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3 articles related to "Hpk1"

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Articles

Original Research

Published on 06 Feb 2025

HPK1 kinase inhibitor: a sufficient approach to target HPK1 to modulate T cell activation in cancer immunotherapy compared with degraders

in Cancer Immunity and Immunotherapy

Qin Wang
Xinyi Zhu
Jing Li
Sanjia Xu
Ali Wang
Xinwen Zhang
Xingxing Wang
Xiaopeng Cai
Haimei Xing
Ye Liu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1449106

7,858 views
4 citations

Original Research

Published on 14 Mar 2022

Discovery of Novel HPK1 Inhibitors Through Structure-Based Virtual Screening

in Experimental Pharmacology and Drug Discovery

Huizhen Ge
Lizeng Peng
Zhou Sun
Huanxiang Liu
Yulin Shen
Xiaojun Yao

Frontiers in Pharmacology

doi 10.3389/fphar.2022.850855

15,019 views
15 citations

Review

Published on 25 Jul 2019

Bridging the Gap: Modulatory Roles of the Grb2-Family Adaptor, Gads, in Cellular and Allergic Immune Responses

in T Cell Biology

Deborah Yablonski

Frontiers in Immunology

doi 10.3389/fimmu.2019.01704

12,524 views
44 citations