Human Liver Microsomes Hlms | List of Frontiers open access articles

Original Research

Published on 04 Feb 2019

Cytochrome P450 3A Enzymes Are Key Contributors for Hepatic Metabolism of Bufotalin, a Natural Constitute in Chinese Medicine Chansu

in Ethnopharmacology

Zi-Ru Dai
Jing Ning
Gui-Bo Sun
Ping Wang
Feng Zhang
Hong-Ying Ma
Li-Wei Zou
Jie Hou
Jing-Jing Wu
Guang-Bo Ge

Frontiers in Pharmacology

doi 10.3389/fphar.2019.00052

5,753 views
21 citations

Original Research

Published on 13 Jun 2019

Metabolism of IMM-H004 and Its Pharmacokinetic-Pharmacodynamic Analysis in Cerebral Ischemia/Reperfusion Injured Rats

in Drug Metabolism and Transport

Ziqian Zhang
Dandan Liu
Jianwei Jiang
Xiuyun Song
Xiaowen Zou
Shifeng Chu
Kebo Xie
Jungui Dai
Naihong Chen
Li Sheng

Frontiers in Pharmacology

doi 10.3389/fphar.2019.00631

4,300 views
4 citations

Original Research

Published on 08 Apr 2024

Effect of P. corylifolia on the pharmacokinetic profile of tofacitinib and the underlying mechanism

in Drug Metabolism and Transport

Yu Wang
Quan Zhou
Huihui Wang
Wei Song
Jianfeng Wang
Abdullah Al Mamun
Peiwu Geng
Yunfang Zhou
Shuanghu Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1351882

2,653 views
2 citations

Original Research

Published on 26 Sep 2018

Atypical Pharmacodynamic Properties and Metabolic Profile of the Abused Synthetic Cannabinoid AB-PINACA: Potential Contribution to Pronounced Adverse Effects Relative to Δ9-THC

in Neuropharmacology

Rachel D. Hutchison
Benjamin M. Ford
Lirit N. Franks
Catheryn D. Wilson
Azure L. Yarbrough
Ryoichi Fujiwara
Mark K. Su
Denise Fernandez
Laura P. James
Jeffery H. Moran

Frontiers in Pharmacology

doi 10.3389/fphar.2018.01084

7,399 views
19 citations

Original Research

Published on 11 Feb 2025

Typical and atypical metabolic characteristics of three iridaceae isoflavone components: in vitro and in silico studies

in Drug Metabolism and Transport

Jifeng Gu
Huishan Zhang
Mei Wang
Yuyang Zhou
Zhipeng Deng
Rong Shi

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1522857

1,952 views
2 citations

Original Research

Published on 18 Sep 2023

Inhibitory mechanism of vortioxetine on CYP450 enzymes in human and rat liver microsomes

in Drug Metabolism and Transport

Yunyun Zhan
Anzhou Wang
Yige Yu
Jie Chen
Xinhao Xu
Jingjing Nie
Jingjing Lin

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1199548

6,126 views
7 citations

Articles

Cytochrome P450 3A Enzymes Are Key Contributors for Hepatic Metabolism of Bufotalin, a Natural Constitute in Chinese Medicine Chansu

Metabolism of IMM-H004 and Its Pharmacokinetic-Pharmacodynamic Analysis in Cerebral Ischemia/Reperfusion Injured Rats

Effect of P. corylifolia on the pharmacokinetic profile of tofacitinib and the underlying mechanism

Atypical Pharmacodynamic Properties and Metabolic Profile of the Abused Synthetic Cannabinoid AB-PINACA: Potential Contribution to Pronounced Adverse Effects Relative to Δ9-THC

Typical and atypical metabolic characteristics of three iridaceae isoflavone components: in vitro and in silico studies

Inhibitory mechanism of vortioxetine on CYP450 enzymes in human and rat liver microsomes