Human Clinical Trials | List of Frontiers open access articles

Original Research

Published on 06 Apr 2023

H3N2 influenza hemagglutination inhibition method qualification with data driven statistical methods for human clinical trials

in Vaccines and Molecular Therapeutics

Sheetal Sawant
Sarah Anne Gurley
R. Glenn Overman
Angelina Sharak
Sarah V. Mudrak
Thomas Oguin
Gregory D. Sempowski
Marcella Sarzotti-Kelsoe
Emmanuel B. Walter
Hang Xie

Frontiers in Immunology

doi 10.3389/fimmu.2023.1155880

12,099 views
7 citations

Review

Published on 05 Aug 2021

Pain Treatment in the Companion Canine Model to Validate Rodent Results and Incentivize the Transition to Human Clinical Trials

in Translational Pharmacology

Michael J. Iadarola
Dorothy Cimino Brown
Alexis Nahama
Matthew R. Sapio
Andrew J. Mannes

Frontiers in Pharmacology

doi 10.3389/fphar.2021.705743

8,636 views
20 citations

Review

Published on 21 Oct 2024

Clinical applications and therapeutic potentials of advanced nanoparticles: a comprehensive review on completed human clinical trials

in Nanomaterials

Ranil Vikraman Kumarasamy
Prabhu Manickam Natarajan
Vidhya Rekha Umapathy
Jeane Rebecca Roy
Monica Mironescu
Chella Perumal Palanisamy

Frontiers in Nanotechnology

doi 10.3389/fnano.2024.1479993

20,718 views
86 citations

Mini Review

Published on 12 Aug 2022

Using the canine microbiome to bridge translation of cancer immunotherapy from pre-clinical murine models to human clinical trials

in Cancer Immunity and Immunotherapy

Kara T. Kleber
Khurshid R. Iranpur
Lauren M. Perry
Sylvia M. Cruz
Aryana M. Razmara
William T. N. Culp
Michael S. Kent
Jonathan A. Eisen
Robert B. Rebhun
Robert J. Canter

Frontiers in Immunology

doi 10.3389/fimmu.2022.983344

9,920 views
17 citations

Case Report

Published on 26 Oct 2022

Case report: MicroRNA-10b as a therapeutic target in feline metastatic mammary carcinoma and its implications for human clinical trials

in Cancer Molecular Targets and Therapeutics

N. Anna Savan
Paulo Vilar Saavedra
Alan Halim
Vilma Yuzbasiyan-Gurkan
Ping Wang
Byunghee Yoo
Matti Kiupel
Lorenzo Sempere
Zdravka Medarova
Anna Moore

Frontiers in Oncology

doi 10.3389/fonc.2022.959630

4,613 views
8 citations

Review

Published on 30 Jun 2023

Effects of probiotics on non-alcoholic fatty liver disease: a review of human clinical trials

in Nutrition and Metabolism

Chujin Cao
Mengxia Shi
Xiuru Wang
Ying Yao
Rui Zeng

Frontiers in Nutrition

doi 10.3389/fnut.2023.1155306

10,599 views
28 citations

Perspective

Published on 30 Nov 2021

Cell Therapy in Veterinary Medicine as a Proof-of-Concept for Human Therapies: Perspectives From the North American Veterinary Regenerative Medicine Association

in Veterinary Regenerative Medicine

Boaz Arzi
Tracy L. Webb
Thomas G. Koch
Susan W. Volk
Dean H. Betts
Ashlee Watts
Laurie Goodrich
Michael S. Kallos
Amir Kol

Frontiers in Veterinary Science

doi 10.3389/fvets.2021.779109

9,706 views
19 citations

Review

Published on 19 May 2020

What Can Gamma Delta T Cells Contribute to an HIV Cure?

in Virus and Host

Jennifer A. Juno
Stephen J. Kent

Frontiers in Cellular and Infection Microbiology

doi 10.3389/fcimb.2020.00233

11,148 views
23 citations

Review

Published on 14 May 2024

The aryl hydrocarbon receptor as a tumor modulator: mechanisms to therapy

in Molecular and Cellular Oncology

Kanita A. Chaudhry
Anna Bianchi-Smiraglia

Frontiers in Oncology

doi 10.3389/fonc.2024.1375905

5,229 views
10 citations

Mini Review

Published on 17 May 2022

Considerations for Choosing Soluble Immune Markers to Determine Safety of Novel Vaginal Products

in Gynecology

Anna-Ursula Happel
Aida Sivro
Lenine Liebenberg
Jo Ann Passmore
Caroline M. Mitchell

