High Difficulty | List of Frontiers open access articles

Clinical Trial

Accepted on 02 Mar 2026

Effects of remimazolam and sevoflurane on postoperative delirium and early cognitive impairment in elderly patients after laparoscopic assisted gastrointestinal surgery: a randomized clinical trial study

in Intensive Care Medicine and Anesthesiology

Wei Ren
Kai Zheng
Jian Song
Li Zhang
Shenqiang Gao

Frontiers in Medicine

Original Research

Accepted on 02 Mar 2026

Effects of different seasons on the outcome of in vitro fertilization and embryo transfer: a retrospective cohort study

in Assisted Reproduction

Run Zhao
LinLin Che
Qianyan Song
Xiaofang Li
Xiao Li

Frontiers in Reproductive Health

Original Research

Accepted on 02 Mar 2026

CHOICE-AYA: Adapting an evidence-based contraceptive counseling intervention for adolescents and young adults experiencing homelessness

in Adolescent Reproductive Health and Well-being

Mariah Brewe
Anna Burns
Nik Schuetz
Taylor Stephens
Emma Francis
Haylie Yost
Stephani Stancil

Frontiers in Reproductive Health

Original Research

Accepted on 02 Mar 2026

Association Between Low-Density Lipoprotein Cholesterol and Frailty in Adults Aged ≥70 Years: A Cross-Sectional Study from Beijing, China

in Cardiovascular Endocrinology

Wenjing Liu
Yuelin Yu
Shanshan Chen
Xin Ren
Yuting Kang
Xiaojuan Zhou

Frontiers in Endocrinology

Original Research

Accepted on 02 Mar 2026

Digital Twin Virtual Hospitals and Rural Health Disparities: A Six-Country Comparative Study (2018-2024)

in Digital Public Health

Hualei Wang
Xiuhua Chai
Nan Zhao

Frontiers in Public Health

Original Research

Accepted on 02 Mar 2026

UVB-Induced Genotoxic Stress Activates the DNA Damage Response and Innate Immune Pathways in Sea Urchin Coelomocytes

in Comparative Immunology

Riss M Kell
Margaret K Weber
Rosa Y Escalante
Jeffrey C Silva
Andrea G Bodnar

Frontiers in Immunology

Case Report

Accepted on 02 Mar 2026

Gallbladder perforation after endoscopic retrograde cholangiopancreatography: A rare complication

in Hepatobiliary Diseases

Ze-Ming Chen
Jing-Wen Xu
Jin-Feng Wu
Qin-Hua Yang
Wei-Feng Li
Xiqiu Yu

Frontiers in Medicine

Review

Accepted on 02 Mar 2026

Chondrocytes versus Chondroprogenitors for Auricular Cartilage Repair: A Critical Comparative Review

in Stem Cell Research

Ai Jiang
Wenkang Luan
Leren He

Frontiers in Cell and Developmental Biology

Systematic Review

Accepted on 02 Mar 2026

Comparative Effectiveness and Outcomes of Physiology-and Imaging-Guided PCI: An Evidence Synthesis and Network Meta-Analysis of FFR, iFR, OCT, and IVUS

in Coronary Artery Disease

Yuancheng Jin
Wei Wang
Heng Gan
Bin He
Heyong Liu
Xin Gan
Lin Hong
Harshawardhan Dhanraj Ramteke
Liping Luo
Zhicheng Huang

Frontiers in Cardiovascular Medicine

Case Report

Accepted on 02 Mar 2026

Clinical Characteristics of Leukemic Optic Nerve Infiltration in Pediatric Acute Lymphoblastic Leukemia: 3 Cases and A Literature Review

in Ophthalmology

Yiwen Li
Guohong Tian
Aishwarya Sriram
Ling Qin
Quangang Xu
Fang Lei
Cheng Zhang

Frontiers in Medicine

Original Research

Accepted on 02 Mar 2026

Single-center experience description of surgical management of diffuse congenital hyperinsulinism in a pediatric non-current cohort

