Hdac3 Inhibition | List of Frontiers open access articles

Original Research

Published on 10 Dec 2020

A Class I Histone Deacetylase Inhibitor Attenuates Insulin Resistance and Inflammation in Palmitate-Treated C2C12 Myotubes and Muscle of HF/HFr Diet Mice

in Experimental Pharmacology and Drug Discovery

Soo Jin Lee
Sung-E Choi
Han Byeol Lee
Min-Woo Song
Young Ha Kim
Jae Yeop Jeong
Yup Kang
Hae Jin Kim
Tae Ho Kim
Ja Young Jeon

Frontiers in Pharmacology

doi 10.3389/fphar.2020.601448

8,171 views
23 citations

Original Research

Published on 25 Apr 2025

HDAC3 inhibition mitigates acute kidney injury by alleviating RIPK1-mediated programmed necrosis

in Renal Pharmacology

Manman Xie
Rui Hou
Runrun Shan
Xinyu Cheng
Pengcheng Wu
Xiufeng Luo
Yangyang Wei
Li Gao
Xiaoying Liu
Qi Chen

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1546950

3,043 views
3 citations

Original Research

Published on 26 Jun 2024

Pharmacological HDAC3 inhibition alters memory updating in young and old male mice

in Molecular Signalling and Pathways

Chad W. Smies
Lauren Bellfy
Destiny S. Wright
Sofia G. Bennetts
Mark W. Urban
Chad A. Brunswick
Guanhua Shu
Janine L. Kwapis

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1429880

4,877 views
5 citations

Review

Published on 10 Jul 2024

The role of HDAC3 in inflammation: mechanisms and therapeutic implications

in Inflammation

Noah Watson
Sivaraman Kuppuswamy
William Luke Ledford
Sangeetha Sukumari-Ramesh

Frontiers in Immunology

doi 10.3389/fimmu.2024.1419685

8,006 views
29 citations

Original Research

Published on 04 Feb 2026

HDAC3 inhibition as a therapeutic strategy in T-cell acute lymphoblastic leukemia via the TYK2-STAT1-BCL2 signaling pathway

in Cancer Immunity and Immunotherapy

Zhenyang Gu
Yuchen Liu
Yifan Jiao
Hao Wang
Lili Wang
Ning Le
Xiawei Zhang
Qingyang Liu
Yang Xu
Daihong Liu

Frontiers in Immunology

doi 10.3389/fimmu.2026.1752727

378 views

Original Research

Published on 17 Feb 2021

The Effects of Selective Inhibition of Histone Deacetylase 1 and 3 in Huntington’s Disease Mice

in Brain Disease Mechanisms

Katharina Hecklau
Susanne Mueller
Stefan Paul Koch
Mustafa Hussain Mehkary
Busra Kilic
Christoph Harms
Philipp Boehm-Sturm
Ferah Yildirim

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2021.616886

7,795 views
25 citations

Articles

A Class I Histone Deacetylase Inhibitor Attenuates Insulin Resistance and Inflammation in Palmitate-Treated C2C12 Myotubes and Muscle of HF/HFr Diet Mice

HDAC3 inhibition mitigates acute kidney injury by alleviating RIPK1-mediated programmed necrosis

Pharmacological HDAC3 inhibition alters memory updating in young and old male mice

The role of HDAC3 in inflammation: mechanisms and therapeutic implications

HDAC3 inhibition as a therapeutic strategy in T-cell acute lymphoblastic leukemia via the TYK2-STAT1-BCL2 signaling pathway

The Effects of Selective Inhibition of Histone Deacetylase 1 and 3 in Huntington’s Disease Mice