Human Metabolites | List of Frontiers open access articles

Original Research

Published on 13 May 2015

Understanding the foundations of the structural similarities between marketed drugs and endogenous human metabolites

in Drug Metabolism and Transport

Steve O'Hagan
Douglas B. Kell

Frontiers in Pharmacology

doi 10.3389/fphar.2015.00105

10,034 views
32 citations

Original Research

Published on 17 Dec 2021

Human Metabolites of Hamaforton™ (Hamamelis virginiana L. Extract) Modulates Fibroblast Extracellular Matrix Components in Response to UV-A Irradiation

in Ethnopharmacology

Fausta Natella
Barbara Guantario
Roberto Ambra
Giulia Ranaldi
Federica Intorre
Carolina Burki
Raffaella Canali

Frontiers in Pharmacology

doi 10.3389/fphar.2021.747638

4,875 views
5 citations

Original Research

Published on 08 Aug 2024

From serum metabolites to the gut: revealing metabolic clues to susceptibility to subtypes of Crohn’s disease and ulcerative colitis

in Systems Endocrinology

Fan Li
Zhaodi Wang
Tongyu Tang
Qi Zhao
Zhi Wang
Xiaoping Han
Zifeng Xu
Yu Chang
Hongyan Li
Sileng Hu

Frontiers in Endocrinology

doi 10.3389/fendo.2024.1375896

4,652 views
2 citations

Original Research

Published on 14 Mar 2017

Neuroprotective Effects of Selected Microbial-Derived Phenolic Metabolites and Aroma Compounds from Wine in Human SH-SY5Y Neuroblastoma Cells and Their Putative Mechanisms of Action

in Nutrition and Food Science Technology

A. Esteban-Fernández
C. Rendeiro
J. P. E. Spencer
D. Gigorro del Coso
M. D. González de Llano
B. Bartolomé
M. V. Moreno-Arribas

Frontiers in Nutrition

doi 10.3389/fnut.2017.00003

25,113 views
35 citations

Original Research

Published on 11 Apr 2024

ICH S1 prospective evaluation study: weight of evidence approach to predict outcome and value of 2-year rat carcinogenicity studies. A report from the regulatory authorities subgroup

in Regulatory Toxicology

Todd Bourcier
Timothy McGovern
Tania Cavaliero
Geoffrey Ebere
Akiyoshi Nishikawa
Jihei Nishimura
Kumiko Ogawa
Markku Pasanen
Alisa Vespa
Jan Willem Van der Laan

Frontiers in Toxicology

doi 10.3389/ftox.2024.1353783

7,984 views
9 citations

Original Research

Published on 22 Aug 2016

MetMaxStruct: A Tversky-Similarity-Based Strategy for Analysing the (Sub)Structural Similarities of Drugs and Endogenous Metabolites

in Drug Metabolism and Transport

Steve O'Hagan
Douglas B. Kell

Frontiers in Pharmacology

doi 10.3389/fphar.2016.00266

9,482 views
32 citations

Articles

Understanding the foundations of the structural similarities between marketed drugs and endogenous human metabolites

Human Metabolites of Hamaforton™ (Hamamelis virginiana L. Extract) Modulates Fibroblast Extracellular Matrix Components in Response to UV-A Irradiation

From serum metabolites to the gut: revealing metabolic clues to susceptibility to subtypes of Crohn’s disease and ulcerative colitis

Neuroprotective Effects of Selected Microbial-Derived Phenolic Metabolites and Aroma Compounds from Wine in Human SH-SY5Y Neuroblastoma Cells and Their Putative Mechanisms of Action

ICH S1 prospective evaluation study: weight of evidence approach to predict outcome and value of 2-year rat carcinogenicity studies. A report from the regulatory authorities subgroup

MetMaxStruct: A Tversky-Similarity-Based Strategy for Analysing the (Sub)Structural Similarities of Drugs and Endogenous Metabolites