in Pediatric Endocrinology

Xiaoxiang Li
Congli Chen
Yangmingyue Ji
Yuxi Wang
Yanmei Sang

Frontiers in Endocrinology

Original Research

Accepted on 02 Mar 2026

The Effect of Digital Video Feedback on Roundoff Learning Outcomes in Gymnastics Learning

in Physical Education and Pedagogy

Rizal Ahmad Fauzi
Ayi Suherman
Entan Saptani
Suthana Tingsabhat
Mamat Heryanto

Frontiers in Sports and Active Living

Case Report

Accepted on 02 Mar 2026

Thymoma-associated stiff person syndrome and myasthenia gravis: an index case with exploratory exome sequencing and review of reported cases

in Thoracic Oncology

Min Qiang
Lu Zhao
Linan Fang
Wei Liu

Frontiers in Oncology

Original Research

Accepted on 02 Mar 2026

Seasonal Changes in Lipid Profiles and Homocysteine in Patients With and Without Coronary Heart Disease: A Real-World Paired Retrospective Study in a Cold-Climate Region

in Lipids in Cardiovascular Disease

Tao Liu
Lin Xia
Yingjie Zhang
Entao Zhou
Huishan Wang

Frontiers in Cardiovascular Medicine

Original Research

Accepted on 02 Mar 2026

Soybean oil and leucine in late gestation and lactation improve maternal and offspring lipid metabolism and insulin sensitivity: Insights from pig model

in Animal Nutrition and Metabolism

Yutong Sun
Zexuan Gan
Xueyuan Li
Yuxin Lin
Xinbo Zhou
Qingquan Ma

Frontiers in Veterinary Science

Original Research

Accepted on 02 Mar 2026

Enhancing the Knowledge and Understanding Domain of Physical Literacy: Instrument Validation and a Kahoot-Supported Intervention in Physical Education

in Physical Education and Pedagogy

Bogdan Sorin Olaru
Iconomescu Teodora Mihaela
Laurentiu-Gabriel Talaghir

Frontiers in Sports and Active Living

Articles

Effects of remimazolam and sevoflurane on postoperative delirium and early cognitive impairment in elderly patients after laparoscopic assisted gastrointestinal surgery: a randomized clinical trial study

Effects of different seasons on the outcome of in vitro fertilization and embryo transfer: a retrospective cohort study

CHOICE-AYA: Adapting an evidence-based contraceptive counseling intervention for adolescents and young adults experiencing homelessness

Association Between Low-Density Lipoprotein Cholesterol and Frailty in Adults Aged ≥70 Years: A Cross-Sectional Study from Beijing, China

Digital Twin Virtual Hospitals and Rural Health Disparities: A Six-Country Comparative Study (2018-2024)

UVB-Induced Genotoxic Stress Activates the DNA Damage Response and Innate Immune Pathways in Sea Urchin Coelomocytes

Gallbladder perforation after endoscopic retrograde cholangiopancreatography: A rare complication

Chondrocytes versus Chondroprogenitors for Auricular Cartilage Repair: A Critical Comparative Review

Comparative Effectiveness and Outcomes of Physiology-and Imaging-Guided PCI: An Evidence Synthesis and Network Meta-Analysis of FFR, iFR, OCT, and IVUS

Clinical Characteristics of Leukemic Optic Nerve Infiltration in Pediatric Acute Lymphoblastic Leukemia: 3 Cases and A Literature Review

Single-center experience description of surgical management of diffuse congenital hyperinsulinism in a pediatric non-current cohort

The Effect of Digital Video Feedback on Roundoff Learning Outcomes in Gymnastics Learning

Thymoma-associated stiff person syndrome and myasthenia gravis: an index case with exploratory exome sequencing and review of reported cases

Seasonal Changes in Lipid Profiles and Homocysteine in Patients With and Without Coronary Heart Disease: A Real-World Paired Retrospective Study in a Cold-Climate Region

Soybean oil and leucine in late gestation and lactation improve maternal and offspring lipid metabolism and insulin sensitivity: Insights from pig model

Enhancing the Knowledge and Understanding Domain of Physical Literacy: Instrument Validation and a Kahoot-Supported Intervention in Physical Education