Herg1 | List of Frontiers open access articles

Original Research

Published on 23 Feb 2023

Binding of RPR260243 at the intracellular side of the hERG1 channel pore domain slows closure of the helix bundle crossing gate

in Structural Biology

Eva-Maria Zangerl-Plessl
Wei Wu
Michael C. Sanguinetti
Anna Stary-Weinzinger

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1137368

2,757 views
2 citations

Original Research

Published on 24 Apr 2020

hERG K+ Channels Promote Survival of Irradiated Leukemia Cells

in Pharmacology of Ion Channels and Channelopathies

Daniela Palme
Milan Misovic
Katrin Ganser
Lukas Klumpp
Helmut R. Salih
Daniel Zips
Stephan M. Huber

Frontiers in Pharmacology

doi 10.3389/fphar.2020.00489

3,942 views
10 citations

Original Research

Published on 30 Jun 2020

Allosteric Coupling Between Drug Binding and the Aromatic Cassette in the Pore Domain of the hERG1 Channel: Implications for a State-Dependent Blockade

in Pharmacology of Ion Channels and Channelopathies

Meruyert Kudaibergenova
Jiqing Guo
Hanif M. Khan
Farhan Zahid
James Lees-Miller
Sergei Yu. Noskov
Henry J. Duff

Frontiers in Pharmacology

doi 10.3389/fphar.2020.00914

4,197 views
9 citations

Review

Published on 22 Nov 2010

Stereoselective Inhibition of the hERG1 Potassium Channel

in Pharmacology of Ion Channels and Channelopathies

Liliana Sintra Grilo
Pierre-Alain Carrupt
Hugues Abriel

Frontiers in Pharmacology

doi 10.3389/fphar.2010.00137

34,930 views
38 citations

Original Research

Published on 12 Sep 2023

Cardiac safety assessment of a novel recombinant bispecific antibody targeting the ether-à-go-go related gene 1 (hERG1)-β1 integrin macromolecular complex

in Pharmacology of Ion Channels and Channelopathies

Lorenzo Santini
Claudia Duranti
Chiara Palandri
Lucrezia Giammarino
Monica Musumeci
Lucia Carlucci
Chiara Capitani
Rossella Colasurdo
Fabio Recchia
Elisabetta Cerbai

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1237431

3,126 views
5 citations

Original Research

Published on 12 Apr 2018

Determinants of Isoform-Specific Gating Kinetics of hERG1 Channel: Combined Experimental and Simulation Study

in Cardiac Electrophysiology

Laura L. Perissinotti
Pablo M. De Biase
Jiqing Guo
Pei-Chi Yang
Miranda C. Lee
Colleen E. Clancy
Henry J. Duff
Sergei Y. Noskov

Frontiers in Physiology

doi 10.3389/fphys.2018.00207

7,782 views
29 citations

Articles

Binding of RPR260243 at the intracellular side of the hERG1 channel pore domain slows closure of the helix bundle crossing gate

hERG K+ Channels Promote Survival of Irradiated Leukemia Cells

Allosteric Coupling Between Drug Binding and the Aromatic Cassette in the Pore Domain of the hERG1 Channel: Implications for a State-Dependent Blockade

Stereoselective Inhibition of the hERG1 Potassium Channel

Cardiac safety assessment of a novel recombinant bispecific antibody targeting the ether-à-go-go related gene 1 (hERG1)-β1 integrin macromolecular complex

Determinants of Isoform-Specific Gating Kinetics of hERG1 Channel: Combined Experimental and Simulation Study