engraftment Following Fecal Microbiota Transfer in Mice Models: Age, Kinetic and Microbial Status Matter

Melatonin Regulates the Neurotransmitter Secretion Disorder Induced by Caffeine Through the Microbiota-Gut-Brain Axis in Zebrafish (Danio rerio)

Spontaneous Proliferation of CD4+ T Cells in RAG-Deficient Hosts Promotes Antigen-Independent but IL-2-Dependent Strong Proliferative Response of Naïve CD8+ T Cells

Exposure to Yeast Shapes the Intestinal Bacterial Community Assembly in Zebrafish Larvae