Her2 Mutations | List of Frontiers open access articles

Original Research

Published on 23 Feb 2022

Associations of HER2 Mutation With Immune-Related Features and Immunotherapy Outcomes in Solid Tumors

in Cancer Immunity and Immunotherapy

Deqiang Wang
Xiaofeng Chen
Yian Du
Xiaoqin Li
Leqian Ying
Yi Lu
Bo Shen
Xuan Gao
Xin Yi
Xuefeng Xia

Frontiers in Immunology

doi 10.3389/fimmu.2022.799988

8,607 views
18 citations

Original Research

Published on 31 Jul 2020

HER2 Exon 20 Insertion Mutations in Lung Adenocarcinoma: Case Series and Response to Pyrotinib

in Cancer Molecular Targets and Therapeutics

Xinyong Zhang
Jialin Lv
Yuhua Wu
Na Qin
Li Ma
Xi Li
Jingying Nong
Hui Zhang
Quan Zhang
Xinjie Yang

Frontiers in Oncology

doi 10.3389/fonc.2020.01162

16,863 views
10 citations

Case Report

Published on 14 Mar 2025

A case report of HER2-positive descending colon cancer with peritoneal metastasis and literature review

in Gastrointestinal Cancers: Colorectal Cancer

Yaochun Lv
Zhengpeng Qian
Dewang Wu
Chengzhang Zhu
Jipeng Zhang
Yeping Ning
Binbin Du

Frontiers in Oncology

doi 10.3389/fonc.2025.1473620

2,514 views

Original Research

Published on 07 May 2021

Efficacy and Resistance of Afatinib in Chinese Non-Small Cell Lung Cancer Patients With HER2 Alterations: A Multicenter Retrospective Study

in Thoracic Oncology

Zhengbo Song
Dongqing Lv
Shiqing Chen
Jianhui Huang
Liping Wang
Shuguang Xu
Huafei Chen
Guoqiang Wang
Quan Lin

Frontiers in Oncology

doi 10.3389/fonc.2021.657283

6,300 views
16 citations

Case Report

Published on 28 Oct 2024

Response to furmonertinib in a patient with non-small cell lung cancer harboring HER2 exon 21 insertion mutation: a case report

in Cancer Molecular Targets and Therapeutics

Chunxiao Ni
Ling Zhang
Xin Yu
Yu Pang

Frontiers in Oncology

doi 10.3389/fonc.2024.1440379

2,480 views
2 citations

Original Research

Published on 20 Apr 2021

Efficacy of Combination Chemo-Immunotherapy as a First-Line Treatment for Advanced Non-Small-Cell Lung Cancer Patients With HER2 Alterations: A Case Series

in Thoracic Oncology

Shuang Zhao
Xinghong Xian
Panwen Tian
Weimin Li
Ke Wang
Yalun Li

Frontiers in Oncology

doi 10.3389/fonc.2021.633522

5,881 views
18 citations

Original Research

Published on 25 Feb 2026

Genomic profiling and HER2-targeted therapy: a case series of Chinese salivary duct carcinoma patients and its clinical implications

in Head and Neck Cancer

Xiang Huang
Wei Yu
Xiaomo Li
Boning Cai
Baolin Qu
Jing Chen
Pei Zhang
Xinrui Chen
Yanli Liu
Shengqiang Feng

Frontiers in Oncology

doi 10.3389/fonc.2026.1727362

Review

Published on 20 Jun 2025

HER2 alterations in non-small cell lung cancer (NSCLC): from biology and testing to advances in treatment modalities

in Thoracic Oncology

Ahmed Ismail
Aakash Desai
Yanis Boumber

Frontiers in Oncology

doi 10.3389/fonc.2025.1624124

13,784 views
7 citations

Original Research

Published on 03 Apr 2023

Genomic landscape and efficacy of HER2-targeted therapy in patients with HER2-mutant non-small cell lung cancer

in Cancer Molecular Targets and Therapeutics

Yanjie Han
Yuanyuan Xiong
Tao Lu
Rongrong Chen
Yuan Liu
Hui Tang
Ruixuan Geng
Yingyi Wang

Frontiers in Oncology

doi 10.3389/fonc.2023.1121708

6,345 views
6 citations

Case Report

Published on 18 Jan 2024

Positive response to trastuzumab deruxtecan in a patient with HER2-mutant NSCLC after multiple lines therapy, including T-DM1: a case report

in Thoracic Oncology

Junzhu Xu
Bo He
Yunan Wang
Mengjia Wu
Yanyi Lu
Zixuan Su
Shujun Liu
Fengmin Yin
Jian-Guo Zhou
Wei Hu

Frontiers in Oncology

doi 10.3389/fonc.2023.1268260

4,792 views
7 citations

Original Research

Published on 06 Nov 2024

Efficacy of disitamab vedotin in non-small cell lung cancer with HER2 alterations: a multicenter, retrospective real-world study

in Cancer Molecular Targets and Therapeutics

Meiling Zhang
Li Wang
Qian Wang
Jiu Yang
Wei Peng
Xiaoyou Li
Meiqi Shi
Kaihua Lu

Frontiers in Oncology

doi 10.3389/fonc.2024.1441025

3,758 views
3 citations

Articles

Associations of HER2 Mutation With Immune-Related Features and Immunotherapy Outcomes in Solid Tumors

HER2 Exon 20 Insertion Mutations in Lung Adenocarcinoma: Case Series and Response to Pyrotinib

A case report of HER2-positive descending colon cancer with peritoneal metastasis and literature review

Efficacy and Resistance of Afatinib in Chinese Non-Small Cell Lung Cancer Patients With HER2 Alterations: A Multicenter Retrospective Study

Response to furmonertinib in a patient with non-small cell lung cancer harboring HER2 exon 21 insertion mutation: a case report

Efficacy of Combination Chemo-Immunotherapy as a First-Line Treatment for Advanced Non-Small-Cell Lung Cancer Patients With HER2 Alterations: A Case Series

Genomic profiling and HER2-targeted therapy: a case series of Chinese salivary duct carcinoma patients and its clinical implications

HER2 alterations in non-small cell lung cancer (NSCLC): from biology and testing to advances in treatment modalities

Genomic landscape and efficacy of HER2-targeted therapy in patients with HER2-mutant non-small cell lung cancer

Positive response to trastuzumab deruxtecan in a patient with HER2-mutant NSCLC after multiple lines therapy, including T-DM1: a case report

Efficacy of disitamab vedotin in non-small cell lung cancer with HER2 alterations: a multicenter, retrospective real-world study