Frontiers in Reproductive Health

doi 10.3389/frph.2022.899277

3,293 views
1 citation

Mini Review

Published on 21 Jun 2024

Updates in the skeletal and joint protective effects of tocotrienol: a mini review

in Bone Research

Kok-Yong Chin

Frontiers in Endocrinology

doi 10.3389/fendo.2024.1417191

4,860 views
6 citations

Review

Published on 28 Jun 2016

Intracortical Brain-Machine Interfaces Advance Sensorimotor Neuroscience

in Neuroprosthetics

Karen E. Schroeder
Cynthia A. Chestek

Frontiers in Neuroscience

doi 10.3389/fnins.2016.00291

7,816 views
27 citations

Review

Published on 07 Jul 2021

Staphylococcus aureus Vaccine Research and Development: The Past, Present and Future, Including Novel Therapeutic Strategies

in Vaccines and Molecular Therapeutics

Jonah Clegg
Elisabetta Soldaini
Rachel M. McLoughlin
Stephen Rittenhouse
Fabio Bagnoli
Sanjay Phogat

Frontiers in Immunology

doi 10.3389/fimmu.2021.705360

56,638 views
154 citations

Review

Published on 26 Aug 2021

Immunotherapeutic Strategies for Canine Lymphoma: Changing the Odds Against Non-Hodgkin Lymphoma

in Comparative and Clinical Medicine

Joana N. R. Dias
Ana S. André
Sandra I. Aguiar
Solange Gil
Luís Tavares
Frederico Aires-da-Silva

Frontiers in Veterinary Science

doi 10.3389/fvets.2021.621758

21,896 views
16 citations

Perspective

Published on 29 Sep 2017

Monocyte Chemotactic Protein 1 in Plasma from Soluble Leishmania Antigen-Stimulated Whole Blood as a Potential Biomarker of the Cellular Immune Response to Leishmania infantum

in Microbial Immunology

Ana V. Ibarra-Meneses
Carmen Sanchez
Jorge Alvar
Javier Moreno
Eugenia Carrillo

Frontiers in Immunology

doi 10.3389/fimmu.2017.01208

3,056 views
21 citations

Review

Published on 27 Nov 2018

Cartilage Tissue Engineering Using Stem Cells and Bioprinting Technology—Barriers to Clinical Translation

in Orthopedic Surgery

Sam L. Francis
Claudia Di Bella
Gordon G. Wallace
Peter F. M. Choong

Frontiers in Surgery

doi 10.3389/fsurg.2018.00070

24,428 views
92 citations

Articles

H3N2 influenza hemagglutination inhibition method qualification with data driven statistical methods for human clinical trials

Pain Treatment in the Companion Canine Model to Validate Rodent Results and Incentivize the Transition to Human Clinical Trials

Clinical applications and therapeutic potentials of advanced nanoparticles: a comprehensive review on completed human clinical trials

Using the canine microbiome to bridge translation of cancer immunotherapy from pre-clinical murine models to human clinical trials

Case report: MicroRNA-10b as a therapeutic target in feline metastatic mammary carcinoma and its implications for human clinical trials

Effects of probiotics on non-alcoholic fatty liver disease: a review of human clinical trials

Cell Therapy in Veterinary Medicine as a Proof-of-Concept for Human Therapies: Perspectives From the North American Veterinary Regenerative Medicine Association

What Can Gamma Delta T Cells Contribute to an HIV Cure?

The aryl hydrocarbon receptor as a tumor modulator: mechanisms to therapy

Considerations for Choosing Soluble Immune Markers to Determine Safety of Novel Vaginal Products

Updates in the skeletal and joint protective effects of tocotrienol: a mini review

Intracortical Brain-Machine Interfaces Advance Sensorimotor Neuroscience

Staphylococcus aureus Vaccine Research and Development: The Past, Present and Future, Including Novel Therapeutic Strategies

Immunotherapeutic Strategies for Canine Lymphoma: Changing the Odds Against Non-Hodgkin Lymphoma

Monocyte Chemotactic Protein 1 in Plasma from Soluble Leishmania Antigen-Stimulated Whole Blood as a Potential Biomarker of the Cellular Immune Response to Leishmania infantum

Cartilage Tissue Engineering Using Stem Cells and Bioprinting Technology—Barriers to Clinical Translation